aVLHE0221c Histologie a embryologie I - cvičení

Lékařská fakulta
jaro 2025
Rozsah
0/3/0. 45. 2 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
doc. MVDr. Martin Anger, CSc. (cvičící)
MUDr. Ivana Baltasová (cvičící)
prof. MUDr. RNDr. Svatopluk Čech, DrSc. (cvičící)
MUDr. Jana Dumková, Ph.D. (cvičící)
doc. MVDr. Aleš Hampl, CSc. (cvičící)
Mgr. Hana Kotasová, Ph.D. (cvičící)
doc. RNDr. Irena Koutná, Ph.D. (cvičící)
MVDr. Lenka Lišková (cvičící)
MVDr. Anna Mac Gillavry Danylevska, Ph.D. (cvičící)
MUDr. Eva Mecová (cvičící)
doc. MUDr. Miroslava Sedláčková, CSc. (cvičící)
MUDr. Veronika Sedláková, Ph.D. (cvičící)
Mgr. Eva Švandová, Ph.D. (cvičící)
doc. RNDr. Petr Vaňhara, Ph.D. (cvičící)
Ing. Nicole Ludikovská (pomocník)
Garance
doc. MVDr. Aleš Hampl, CSc.
Ústav histologie a embryologie – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: doc. MUDr. Miroslava Sedláčková, CSc.
Dodavatelské pracoviště: Ústav histologie a embryologie – Teoretická pracoviště – Lékařská fakulta
Předpoklady
aVLAN0121s Anatomie I - seminář && aVLBI0121c Biologie I - cvičení
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Course objectives
At the end of the course students should be able to:
1. Describe tissue processing for light and electron microscopy.
2. Understand and explain the structure of a cell, basic structural principles and function of connective tissues, features of epithelial tissue, the structure of different types of muscle tissue, structure and function of nervous tissue.
3. Identify tissue types in histologic slides.
4. Characterize the microscopic structure of some organs of the human body and explain correlations of tissues within organs.
5. Describe gamete development, explain the principle of meiosis and regulation of gametogenesis.
6. Define the early embryonic development as well as the development of fetal membranes, placenta and umbilical cord.
7. Characterize stages of embryonic development.
Výstupy z učení
At the end of the course students should be able to:
1. Describe tissue processing for light and electron microscopy.
2. Understand and explain the structure of a cell, basic structural principles and function of connective tissues, features of epithelial tissue, the structure of different types of muscle tissue, structure and function of nervous tissue.
3. Identify tissue types in histologic slides.
4. Characterize the microscopic structure of some organs of the human body and explain the correlations of tissues within organs.
5. Describe gamete development, explain the principle of meiosis and the regulation of gametogenesis.
6. Define the early embryonic development as well as the development of fetal membranes, placenta and umbilical cord.
7. Characterize stages of embryonic development.
Osnova
  • 1. Introduction, organization of practicals, teaching aids. Overview of histological methods. Tissue processing for light and electron microscopy - explanation and film. Basic histochemistry and immunocytochemistry.
  • 2. Cytology: Ultrastructure of the cell nucleus during interphase. Ultrastructure of cell organelles I (mitochondria, the Golgi apparatus, the endoplasmic reticulum, ribosomes, lysosomes).
  • 3. Ultrastructure of cell organelles II (peroxisomes, and the centriol). Cell inclusions. The arrangement of cell surfaces: apical, lateral, and basal ones. Intercellular junctions: adhering, occluding, and communicating ones.
  • 4. General embryology I. Aids: Set of embryological schemes and pictures (I).
  • 5. General embryology II. Aids: Set of embryological schemes and pictures (II).
  • 6. General histology: Use of the light microscope, common faults in microscopy. Results of basic staining methods in histology: Hematoxylin-eosine /HE/ (hepar), hematoxylin–eosine-saffron /HES/ (esophagus), AZAN (prostate), impregnation (cerebellum). Connective tissue proper - classification and examples. Slides: Funiculus umbilicalis, Esophagus, Posterior segment of the eye, Lien, Aorta.
  • 7. Supporting tissues: cartilage and bone. Histogenesis of the bone tissue (ossification). Slides: Trachea, Auricula, Elastic cartilage, Lamellar bone, Chondrogenic ossification.
  • 8. Epithelial tissue: epithelial membranes (covering epithelia) and glandular epithelium. Slides: Ren, Vesica fellea, Trachea, Esophagus, Ureter, Palpebra, Skin from the finger tip.
  • 9. Glandular epithelium. Skides: Intestinum tenue, Glandula parotis, Glandula submandibularis.
  • 10. Nerve tissue. Slides: Cortex cerebri, Cerebellum, Medulla spinalis, Ganglion spinale, Peripheral nerve, Motor end plate.
  • 11. Muscle tissue. Slides: Apex linguae, Cardiac muscle tissue Intestinum tenue.
  • 12. Blood cells: Preparation of blood smears and their staining. Cytology of formed elements of blood. Differential white cell count (dWCC) - average values, abnormities and terminology of dWCC. Slide: A smear of peripheral blood stained by Pappenheim's method. Credits
Literatura
    doporučená literatura
  • VAŇHARA, Petr, Miroslava SEDLÁČKOVÁ, Irena LAUSCHOVÁ, Svatopluk ČECH a Aleš HAMPL. Guide to General Histology and Microscopic Anatomy. 1. vyd. Brno: Masarykova univerzita, 2017. ISBN 978-80-210-8453-7. info
  • MESCHER, Anthony L. Junqueira's basic histology : text and atlas. 13th ed. New York: McGraw-Hill Medical, 2013, xi, 544. ISBN 9781259072321. info
    neurčeno
  • EROSCHENKO, Victor P. Di Fiore's atlas of histology with functional correlations. 9th ed. Philadelphia: Lippincott Williams-Wilkins, 2000, xv, 363. ISBN 0683307495. info
Výukové metody
Content of this course includes study of slides and electron micrographs in microscopic hall as well as class discussion on the base of materials in the text book. Electronic textbooks are presented also in: http://www.med.muni.cz/histol/atlas.htm
Metody hodnocení
Testing of knowledge: Students must prove a sufficient level of knowledge by written test examination. Each student completes 4 partial tests during the semester. Tests are evaluated by point for a correct answer. More than half the number of correct answers (points) is evaluated as "Passed". All of these tests must be successful. In case of failure, only 1 resit is possible. There is condition 4 from 4 (ie. 4 P / 4 regular tests) or 4 from 5 (ie. 3 P / 4 regular tests + 1 P / 1 resit). If a student does not fulfill this condition, the credit test follows in the relevant exam period. This test covers all topics studied during the semester. In case of failure in credit test, the credit will not be given and student must enroll the course again.
Conditions for obtaining credit: 1. Attendance at all practical exercises (100% participation, all absences must be regularly excused (in IS) and substituted).
2. Successful completion of all tests.
3. Submission of all protocols (correctly completed forms of protocols signed by the teacher).
Vyučovací jazyk
Angličtina
Informace učitele
Information about HE teaching is available on the Department poster in front of the Microscopic Hall and on the web site http://www.med.muni.cz/histology/education.
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