LF:aVLFA0822c Pharmacology II -pr.

aVLFA0822c Pharmacology II - practice

Faculty of Medicine
spring 2019

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. PharmDr. Ondřej Zendulka, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLFA0822c/30: Thu 28. 2. 16:00–18:30 A19/229, Thu 7. 3. 16:00–18:30 A19/229, Thu 14. 3. 16:00–18:30 A19/229, Thu 21. 3. 16:00–18:30 A19/229, Thu 28. 3. 16:00–18:30 A19/229, Thu 4. 4. 16:00–18:30 A19/229, Thu 11. 4. 16:00–18:30 A19/229, Thu 18. 4. 16:00–18:30 A19/229, Thu 25. 4. 16:00–18:30 A19/229, Thu 2. 5. 16:00–18:30 A19/229, Thu 9. 5. 16:00–18:30 A19/229, Thu 16. 5. 16:00–18:30 A19/229, Thu 23. 5. 16:00–18:30 A19/229, Thu 30. 5. 16:00–18:30 A19/229, Thu 6. 6. 16:00–18:30 A19/229, L. Součková
aVLFA0822c/31: Thu 28. 2. 16:00–18:30 A19/229, Thu 7. 3. 16:00–18:30 A19/229, Thu 14. 3. 16:00–18:30 A19/229, Thu 21. 3. 16:00–18:30 A19/229, Thu 28. 3. 16:00–18:30 A19/229, Thu 4. 4. 16:00–18:30 A19/229, Thu 11. 4. 16:00–18:30 A19/229, Thu 18. 4. 16:00–18:30 A19/229, Thu 25. 4. 16:00–18:30 A19/229, Thu 2. 5. 16:00–18:30 A19/229, Thu 9. 5. 16:00–18:30 A19/229, Thu 16. 5. 16:00–18:30 A19/229, Thu 23. 5. 16:00–18:30 A19/229, Thu 30. 5. 16:00–18:30 A19/229, Thu 6. 6. 16:00–18:30 A19/229, J. Pistovčáková
aVLFA0822c/32: Fri 1. 3. 13:00–15:30 A19/326, Fri 8. 3. 13:00–15:30 A19/326, Fri 15. 3. 13:00–15:30 A19/326, Fri 22. 3. 13:00–15:30 A19/326, Fri 29. 3. 13:00–15:30 A19/326, Fri 5. 4. 13:00–15:30 A19/326, Fri 12. 4. 13:00–15:30 A19/326, Fri 26. 4. 13:00–15:30 A19/326, Fri 3. 5. 13:00–15:30 A19/326, Fri 10. 5. 13:00–15:30 A19/326, Fri 17. 5. 13:00–15:30 A19/326, Fri 24. 5. 13:00–15:30 A19/326, Fri 31. 5. 13:00–15:30 A19/326, Fri 7. 6. 13:00–15:30 A19/326, O. Zendulka
aVLFA0822c/33: Mon 25. 2. 16:00–18:30 A19/229, Mon 4. 3. 16:00–18:30 A19/229, Mon 11. 3. 16:00–18:30 A19/229, Mon 18. 3. 16:00–18:30 A19/229, Mon 25. 3. 16:00–18:30 A19/229, Mon 1. 4. 16:00–18:30 A19/229, Mon 8. 4. 16:00–18:30 A19/229, Mon 15. 4. 16:00–18:30 A19/229, Mon 29. 4. 16:00–18:30 A19/229, Mon 6. 5. 16:00–18:30 A19/229, Mon 13. 5. 16:00–18:30 A19/229, Mon 20. 5. 16:00–18:30 A19/229, Mon 27. 5. 16:00–18:30 A19/229, Mon 3. 6. 16:00–18:30 A19/229, J. Pistovčáková
aVLFA0822c/34: Mon 25. 2. 13:00–15:30 A19/229, Mon 4. 3. 13:00–15:30 A19/229, Mon 11. 3. 13:00–15:30 A19/229, Mon 18. 3. 13:00–15:30 A19/229, Mon 25. 3. 13:00–15:30 A19/229, Mon 1. 4. 13:00–15:30 A19/229, Mon 8. 4. 13:00–15:30 A19/229, Mon 15. 4. 13:00–15:30 A19/229, Mon 29. 4. 13:00–15:30 A19/229, Mon 6. 5. 13:00–15:30 A19/229, Mon 13. 5. 13:00–15:30 A19/229, Mon 20. 5. 13:00–15:30 A19/229, Mon 27. 5. 13:00–15:30 A19/229, Mon 3. 6. 13:00–15:30 A19/229, J. Juřica

Prerequisites (in Czech)

aVLFA0721p Pharmacology I - lecture && aVLPF0622p Pathological Phys. II - lect.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

General Medicine (programme LF, M-VL)

Course objectives

The aim of the course is to acquiant the students with drugs from selected pharmacotherapeutic groups and to learn them how to use the drugs rationally with respect to their mode of action, indications and contraindications.

Learning outcomes

At the end of the course student should be able choose and prescribe suitable drug for the patient with known indicication. The selection will be made with respect to all factors influencing drug safety and efficacy.

Syllabus

aVLFA08222c - Pharmacology II practicals

General medicine

Spring semester 2019
week 25. 2. - 1. 3.
1. ANTIPSYCHOTICS, ANTIPARKINSONICS, PROKINETICS
Content of the lesson: Classification of psychotropic medicines, pharmacology of dopaminergic system with the focus on antipsychotics, antiparkinsonics and prokinetics.
Self-study/getting ready for the lesson: Revision of dopamine physiology. Content of the lecture. Prokinetics.
week 4. 3. - 8. 3.
2. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
Content of the lesson: GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, AE including the risk of abuse. Rules in the therapy of sleeping disorders and seizures with respect to specific subpopulations
Self-study/getting ready for the lesson: Revision of TDM, pharmacotherapy in pregnancy. Content of the lecture.
week 11. 3. - 15. 3.
3. ANTIDEPRESSANTS
Content of the lesson: Pharmacological review of antidepressants and psychostimulants. Neuropsychopharmacological case reports.
Self-study/getting ready for the lesson: Content of the lecture. Revision of topics 1 and 2. Psychostimulants, psychotomimetics.
week 18. 3. - 22. 3.
4. DRUGS OF DISEASES WITH CHRONIC PULMONARY OBSTRUCTION, H₁-ANTIHISTAMINES, COUGH MEDICINES.
Content of the lesson: Review of drugs used in the therapy of diseases with chronic pulmonary obstruction, inhalational pharmaceutical forms. Generations of H₁ antihistamines and their indications. Cough medicines – classification, modes of action, use in specific subpopulations.
Self-study/getting ready for the lesson: Revision of pathophysiology of allergy and diseases with chronic pulmonary obstruction. Content of the lecture. Cough medicines (antitussives and mucoactive drugs).
week 25. 3. - 29. 3.
TEST No. 1
5. ANTIANGIAL DRUGS
Content of the lesson: Fundamentsal of the therapy of angina pectoris and acute myocardial infarction. Direct vasodilating agents, calcium channel blockers, beta blockers, hypolipidemics.
Self-study/getting ready for the lesson: Review of pythophysiology of ischemic heart disease, atherosclerosis and myocardial infarction. Content of the lecture. Hypolipidemics, anti-obesity medications.
week 1. 4. – 5. 4.
6. ANTIHYPERTENSIVES
Content of the lesson: Pharmacological review of antihypertensives with focus on diuretics and drugs targeting RAAS. Combinations of antihypertensives.
Self-study/getting ready for the lesson: Revision of pathophysiology of hypertension. Beta blockers, calcium channel blockers. α₁ sympatholytics, α₂ sympathomimetics. Content of the lecture.
week 8. 4. – 12. 4.
7. DRUGS OF HEART FAILURE, ANTIARRHYTHMICS
Content of the lesson: Pharmacological review of cardiotonics and other drugs with positive inotropic effect. Medicines of acute and chronic heart failure. Classification and review of antiarrhytmics.
Self-study/getting ready for the lesson: Revision of pathophysiology of heart failure and arrythmias. Content of the lecture. Calcium channel blockers, beta blockers, ACEi, local anesthetics.
week 15. 4. – 19. 4.
8. DRUGS INFLUENCING HEMOSTASIS
Content of the lesson: Classification of drugs interfering with the process of hemostasis, pharmacological review of anticoagulants, antiplatelets, fibrinolytics and antianemics.
Self-study/getting ready for the lesson: Revision of hemostasis. Content of the lecture. Antianemics.
week 22. 4. – 26. 4.
TEST No. 2
9. ANTI-INFECTIVES I - ANTIBIOTICS
Content of the lesson: Pharmacological review of antibiotics, bacterial resistance, respiratory infections, UTI and intensive care antibiotics.
Self-study/getting ready for the lesson: Revision of ATB from microbiology (betalactams, macrolides, AMG, TTC, lincosamides, (lipo)glycopeptides, quinolones, sulfonamides, nitroimidazoles, nitrofurans). Content of the lecture.
week 29. 4. – 3. 5.
10. ANTI-INFECTIVES II – ANTIMYCOTICS AND ANTIVIRALS
Content of the lesson: Dermatologics – classification and pharmacological review, local anti-infectives, revision of drug prescription.
Self-study/getting ready for the lesson: Content of the lecture. Dermatologics, antiparasitics.
week 6. 5. – 10. 5.
11. DRUGS OF GIT
Content of the lesson: Pharmacological review of drugs in diseases of GIT.
Self-study/getting ready for the lesson: Revision of physiology of GIT, pathophysiology of vomiting and ulcers. Antispasmodics, prokinetics. Content of the lecture. Drugs influencing the production and release of bile.
week 13. 5. – 17. 5.
12. CYTOSTATICS AND TARGETED THERAPY IN ONCOLOGY
Content of the lesson: Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
Self-study/getting ready for the lesson: Revision of cancer cell biology and the cell cycle phases. Repetition of basic pharmacological principles of targeted therapy. Content of the lecture.
week 20. 5. – 24. 5.
TEST Rp.
13. THERAPY OF INTOXICATIONS
Content of the lesson: Principles of therapy of intoxications. Case reports on drug intoxications.
Self-study/getting ready for the lesson: Content of the lecture. Substance abuse.
week 27. 5. – 31. 5.
TEST No. 3
14. DRUG INTERACTIONS
Content of the lesson: Students’ presentations – case reports on drug-drug interactions from clinical courses with proposed solution.
Self-study/getting ready for the lesson: Pharmacokinetics, pharmacodynamics. Content of the lecture. Collecting of case reports during clinical courses and consultations with professors.
week 3. 6. – 7. 6.
15. PHYTOPHARMACOLOGY
Content of the lesson: Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-tretament of selected diseases.
Self-study/getting ready for the lesson: Content of the lecture. Drug-drug interactions.

Literature

required literature

RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info

recommended literature

Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info

not specified

Library of case reports: https://is.muni.cz/auth/do/med/el/case_reports/index_en.html

Teaching methods

Drug classes specifics from the Syllabus are firstly briefly reviewed by the teacher, the discussion on possible ambiguities are discussed and learned knowledge is practicesed in case reports from real clinical practice. The training of drug prescription with the use of drug compendia and the computer databases.

Assessment methods

The participation in practicals is obligatory and registered. Students can miss one class without excuse. To get credits a students have to pass 4 written tests:

Prescription test
a) 2 RMP, the indication or pharmacotherapeutic gorup is stated together with a basic data of the patient significant for correct drug selection
Multiple-choice tests
15 questions, number of correct answers indicated, minimal score to pass 6
one of the tests can be repeated once

The credits will be given to students who: passed the prescription test and scored at least 6 points from each of multiple-choice tests and their total score from these tests is higher than 20.

Language of instruction

English

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 45.

Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2018, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.

Enrolment Statistics (spring 2019, recent)
Permalink: https://is.muni.cz/course/med/spring2019/aVLFA0822c

LF:aVLFA0822c Pharmacology II -pr. - Course Information

aVLFA0822c Pharmacology II - practice

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