ZLPF0622p Pathological Physiology II - lecture

Faculty of Medicine
spring 2024
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Taught in person.
prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MUDr. Michal Jurajda, Ph.D. (lecturer)
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
prof. RNDr. Michal Masařík, Ph.D. (lecturer)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (lecturer)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (assistant)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Supplier department: Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
ZLPF0521c Pathophysiol.I - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the subject is to train students in dynamic thinking about etiology and pathogenesis of diseases focused on special pathophysiology themes:
Pathophysiology of digestive system, nutrition deficits.
Pathophysiology of endocrine system, metabolic diseases.
Pathophysiology of hemopoietic system, neoplasias.
Rheumatic diseases. Immunologically conditioned diseases.
Pathophysiology of nervous system.
Pathophysiology of muscles and sensory organs.
Learning outcomes
Student will explain the difference between acute and chronic effects of hormones
Student discusses the pathophysiology of clinically significant endocrine disruption of the function
Student will describe the pathophysiology of clinically significant gastrointestinal disorders, from a clinical point of view
Student will describe the anemic syndrome including the effects of anemic hypoxia
Student discusses different classification of anemias
Student discusses the pathophysiological aspects of transfusion of blood and blood derivatives,
Student will describe the main categories of diseases of white blood cells
Student will sum up the etiopathogenesis of common diseases of the joints
Student demonstrates a knowledge of the etiopathogenesis of diseases of the muscle and neuromuscular plate
Student rattles off examples of failures of a sensory sensation
Student demonstrates examples of common neurodegenerative diseases of CNS
Student discusses the pathophysiology of epilepsy,
Student will use knowledge of the composition of cerebrospinal fluid
Student argues the importance of stability of intracranial pressure and its components for the creation of intracranial hypertension
Student will sum up the function of autonomous (vegetative) system
Student will sum up the function of movement system and consequences of its failure
Student describes the systems important for the existence of consciousness and waking
  • Pathophysiology of gastrointestinal system
  • Pathophysiological aspects of chosen allergic and autoimmune diseases
  • Pathophysiology of haematopoiesis
  • Pathophysiological aspects of oncologic emergencies
  • General pathophysiology of endocrine system.
  • Special pathophysiology of endocrine system
  • Pathophysiology of nutrition disorders
  • Pathophysiology of lipid metabolism defects
  • Pathophysiology of bone and muscles
  • Pathophysiology of vitamins
  • Pathophysiology of coagulation and anticoagulation therapy
  • Pathophysiology of nervous system: motoric system
  • Pathophysiology of nervous system: degenerative disorders
  • DNA diagnostics in complex diseases. Basic principles of pharmacogenomics and personalized medicine.
    required literature
  • NEČAS, Emanuel. Obecná patologická fyziologie. 3. vyd. Praha: Karolinum, 2009. 377 s. ISBN 9788024616889. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 2. vyd. Praha: Karolinum, 2009. s. 381-760. ISBN 9788024617121. info
Teaching methods
Assessment methods
Pathophysiology course is finalised by an oral exam. Student will select questions from 3 different topics and he/she is given time to prepare answers (up to 120 min). Following topics will be represented by 1 question in oral exam:
Set G: general pathophysiology
Set S1: circulatory, respiratory, excretory and nervous system pathophysiology
Set S2: gastrointestinal, endocrine, hematopoietic and musculoskeletal system pathophysiology
Study materials include practical tutorials, recommended literature and handouts provided for lectures.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023.
  • Enrolment Statistics (spring 2024, recent)
  • Permalink: https://is.muni.cz/course/med/spring2024/ZLPF0622p