aFAFK3_14 Pharmacology III

Farmaceutická fakulta
jaro 2026

Předmět se v období jaro 2026 nevypisuje.

Rozsah
3/2/0. 42p+28s. 6 kr. Ukončení: zk.
Vyučující
doc. PharmDr. Jan Juřica, Ph.D. (přednášející)
PharmDr. Tereza Kauerová, Ph.D. (přednášející)
doc. PharmDr. Peter Kollár, Ph.D. (přednášející)
MVDr. Renata Blechová, Ph.D. (cvičící)
MUDr. Marta Chalupová, Ph.D. (cvičící)
PharmDr. Tereza Kauerová, Ph.D. (cvičící)
PharmDr. Bc. Hana Kotolová, Ph.D. (cvičící)
PharmDr. Zuzana Široká, Ph.D. (cvičící)
Garance
doc. PharmDr. Peter Kollár, Ph.D.
Ústav farmakologie a toxikologie – Ústavy – Farmaceutická fakulta
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Výstupy z učení
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Osnova
  • - General principles of antimicrobial treatment, mechanisms of resistance to ATB treatment, beta-lactam ATB
  • - Antimicrobial drugs (pharmacological groups of antibacterial drugs)
  • - Antivirals, antifungals
  • - Anti-infective drugs. Antiparasitic, antiprotozoic, antituberculotic, antileprotic drugs
  • - Pharmacology of the heart (antiarrhythmics, positive inotropes and treatment of acute and chronic heart failure)
  • - Pharmacology of essential hypertension
  • - Vascular pharmacology (vasoconstrictors, vasodilators, venotonics)
  • - Blood pharmacology (anemia, influencing blood clotting - anticoagulants, fibrinolytics, hemostatics, antifibrinolytics, antiaggregants, antithrombotics)
  • - Pharmacology of the respiratory system (Antiasthmatics, pharmacotherapy of chronic obstructive pulmonary disease. Cough-antitussive therapy, expectorants)
  • - H1 antihistamines. Antiemetics, prokinetics. Antivertiginosis, drugs used in the therapy of Ménière's disease and tinnitus
  • - Peripheral hormones and mediators (autacoids) and their pharmacological significance (histamine and antihistamines, serotonin, prostaglandins, NO, bradykinin
  • - Medicines affecting the thyroid gland. Pharmacotherapy of osteoporosis and other bone diseases
  • - Medicines used in DM type 1 therapy - Insulin and its analogs. The endocrine pancreas and glycemic control. Insulin therapy, application forms, regimens, acute care, complications
  • - Medicines used in DM type 2 therapy
  • - Hypolipidemics, antiobesitics (Lipid spectrum disorder, Atherosclerotic cardiovascular disease, cardiorenal syndrome)
  • - Pharmacology of female and male sex hormones (agonists, antagonists, contraceptives, hormone replacement therapy)
  • - Mineralocorticoids, glucocorticoids
  • - Immunopharmaceuticals (Immunosuppressants, immunomodulation)
  • - Cytostatics (drugs used in cancer therapy)
  • - Biological treatment and principles of targeted therapy
Literatura
    povinná literatura
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN a H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
    doporučená literatura
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Výukové metody
lectures, seminars
Metody hodnocení
Continusous and final written test, oral examination
Vyučovací jazyk
Angličtina
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