K1MA1_15 Introduction to Analytical Chemistry

Faculty of Pharmacy
Spring 2026
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
Mgr. Michaela Kuchynka, Ph.D. (lecturer)
doc. RNDr. Bc. Jiří Pazourek, Ph.D. (lecturer)
Guaranteed by
Mgr. Michaela Kuchynka, Ph.D.
Department of Chemical Drugs – Departments – Faculty of Pharmacy
Prerequisites (in Czech)
K1AC1_15 General and Inorganic Chemistr && K1PC1_15 Practical Classes in Chemistry
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
To provide theoretical knowledge from the chemical and instrumental analysis of inorganic and organic substances, emphasizing the importance of methods in the analysis of cosmetic products and in the study of structural and physicochemical properties of substances related to their biological effect. Emphasis is placed on the formation of logical thought processes important for future professional application. The course is an introduction to chemical analysis, which is a prerequisite for completing additional courses related to the applied analysis of cosmetic products.
Learning outcomes
After completing the course, the student will be able to understand the meaning and principles of classical and modern analytical chemistry - to have an overview of the methods of qualitative and quantitative analytical chemistry.
Syllabus
Topic 1: Introduction to Analytical Chemistry The essence and fundamental concepts of analytical chemistry, basic classification of analytical methods, and analytical reactions. The significance of analytical chemistry in the cosmetic industry. Accuracy, precision, detection limit, and quantification limit. Topic 2: Buffer Solutions Buffers pH Indicators Topic 3: Sample Collection and Preparation Methods for collecting samples of cosmetic products. Sample preparation for analysis (extraction, filtration, dilution). The effect of the sample matrix on analytical methods. Topic 4: Solutions and Weighing Definition of solutions. Methods of expressing solution composition. Volume measurement techniques. Types of balances and weighing techniques. Practical examples from cosmetic products. Topic 5: Volumetric Analysis I – Classical Chemical Methods Definition and principles of volumetric analysis. Preparation of standard solutions. Primary substances in volumetric analysis. Determination of the exact concentration of standard solutions. Acid-base titrations. Practical examples from cosmetic products. Topic 6: Volumetric Analysis II – Classical Chemical Methods Precipitation titrations. Complexometric titrations. Redox titrations. Topic 7: Classical Chemical Methods – Gravimetry Principles of gravimetric methods. Application of gravimetry in cosmetic product analysis (determination of inorganic components). Topic 8: Instrumental Methods I Overview of inorganic compound analysis and their identification. Quantitative vs. qualitative analysis, calibration curves, and preparation of standard solutions. Topic 9: Instrumental Methods II – Doc. Pazourek Qualitative analysis methods for organic compounds, structural analysis – NMR, Infrared Spectroscopy (IR). Topic 10: Instrumental Methods III Qualitative analysis methods for organic compounds, structural analysis – Mass Spectrometry (MS). UV-VIS Spectroscopy – Principles of absorption spectrophotometry, quantification of dyes and UV filters in cosmetic products. Atomic Absorption Spectroscopy (AAS) – Determination of heavy metals in cosmetic products. Topic 11: Instrumental Methods IV – Separation Techniques – Doc. Pazourek Selected separation methods: basic principles, chromatographic methods (HPLC, TLC). Liquid chromatography (HPLC) in the analysis of active ingredients in cosmetics. Topic 12: Instrumental Methods V – Separation Techniques – Doc. Pazourek Gas Chromatography (GC) – principles, analysis of perfumes and essential oils. Coupling chromatography with mass spectrometry (LC-MS, GC-MS). Topic 13: Advanced Instrumental Methods – Research Applications Inductively Coupled Plasma Spectrometry (ICP) – elemental analysis, nanoparticle detection. Imaging techniques – LA-ICP-MS, Computed Tomography (CT). Topic 14: Summary, Review, and Practical Analytical Case Studies Case studies of cosmetic product analysis. Discussion and preparation for the final exam
Literature
    recommended literature
  • SKOOG, Douglas A.; Donald M. WEST; F. James HOLLER and Stanley R. CROUCH. Analytická chemie. Translated by Karel Nesměrák - Václav Červený - Tomáš Křížek - Eliška. Vydání první. Praha: Vysoká škola chemicko-technologická v Praze, 2019, xxx, 950. ISBN 9788075920430. info
  • KLOUDA, Pavel. Moderní analytické metody. Třetí, upravené vydání. Ostrava: Pavel Klouda - nakladatelství Pavko, 2016, 176 stran. ISBN 9788086369228. info
    not specified
  • Analysis of cosmetic products. Edited by Amparo Salvador - Alberto Chisvert Sanía. Second edition. Amsterdam: Elsevier, 2018, xviii, 606. ISBN 9780444635082. info
  • Štulík, K. a kolektiv. Analytické separační metody. UK Praha, 2004. info
  • Kalous, V. Jak moderní chemie zkoumá strukturu molekul. Praha, 1983. info
Teaching methods
Oral lessons
Assessment methods
Oral exam
Language of instruction
Czech
Follow-Up Courses
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2025.
  • Enrolment Statistics (recent)
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