BVBC021s Biochemistry - seminar

Faculty of Medicine
spring 2026
Extent and Intensity
0/2/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Iva Audy (assistant)
doc. RNDr. Jiří Dostál, CSc. (assistant)
RNDr. Hana Paulová, CSc. (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Guaranteed by
Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Marie Tomandlová, Ph.D.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Prerequisites (in Czech)
BVLC011c Medical Chemistry -p && BVLC011s Med.Chem.-seminar
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The student will get acquainted with the basic metabolic pathways and their signifikance.
Learning outcomes
In the end of the course will students:
- understand the properties and function of enzymes
- describes basic catabolic and anabolic pathways of carbohydrate, lipid and protein metabolism
- understand the principles of energy production, utilization and deposition at the cellular level
- explain the function of cell membranes and the transport processes on the membrane
- describe protein synthesis, understand the relationship between protein structure and function
- explain the function of hemoglobin in oxygen transport and maintaining acid-base balance
Syllabus
  • Introduction to cell metabolism. The structure of biomembranes. Membrane transport.
  • Kinetics of enzyme reactions.
  • Enzyme cofactors.
  • Three phases of nutrient catabolism. Citrate cycle.
  • Respiratory chain. Oxidative phosphorylation. Reactive oxygen species.
  • Carbohydrate digestion. Glucose metabolism. Glycogen metabolism. Metabolism of fructose and galactose.
  • Digestion and intracellular degradation of proteins. Elimination of α-carboxyl and α-amino nitrogen from amino acids. Ammonia detoxification.
  • Significant reactions in amino acid transformations.
  • Lipid digestion. Synthesis and breakdown of fatty acids. Synthesis of triacylglycerols, phospholipids, cholesterol and bile acids. Lipoperoxidation. Eicosanoids.
  • Heme biosynthesis and degradation. Hemoglobin.
  • Metabolism of purine and pyrimidine nucleotides. Uric acid.
Literature
    required literature
  • Studijní materiály dostupné v Interaktivní osnově předmětu v IS MU.
  • LEDVINA, Miroslav; Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny. 3. vydání. Praha: Univerzita Karlova, nakladatelství Karolinum, 2020, 269 stran. ISBN 9788024647487. info
    recommended literature
  • FERRIER, Denise R. Lippincott's illustrated Q&A review of biochemistry. Seventh edition. Wolters Kluwer, 2017. ISBN 9781496344496. info
  • MATOUŠ, Bohuslav. Základy lékařské chemie a biochemie. 1. vyd. Praha: Galén, 2010, xv, 540. ISBN 9788072627028. info
  • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. Translated by Vladimír Benda - Martin Vejražka - Jiří Jonák. 1. české vydání. Praha: Grada, 2012, xiv, 498. ISBN 9788024729770. info
Teaching methods
Seminary course. Class discussions on assigned topics.
Assessment methods
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught every week.
General note: Úspěšné absolvování je předpokladem pro přistoupení ke zkoušce v předmětu BVBC021p.
Teacher's information
Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MU in the Course-related instructions.
  • Permalink: https://is.muni.cz/course/med/spring2026/BVBC021s