ZLPF0622c Pathological Physiology II - practice

Faculty of Medicine
spring 2021
Extent and Intensity
0/2/0. 1 credit(s). Type of Completion: z (credit).
MUDr. Kamil Ďuriš, Ph.D. (seminar tutor)
MUDr. Michal Jurajda, Ph.D. (seminar tutor)
MUDr. Jan Máchal, Ph.D. (seminar tutor)
doc. RNDr. Michal Masařík, Ph.D. (seminar tutor)
Mgr. Lukáš Pácal, Ph.D. (seminar tutor)
doc. RNDr. Monika Pávková Goldbergová, Ph.D. (seminar tutor)
prof. MUDr. Anna Vašků, CSc. (seminar tutor)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (assistant)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Supplier department: Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
ZLPF0521c Pathophysiol.I - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The objective of the practical exercises and seminars from pathological physiology is to provide students basic idea about experimental work during pathological conditions (diseases).
Learning outcomes
Student will explain the explain the pathophysiology of selected GIT disorders;
Student demonstrates the principle of load test (oGTT) in an animal model of experimentally induced diabetes (alloxan);
Student shall identify clinically relevant parameters describe nutritional status (calorimetry, BMI, WHR index, the weight, the skin-fold thickness, bioimpedance, DEXA) ;
Student demonstrates onset of obstruction icterus induced by ligation of ductus choledochus. Student understands etiopathogenesis of other types of icterus (hemolytic, hepatic) and diagnostics of them using heme metabolites in urine, blood and stool using mitochondrial/cytoplasmatic membranes liver enzymes;
Student describes etiopathogenesis of venous thrombosis using data from experimental animal model;
Student discusses cerebrovascular disease, intracranial hypertension with regard to etiology;
Student discusses the connection with the development and progression of shock states with regard to the pathophysiology of anaphylactic shock.
  • Practical excercises:
  • Anaphylactic reaction. Shock states (tutorial)
  • Anaemias, microscopy. (tutorial)
  • Pathophysiology of selected disorders of GIT (tutorial) I
  • Pathophysiology of selected disorders of GIT (tutorial) II
  • Statistical analyses
  • Exp. induced diabetes mellitus – diagnosis by glucose tolerance test
  • Neuropathophysiology (tutorial)
  • Exp. induced haemolytic, hepatotoxic and obstruction jaundice in lab. animal. Use of enzyme (and other) markers in diagnostics of selected pathophysiological states.
  • Exp. induced vein thrombosis in lab. animal
  • Eating disorders (tutorial) + credits
Teaching methods
Practical training.
Assessment methods
Credit. Practical exercises are compulsory (absence can be excused only in case of sick leave). During the term, tutors can continuously test knowledge in written tests or students can be asked to elaborate special papers.Term tuition (blocks) is completed by credit, conditions for awarding credit are: i) participation in the practical exercises, ii) elaboration of protocols from experimental practical exercises, iii) further individually chosen tutor's criteria.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020.
  • Enrolment Statistics (spring 2021, recent)
  • Permalink: https://is.muni.cz/course/med/spring2021/ZLPF0622c