VLFA08222c Pharmacology II - practice

Faculty of Medicine
spring 2022
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
MUDr. Róbert Balog (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (seminar tutor)
MVDr. Eva Dražanová, Ph.D. (seminar tutor)
PharmDr. Tomáš Hammer (seminar tutor)
Mgr. Mária Hricková (seminar tutor)
PharmDr. Eva Klásková (seminar tutor)
PharmDr. Katarína Kostolanská (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
MUDr. Filip Šiška (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Květoslava Sedlářová (assistant)
doc. PharmDr. Jana Rudá, Ph.D. (alternate examiner)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Barbora Říhová, Ph.D.
Supplier department: Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
VLFA07212p Farmakologie I - přednáška
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to acquiant the students with drugs from selected pharmacotherapeutic groups and to learn them how to use the drugs rationally with respect to their mode of action, indications and contraindications.
Learning outcomes
At the end of the course student should be able choose and prescribe suitable drug for the patient with known indicication. The selection will be made with respect to all factors influencing drug safety and efficacy.
Syllabus
  • aVLFA08222c - Pharmacology II practicals

    General medicine

    Spring semester 2021

  • 1. DRUGS OF DISEASES WITH CHRONIC PULMONARY OBSTRUCTION, H 1 -ANTIHISTAMINES, COUGH MEDICINES.
  • Review of drugs used in the therapy of diseases with chronic pulmonary obstruction, inhalational pharmaceutical forms. Generations of H1 antihistamines and their indications. Cough medicines – classification, modes of action, use in specific subpopulations.
  • 2. ANTIPSYCHOTICS, ANTIPARKINSONICS, PROKINETICS
  • Classification of psychotropic medicines, Pharmacology of dopaminergic system with the focus on antipsychotics, antiparkinsonics and prokinetics.
  • 3. ANTIDEPRESSANTS
  • Pharmacological review of antidepressants, cognitive enhancers and psychostimulants.
  • 4. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
  • GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, AE including the risk of abuse. Rules in the therapy of sleeping disorders and seizures with respect to specific subpopulations. Psychopharmacological case reports.
  • 5. DRUGS INFLUENCING MYOCYTES, HYPOLIPIDEMIC DRUGS
  • TEST No. 1
  • Beta-blockers, nitrates, antiarrhythmic drugs, hypolipidemic drugs, antiobesity drugs. Risk factors of cardiovascular disorders. Pharmacotherapy of acute and chronic ischaemic heart disease.
  • 6. DRUGS INFLUENCING RAAS, DIURETICS
  • ACE inhibitors, AT-II receptor antagonists, renin antagonists, diuretics, mineralocorticoid receptor antagonists, positive inotropics. Pharmacotherapy of acute and chronic heart failure.
  • 7. VASODILATORS, ANTIHYPERTENSIVES
  • Ca channel blockers, central antihypertensives, alfa-1 blockers, PDE-5 inhibitors, prostacyclin inhibitors, endothelin inhibitors. Pharmacotherapy of hypertension. Antihypertensive drug combinations. Overview of cardiovascular drugs.
  • 8. DRUGS INFLUENCING HAEMOSTASIS
  • Classification of drugs interfering with the process of hemostasis, pharmacological review of anticoagulants, antiplatelets, fibrinolytics and antianemics.
  • 9. ANTI-INFECTIVES I - ANTIBIOTICS
  • TEST No. 2
  • Pharmacological review of antibiotics, bacterial resistance, respiratory infections, UTI and intensive care antibiotics.
  • 10. ANTI-INFECTIVES II – ANTIMYCOTICS AND ANTIVIRALS
  • Dermatologics – classification and pharmacological review, local anti-infectives, revision of drug prescription.
  • 11. DRUGS OF GIT
  • PRESCRIPTION TEST
  • Pharmacological review of drugs in diseases of GIT.
  • 12. CYTOSTATICS AND TARGETED THERAPY IN ONCOLOGY
  • Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
  • 13. THERAPY OF INTOXICATIONS AND ADDICTION
  • Principles of therapy of intoxications and substance addiction. Case reports.
  • 14. DRUG INTERACTIONS
  • TEST No. 3
  • Case reports on drug-drug interactions.
  • 15. PHYTOPHARMACOLOGY
  • Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-treatment of selected diseases. Credits.
Literature
    required literature
  • RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016. xv, 760. ISBN 9780702053627. info
    recommended literature
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020. xvi, 789. ISBN 9780702074486. info
  • Farmakologie. Edited by Jan Švihovec - Jan Bultas - Pavel Anzenbacher - Jaroslav Chládek - J. 1. vydání. Praha: Grada Publishing, 2018. xix, 962. ISBN 9788024755588. info
  • Základy speciální receptury léčivých přípravků, Juřica a kol., 2013, http://portal.med.muni.cz/clanek-611-zaklady-specialni-receptury-lecivych-pripravku.html
    not specified
  • Studijní materiály: http://portal.med.muni.cz/disciplina-13-farmakologie
  • Knihovna kazuistik: https://is.muni.cz/auth/do/med/el/case_reports/index.html
  • Atlas léčivých rostlin, https://is.muni.cz/auth/do/med/el/lecive_rostliny/atlas.html
  • Markova farmakoterapie vnitřních nemocí. Edited by Josef Marek - Michal Vrablík. 5., zcela přepracované a d. Praha: Grada, 2019. xxiv, 868. ISBN 9788024750781. info
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015. xi, 664. ISBN 9781451191776. info
Teaching methods
Drug classes from the Syllabus are actively reviewed by students and supported by the teacher. Possible ambiguities are discussed and learned knowledge is practiced in case reports from real clinical practice. The training of drug prescription with the use of drug compendia and the computer databases.
Assessment methods
The participation in practicals is obligatory and registered. Students can miss two classes without excuse. To get credits a students have to pass 4 written tests:

Prescription test
2 RMP, the indication or pharmacotherapeutic gorup is stated together with a basic data of the patient significant for correct drug selection
3 Multiple-choice tests
15 questions, number of correct answers indicated, minimal score to pass 6
one of the tests can be repeated once

The credits will be given to students who: passed the prescription test and scored at least 6 points from each of multiple-choice tests and their total score from these tests is higher than 20.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 45.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms spring 2019, spring 2020, spring 2021.
  • Enrolment Statistics (recent)
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