C6212 Biotechnology

Faculty of Science
Spring 2025
Extent and Intensity
2/0/0. 2 credit(s) (plus 2 credits for an exam). Type of Completion: zk (examination).
Teacher(s)
Mgr. Jiří Kučera, Ph.D. (lecturer)
doc. RNDr. Vladimír Velebný, CSc. (lecturer)
Ing. Matouš Čihák (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Kateřina Dadáková, Ph.D. (lecturer)
Ing. Jan Červený, Ph.D. (lecturer)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: Mgr. Jiří Kučera, Ph.D.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The objectives are the principles of traditional and modern biotechnology and the fundamental processes in fermentors and other devices that enable the biotechnological use of the metabolic activity of organisms and enzymes. An overview of representative biotechnologies using microbial, plant, and animal cell cultures.
Learning outcomes
After completing the course, a student will be able to:
- identify and describe traditional and modern biotechnologies;
- describe the factors influencing the biotechnological processes;
- apply principles of biotechnology to a practical problem;
- analyze current scientific knowledge in the field of biotechnology;
- design a suitable biotechnological plan applying good manufacturing practice.
Syllabus
  • Kučera: Microbial and enzyme biotechnology, a historical overview. Biochemical and chemical principles of traditional and modern biotechnology. Biological materials in biotechnology. Environmental biotechnology. Use of biological systems for remediation of contaminated environments and for environment-friendly processes.
  • Velebný, Čihák: Pharmaceutical biotechnology in the production of important drugs. The basic scheme of biotechnological drug production, typical stages, and their peculiarities.
  • Rotrekl: Animal biotechnology. Introduction to animal cells, potency and differentiation, immortalized lines, culture, and their differentiation. The use of animal and stem cells in screening and drug production. Animal cells and cell therapy. Special applications and future outlook (3D culturing, organoids, 3D printing of cells, in vitro creation of tissue and organ substitutes).
  • Dadáková, Červený: Plant biotechnology. Biology and physiology of plant cells. Methods of preparing GMO crops, their uses and risks. Plant production of biotechnologically interesting substances. Biochemistry and biology of algae. The use of algae and cyanobacteria in biotechnology. Biofuels, dietary supplements. Photobioreactors.
Literature
    recommended literature
  • Applied plant cell biology : cellular tools and approaches for plant biotechnology. Edited by Peter Nick - Zdeněk Opatrný. Berlin: Springer, 2014, xiv, 481. ISBN 9783642417863. info
  • Agricultural biotechnology. Edited by Hemant Rawat. Jaipur, India: Oxford Book Co., 2008, 277 p. ISBN 9788189473235. info
  • Advances in biotechnology. Edited by S. N. Jogdand. Rev. ed. Mumbai [India]: Himalaya Pub. House, 2007, 311 p. ISBN 9788183182676. info
  • Basic biotechnology. Edited by Colin Ratledge - Bjørn Kristiansen. 3rd ed. Cambridge: Cambridge University Press, 2006, xiv, 666. ISBN 9780521549585. URL info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, xii, 302. ISBN 012049860X. info
Teaching methods
Lectures on selected chapters of biotechnology. Discussion of complex issues.
Assessment methods
Written exam (test questions).
Language of instruction
English
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
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