aFAFK1_14 Pharmacology I

Farmaceutická fakulta
jaro 2026

Předmět se v období jaro 2026 nevypisuje.

Rozsah
2/0/0. 28p. 3 kr. Ukončení: z.
Vyučující
doc. PharmDr. Jan Juřica, Ph.D. (přednášející)
PharmDr. Tereza Kauerová, Ph.D. (přednášející)
doc. PharmDr. Peter Kollár, Ph.D. (přednášející)
Garance
doc. PharmDr. Peter Kollár, Ph.D.
Ústav farmakologie a toxikologie – Ústavy – Farmaceutická fakulta
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Výstupy z učení
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Osnova
  • - Introduction into the pharmacology
  • - Preclinical and clinical drug testing
  • - Pharmacokinetic processes
  • - Pharmacokinetic parameters and their clinical significance
  • - Receptor theory. Types of receptors
  • - Mechanisms of transmembrane transport of drugs, transport of drugs across organ barriers
  • - Routes of drug administration
  • - Basic pharmacodynamic processes (Dose-drug relationship. - Intercellular signaling. Drug-receptor interaction)
  • - General principles of poisoning therapy. Drug addictions (classification, mechanisms of origin, possibilities of therapy)
  • - Factors influencing the effect of a drug
Literatura
    povinná literatura
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON a James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    doporučená literatura
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Výukové metody
lectures
Metody hodnocení
Written final test
Vyučovací jazyk
Angličtina
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