The sequencing and DNA analysis of human pedigrees represents a gold standard technique for the identification and diagnostics of rare genetic diseases. In this effort, distinguishing between maternally and paternally inherited mutations is crucial. However, currently available tools are not designed for haplotype-resolved human genome assemblies, such as those currently produced by the Telomere-To-Telomere (T2T) consortium. To address this gap, the student will develop a tool that precisely estimates the meiotic recombination breakpoints (i.e. switches between parental haplotypes), using traditional pairwise alignments, as well as experimental pangenome graph structures. Further, the student will demonstrate the utility of the developed tool using both simulated and real datasets (family trio with haplotype-resolved assemblies for child, as well as mother and father). The developed tool should be easy to install and well-documented, to facilitate potential adoption by the scientific community.