ZLFA0722c Pharmacology II - practice

Faculty of Medicine
autumn 2020
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
Mgr. Jana Merhautová, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
Filip Šiška (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Květoslava Sedlářová (assistant)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: Renata Bláblová
Supplier department: Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
ZLFA0621c Pharmacology I - pract. && ZLPA0622c Pathology II - practice && ZLPF0622c Pathophys. II - practice && ZLOR0641c Orthodontics I -pract. && ZLPD0631c Periodontology I - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course student should know how representatives of individual drug classes in the form of individually prepared pharmaceutical preparation and bulk drugs can be prescribed with the special attention paid to preparations used in dentistry. The student should be familiar with pharmacological profiles of therapeutic and adverse effects of particular drugs with an attention paid to common drug-drug interactions.
Learning outcomes
At the end of the course student should know how representatives of individual drug classes in the form of individually prepared pharmaceutical preparation and bulk drugs can be prescribed with the special attention paid to preparations used in dentistry. The student should be familiar with pharmacological profiles of therapeutic and adverse effects of particular drugs with an attention paid to common drug-drug interactions.
Syllabus
  • Day 1
  • 1/ OPIOID ANALGESICS.
  • Analgesics of morphine type. Pharmacotherapy of pain.
  • Prescription of narcotic and psychotropic agents - revision. Special prescription and practical use of analgesic preparations.
  • 2/ NON-OPIOID ANALGESICS, NON-STEROIDAL ANTIINFLAMMATORY DRUGS.
  • Classification, modes of action, topically applied antiinflammatory drugs. Special prescription of antiinflammatory drugs and antipyretics.
  • Getting ready for the next lesson: Revision of patophysiology of cancer diseases.
  • Day 2
  • 3/ ANTICANCER DRUGS
  • Overview, classification and mechanisms of action of anticancer drugs.
  • 4/ LOCAL AND GENERAL ANAESTHETICS.
  • Overview, classification and mechanisms of action, side effects.
  • Special prescription of local anaesthetics.
  • Getting ready for the next lesson: Basic psychic functions, receptors of CNS. Physiology of blood pressure regulation. Revision of PNS pharmacology-α1 sympatholytics, α2 sympathomimetics, β sympatholytics. Revision of physiology of Renin – Angiotensin – Aldosterone System.
  • Day 3
  • 5/ PSYCHOTROPIC DRUGS.
  • Classification and terminology of psychotropics. Review of their mechanisms of action.Pharmacology of anxiolytics and hypnosedatives. Mechanism of action of benzodiazepines. Drugs used for premedication and to sedate a patient before surgery.
  • Special prescription of hypnosedatives and psychostimulants, samples of herbal drugs.
  • Video-programme: Benzodiazepines.
  • 6/ ANTIHYPERTENSIVE AGENTS.
  • Introduction, classification, diuretics, beta blockers, ACE inhibitors, Ca 2+ blockers, and other hypertensives.
  • Getting ready for the next lesson: Classification of antimicrobial agents, mechanisms of resistance, mechanisms of effects of antibacterial agents.
  • Day 4
  • 7/ DRUGS USED IN DISORDERS OF BLOOD CLOTTING-ANTICOAGULANTS AND THROMBOLYTICSPSYCHOTROPIC DRUGS.
  • Classification of drugs affecting haemostasis, mechanisms of action, side effects, overview of drugs.
  • Prescription of individually prepared and ready made preparations – practice.
  • 8/ ANTIBACTERIAL AGENTS.
  • Basic classification, mechanisms of action.
  • ANTIBACTERIAL, ANTIVIRAL AND ANTIFUNGAL AGENTS – focusing on the treatment of diseases of the oral cavity.
  • Special prescription of individually prepared and ready made preparations – antibiotics.
  • Getting ready for the next lesson: Revision of praescription of selected groups of drugs (lessons 1 – 8 + + semester I). Revision of taught topics (lessons 1 – 8).
  • Day 5
  • 9/ FINAL PRESCRIPTION TEST
  • REVIEW OF DRUGS WITH LOCAL ACTION USED IN DENTISTRY (repetition from the spring semester) + SELECTED CASE REPORTS ON DRUGS FROM PREVIOUS LESSONS
  • Working on PC: Solving case reports.
  • Prescription of individually prepared and ready made preparations used in dentistry.
  • 10/ FINAL (CREDIT) TEST OF SPECIAL PHARMACOLOGY (groups of drugs from lessons 1 – 8)
  • SELECTED CASE REPORTS ON DRUGS FROM PREVIOUS LESSONS
  • Working on PC: Solving case reports.
  • Video-programme: EPS, General anaesthetics.
  • CREDITS.
Literature
    required literature
  • NOVÁKOVÁ, Jana, Barbora ONDRÁČKOVÁ and Alexandra ŠULCOVÁ. Základy receptury léčivých přípravků pro praktická cvičení z farmakologie - obor Zubní lékařství. Brno: Multimediální podpora výuky klinických a zdravotnických oborů: Portál Lékařské fakulty Masarykovy univerzity, 2010. 96 pp. ISSN 1801-6103. URL info
  • RANG, H. P. Rang & Dale's pharmacology. 8th ed. [Edinburgh]: Churchill Livingstone, 2016. xv, 760. ISBN 9780702053627. info
  • http://portal.med.muni.cz/clanek-461-farmakovigilance-a-propagace-leciv.html
  • http://portal.med.muni.cz/clanek-367-vyzkum-novych-leciv-od-zrodu-k-registraci.html
    recommended literature
  • ŠVIHOVEC, Jan a kol. Farmakologie, Praha: Grada, 2018. ISBN 978-80-247-5558-8. www.grada.cz/farmakologie-(1)-8687
  • LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007. xxiv, 672. ISBN 9788072623730. info
  • Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • ZELENKOVÁ, Olga and Alexandra ŠULCOVÁ. Speciální stomatologická receptura pro praktická cvičení z farmakologie (Special stomatological prescriptions for practicals in pharmacology). 2. přepracované vydání. Brno: Masarykova univerzita v Brně, 2000. 30 pp. ISBN 80-210-2433-X. info
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015. xi, 664. ISBN 9781451191776. info
    not specified
  • HADAŠOVÁ, Eva, Jana NOVÁKOVÁ, Jana PISTOVČÁKOVÁ, Jana VINKLEROVÁ, Alexandra ŠULCOVÁ and Olga STAROBOVÁ. Praktická cvičení z farmakologie (Practical lessons on pharmacology). 2. opravené a doplněné vyd. Brno: Vydavatelství MU Brno-Kraví Hora, 2003. 110 pp. Skripta. ISBN 80-210-2694-4. info
  • http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
  • https://is.muni.cz/auth/el/1411/podzim2008/ZLFA0722p/um/Zasady_antibioticke_ lecby.pdf?fakulta=1411;obdobi=4343;kod=ZLFA0722p
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
  • http://portal.med.muni.cz/disciplina-13-farmakologie
  • Pharmaceutical Practice. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone. , 3rd Ed. 2004. ISBN 0443 07206 X
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 2., zcela přeprac. a doplň. Praha: Grada, 2014. ISBN 9788024713564. info
  • DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006. 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
  • ŠULCOVÁ, Alexandra. Poznámky k přednáškám z farmakologie. 1. vyd. Brno: Masarykova univerzita, 1993. 97 s. ISBN 80-210-0640-4. info
Teaching methods
Drug classes specifics from the Syllabus are read firstly by the teacher and presented in video-programmes if available followed by discussion and training of drug prescription with the use of drug compendia. Approaches to "pharmacotherapeutical decisions" are practiced using the special PC programmes. Reports of students on a specific pharmacological topic followed by discussion are also included.
Assessment methods
Zápočtový test. The participation in practicals is obligatory and registered. To get credits a student has to pass 2 written tests: a) test on special drug presription (assessed individually by the teacher), b) multiple-choice test on knowledge of topics taught, which usually consists of 15 questions. Each question offers one or more correct options. Criterion for successful passing the test is defined as more than half correctly answered questions.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019.
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