aVLFA0822c Pharmacology II - practice

Faculty of Medicine
spring 2027
Extent and Intensity
0/3/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (alternate examiner)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
Carlos Daniel Ferreira Fonseca, MSc. (seminar tutor)
PharmDr. Katarína Kostolanská, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (assistant)
Mgr. Jana Kubátová, Ph.D. (assistant)
MUDr. Jana Nováková, Ph.D. (assistant)
doc. PharmDr. Jana Rudá, Ph.D. (assistant)
Mgr. Barbora Říhová, Ph.D. (assistant)
PharmDr. Petr John (seminar tutor)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Prerequisites
aVLFA0721p Pharmacology I - lecture && aVLPF0622p Pathophysiology II - lecture
Pharmacology II builds on the previous semester's Pharmacology I.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
The aim of the course is to introduce students to the basic pharmacological profiles of selected groups of drugs (mechanism of action, pharmacokinetic properties, methods of application,  indications, adverse effects, drug interactions, and contraindications) and to apply theoretical knowledge at the level of selecting the appropriate drug to ensure safe and effective pharmacotherapy.
Learning outcomes
After completing the course, students will have an overview of the drug groups used in clinical practice, be familiar with the basic pharmacological profiles of individual drugs, and be able to select and prescribe a medicinal product for a patient based on a known diagnosis, using the available information and a drug database. The choice of drug is based on consideration of all factors affecting its safety and efficacy.
Key topics
  • aVLFA0822c - Pharmacology II practicals

  • General medicine

  • Spring semester 

  • 1. ANTIPSYCHOTICS, ANTIPARKINSONICS, PROKINETICS
  • Content of the lesson: Classification of psychotropic medicines, pharmacology of dopaminergic system with the focus on antipsychotics, antiparkinsonics and prokinetics.
  • 2. ANTIDEPRESSANTS
  • Content of the lesson: Pharmacological review of antidepressants, cognitive enhancers and psychostimulants.
  • 3. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
  • Content of the lesson: GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, adverse effects. Rules in the therapy of anxiety, sleeping disorders and seizures with respect to specific subpopulations. Psychopharmacological case reports. Drug dependence and its treatment.
  • 4. GENERAL AND LOCAL ANAESTHETICS
  • Content of the lesson: Basic pharmacological features of general and local anaesthetics. Review of drugs used in premedication.
  • 5. VASODILATORS AND DRUGS WITH EFFECT ON VESSELS
  • MCQ TEST I 
  • Content of the lesson: Lipid-lowering drugs, nitrates, donors of NO groups, calcium channel blockers and other groups of direct vasodilators. Risk factors of cardiovascular diseases.
  • 6. DRUGS INFLUENCING RAAS. DIURETICS.
  • Content of the lesson: ACE inhibitors, sartans, inhibitors of renin, diuretics. Antagonists of mineralocorticoid receptors. Antihypertensives of the 1st and 2nd choice, combined therapy.
  • 7. DRUGS DIRECTLY INFLUENCING MYOCARDIUM
  • Content of the lesson: Beta-blockers and bradins, drugs with positive inotropic effects. Calcium channel blockers - non-DHP, antiarrhythmics. Therapy of heart failure.
  • 8. DRUGS INFLUENCING HAEMOSTASIS
  • Content of the lesson: Classification of drugs interfering with the process of haemostasis, pharmacological review of anticoagulants, antiplatelet drugs, fibrinolytics and antianaemics.
  • 9. THERAPY OF INTOXICATIONS
  • MCQ TEST II 
  • Principles of therapy of intoxications: toxidroms, specific and non-specific therapy of intoxications, antidotes. Work with websites of toxicological centres.
  • 10. ANTI-INFECTIVES I – ANTIBACTERIAL SUBSTANCES
  • Content of the lesson: Pharmacological review of antibiotics, PK/PD parameters, selection of ATB, case reports, bacterial resistance.
  • 11. ANTI-INFECTIVES II – ANTIFUNGAL AND ANTIVIRAL DRUGS, DERMATOLOGICS
  • Content of the lesson: Therapy of respiratory infections, UTI, intensive care. Overview of antimycotics and antivirotics, Dermatologics – classification and pharmacological review, local anti-infectives, revision of drug prescription.
  • 12. PHARMACOLOGY OF GIT
  • PRESCRIPTION TEST
  • Content of the lesson: Pharmacological review of drugs used in GIT disorders.
  • 13. CYTOSTATICS AND TARGETED THERAPY IN ONCOLOGY
  • Content of the lesson: Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
  • 14. DRUG INTERACTIONS
  • MCQ TEST III
  • Content of the lesson: Case reports focused on drug interactions.
  • 15. PHYTOPHARMACOLOGY
  • Content of the lesson: Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-treatment of selected diseas

Study resources and literature
    required literature
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
  • LANDA, Leoš; Jan JUŘICA; Kristýna NOSKOVÁ and Ondřej ZENDULKA. Selected chapters from general pharmacology for students of general medicine and dentistry at MF MU. Brno, 2020. info
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    recommended literature
  • Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • Library of case reports: https://is.muni.cz/auth/do/med/el/case_reports/index_en.html
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
Approaches, practices, and methods used in teaching
Participation in pharmacology exercises requires students to prepare for class by studying the study materials provided in advance in the MUNI IS. The exercises themselves further deepen theoretical knowledge by interconnecting individual topics, applying theoretical knowledge to specific examples from clinical practice, and reinforcing long-term knowledge through active learning. The instructor encourages active discussion, guides students through the resolution of individual cases with targeted questions, and responds to the needs of the seminar group being taught. At the same time, however, the instructor adheres to the pre-set schedule for each teaching unit so that uniform learning outcomes are maintained.
Method of verifying learning outcomes and course completion requirements

Participation in exercises is mandatory. Students are allowed two unexcused absences. To obtain credit, students must successfully pass the following tests:


Prescription test - students are tasked with prescribing 2 HVLP using a drug database. The assignment includes indications and other patient information necessary for the correct selection of the drug and duration of therapy (drug form/route of administration, quantity of the product).


3x Multiple-choice test - each test contains 15 questions, the number of correct answers is specified in the assignment for each question, the pass mark is 6 points, and a total of 20 points from 3 tests. It is possible to retake one test, but only once per semester.


To obtain credit, students must meet the attendance requirement and pass all tests with a minimum total of 20 points.

Alternate completion
During an internship, it is possible to access the seminars online. Tests are written in person after returning from the internship. This option should be discussed with the course contact person before the start of the semester.
Language of instruction
English
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2027/aVLFA0822c/
Consultation hours and test substitutions/corrections are always in the week following the test in the Dpt. of Pharmacology classroom after logging in via the IS Topic Lists.
Study support
https://is.muni.cz/auth/el/1411/jaro2027/aVLFA0822c/
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025, spring 2026.
  • Enrolment Statistics (spring 2027, recent)
  • Permalink: https://is.muni.cz/course/med/spring2027/aVLFA0822c