FaF:aF1FC1_14 Physiology and Pathophysiolo I - Course Information
aF1FC1_14 Human Physiology and Pathophysiology I
Faculty of PharmacySpring 2026
- Extent and Intensity
- 2/1/0. 3 credit(s). Type of Completion: z (credit).
In-person direct teaching - Teacher(s)
- MUDr. Tomáš Parák, Ph.D. (lecturer)
MUDr. Tomáš Parák, Ph.D. (seminar tutor)
MUDr. Marta Chalupová, Ph.D. (lecturer)
doc. MVDr. Pavel Suchý, Ph.D. (lecturer)
MVDr. Lada Tlučhořová (lecturer)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (lecturer)
MVDr. Jana Doležalová, Ph.D. (lecturer)
PharmDr. Lenka Paráková, Ph.D. (lecturer)
PharmDr. Lenka Paráková, Ph.D. (seminar tutor)
prof. MUDr. Jiří Vítovec, CSc. (lecturer)
PhDr. Gabriela Kuzmínová, MBA (lecturer)
Mgr. Noemi Arači (lecturer)
Mgr. Noemi Arači (seminar tutor) - Guaranteed by
- MUDr. Tomáš Parák, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy - Timetable
- Thu 15:30–17:10 45-135
- Timetable of Seminar Groups:
aF1FC1_14/02: each odd Thursday 8:00–9:40 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/03: each even Thursday 10:00–11:40 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/04: each odd Thursday 10:00–11:40 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/05: each even Thursday 11:50–13:30 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/06: each odd Thursday 11:50–13:30 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/07: each even Thursday 13:40–15:20 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová
aF1FC1_14/08: each odd Thursday 13:40–15:20 44-140, N. Arači, J. Doležalová, M. Chalupová, A. Kružicová, G. Kuzmínová, T. Parák, L. Paráková, P. Suchý, L. Tlučhořová, J. Vítovec - Prerequisites (in Czech)
- STUDIJNI_SKUPINA(nastup_2025)
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Pharmacy (programme FaF, M-FARM)
- Abstract
- Human physiology is defined as a science of the functions of healthy organism at the level of cell, tissue, organ and organ systems. Pathophysiology is focused on etiopathogenesis - the mechanisms which lead from the primary cause via individual malfunctions to subsequent development of clinical symptoms of disease. Knowledge of these mechanisms serves to develop a suitable and efficient therapy and prevent resultant damage.
- Learning outcomes
- After completing the course, the student will be able to:
- describe the physiology and pathophysiology of the main organs
- recognize subjective and objective symptoms of diseases
- examine the main physiological functions
- interpret examination results - Key topics
- PHYSIOLOGY AND PATHOPHYSIOLOGY I - LECTURES:
1. Introduction into pathophysiology, symptoms of diseases and their diagnosing. Disease development. Genetic factors in pathogenesis.
2. General physiological principles. Cell physiology. Function of cell membrane and intracellular structures. Basic principles of physiological regulation.
3. Nonspecific defence mechanisms. Inflammation. Stress. Damage of organism (physical, chemical and biological)
4. Specific defensive mechanisms and their disorders. Cell-mediated and antibody immunity. White blood cells, functions and disorders.
5. Physiology of the locomotive apparatus. Most common diseases of bones, muscles and joints. Inflammatory and degenerative rheumatic diseases.
6. Physiology of digestion and absorption, metabolism of sacharides, fats and proteins. Nutritional disorders, obesity and starving. Metabolic syndrome.
7. Vitamins, mineral substances and trace elements. Hyper and hypovitaminoses. Diseases of deficiency and excess of mineral substances and trace elements.
8. Physiology of blood formation. Differential diagnosing of anaemia.
9. Hemostasis and hemocoagulation. Coagulation cascade and its disorders. Hemorrhagic and hypercoagulable states.
10. Physiology of the circulatory system. Formation and development of atherosclerosis. Ischemic heart disease.
11. Formation and transmission of excitement and its disorders. Inherited and acquired heart disorders.
12. Basic principles of the blood pressure regulation. Hypertensive disease. Hypotension. Circulation failure (shock).
13. Theory of the formation of malignant growth. Tumours and their classification. Overview of clinically most common cancers.
Syllabus of exercises:
I. Basic physiological functions and their watching
1. Anamnesis, interview
2. Objective and subjective anamnesis
3. Basic checkup (examinations)
II. Cardiovascular system
1. Auscultation of heart sounds
2. Measurement of blood pressure
3. Electrocardiography
III. Respiratory system
1. Auscultation of lungs
2. Spirometry, Pulse oxymetry
3. Basal metabolism
IV. Nervous system
1. Hearing tests
2. Eye tests
3. Optical illusions
4. EEG
V. Urogenital tract, diabetes mellitus
1. Semi-quantitative urinalysis
2. Specific weight of urine
3. Kidney functions
4. Menstrual cycle, ovulation, gravidity
VI. Blood, Good laboratory practice
1. Red blood cells
2. Blood count
3. Haematocrit
4. Erythrocyte sedimentation
5. Differential leukocytes count
VII. Obtaining credits - Study resources and literature
- Approaches, practices, and methods used in teaching
- Lectures, seminars, exercises, exercises in selected examination techniques, consultations
- Method of verifying learning outcomes and course completion requirements
- To gain credits: Data analysis, eventualyy seminar papers on given topics, written test or an oral exam.
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- Study Materials
- Teacher's information
- Participation at seminars and excercises 100% and knowledge of recomended literature in the extent of lectures, seminars and excercises of this course are reqired. Without recognition the course or granting the credits is not possible to continue the following course Human Physiology and Pathophysiology II.
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/pharm/spring2026/aF1FC1_14