PřF:C5320 Theoretical Concepts of NMR - Course Information
C5320 Theoretical Concepts of Nuclear Magnetic ResonanceFaculty of Science
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
- prof. Mgr. Lukáš Žídek, Ph.D. (lecturer)
doc. RNDr. Radovan Fiala, CSc. (lecturer)
Mgr. Petr Louša (seminar tutor)
- Guaranteed by
- prof. Mgr. Lukáš Žídek, Ph.D.
National Centre for Biomolecular Research - Faculty of Science
Supplier department: National Centre for Biomolecular Research - Faculty of Science
- Mon 17. 9. to Fri 14. 12. Tue 9:00–10:50 C04/211
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 9 fields of study the course is directly associated with, display
- Course objectives
- The course objective is to provide theoretical description of nuclear magnetic spectroscopy and to make the student familiar with the following areas of the NMR Theory: Theoretical concepts of classical description using the vector model as well as of quantum mechanics needed for proper understanding of multi-dimensional NMR techniques are discussed. The product operator formalism is introduced to facilitate description of basic one and two-dimensional experiments frequently used in chemical research.
- Learning outcomes
- At the end of the course, the students will be able to
1. understand theoretical description of NMR spectroscopy
2. understand principles of modern methods of NMR spectroscopy used in organic and inorganic chemistry, biochemistry, strucutural biology and biophysics.
3. select the method suitable for given application.
4. analyze basic NMR experiments at the level of the vector model and of the product operator formalism.
5. identify parameters determining results of the experiments.
- 1. Magnetic moment in classical electromagnetism
- 2. Nuclear magnetic resonance
- 3. Relaxation
- 4. Signal acquisition and processing
- 5. Spin in quantum mechanics
- 6. Mixed state of non-interacting spins
- 7. Chemical shift, NMR experiment
- 8. Product operators, dipolar coupling
- 9. 2D spectroscopy, NOESY
- 10. J-coupling, spin echoes
- 11. INEPT, HSQC, APT
- 12. COSY
- recommended literature
- KEELER, James. Understanding NMR spectroscopy. Chichester: Wiley, 2005. xv, 459. ISBN 0470017872. info
- LEVITT, Malcolm H. Spin dynamics : basics of nuclear magnetic resonance. 2nd ed. Hoboken, NJ: John Wiley & Sons, 2008. xxv, 714. ISBN 9780470511176. info
- Protein NMR spectroscopyprinciples and practice. Edited by John Cavanagh. 2nd ed. Boston: Academic Press, 2007. xxv, 885 p. ISBN 012164491X. info
- HOCH, Jeffrey C. and Alan S. STERN. NMR data processing. New York: Wiley-Liss, 1996. xi, 196. ISBN 0471039004. info
- not specified
- BROWN, Keith C. Essential mathematics for NMR and MRI spectroscopists. Cambridge, UK: Royal Society of Chemistry, 2017. xvi, 867. ISBN 9781782627975. info
- Teaching methods
- Lectures, class discussion
- Assessment methods
- Oral examination
- Language of instruction
- Follow-Up Courses
- Further Comments
- Study Materials
The course can also be completed outside the examination period.
The course is taught annually.