FAFT2_14 Pharmacology II

Farmaceutická fakulta
podzim 2020
Rozsah
3/3/0. 7 kr. Ukončení: zk.
Vyučující
PharmDr. Bc. Kateřina Horská, Ph.D. (přednášející)
doc. PharmDr. Peter Kollár, Ph.D. (přednášející)
doc. RNDr. Eva Račanská, CSc. (přednášející)
doc. PharmDr. Peter Kollár, Ph.D. (cvičící)
doc. RNDr. Eva Račanská, CSc. (cvičící)
PharmDr. Tereza Kauerová, Ph.D. (přednášející)
PharmDr. Tereza Kauerová, Ph.D. (cvičící)
Garance
doc. PharmDr. Peter Kollár, Ph.D.
Ústav farmakologie a toxikologie – Ústavy – Farmaceutická fakulta
Rozvrh
St 12:00–14:15 44-247
  • Rozvrh seminárních/paralelních skupin:
FAFT2_14/01: St 14:15–16:30 44-247, T. Kauerová, P. Kollár, E. Račanská
Předpoklady
FAKULTA(FaF) || OBOR(MUSFaF)
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Anotace
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Course contents:
The course is divided into general pharmacological principles and special pharmacology, i.e. into drug groups classified according to their influence on the functional systems of the organism (pharmacodynamic agents) or according to their anti-infective (antimicrobial, antiparasitic, antiviral, .. .) effects.
Výstupy z učení
After completing the course the student is able to define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Klíčová témata
Pharmacology of inflammation and immune response
Histamine. Histamine H1 receptor antagonists
Non-steroidal anti-inflammatory drugs.
Antirheumatoid drugs. Drugs for treatment of gout
Immunomodulators: Immunosuppressant drugs. Overview of immunostimulants
Pharmacology of the endocrine system
Thyroid hormones. Treatment of hypo- and hyperthyroidism
Diabetes mellitus. Treatment with insulin
Diabetes mellitus. Treatment with oral hypoglycaemic agents
Obesity and possibilities of treatment
Hormones of adrenal cortex: Glucocorticoids
Bone metabolism: Pharmacotherapy of osteoporosis
Pharmacology of the respiratory system
Pharmacotherapy of bronchial asthma
Chronic obstructive pulmonary disease. Drugs used for cough
Pharmacology of the central nervous system
Overview of neurotransmitters
General anaesthetics
Anxiolytic and hypnotic drugs
Antipsychotic drugs
Antidepressant drugs
Antiepileptic drugs. Overview of centrally acting muscle relaxants
Neurodegenerative disorders: Drugs in Parkinson´s disease, Alzheimer´s dementia
Opioid analgesics
CNS stimulants. Psychotomimetic agents (hallucinogens)
Ethanol - pharmacology, toxicology
Pharmacology of the gastrointestinal tract
Treatment of peptic ulcer disease
Drugs affecting vomiting
Therapy of constipation and acute diarrhoea: laxatives and antidiarrhoeal agents
Chemotherapy of infections
Antibacterial drugs
Sulfonamides. Trimethoprim
b-lactam antibiotics - penicillins
b-lactam antibiotics - cephalosporins and other b-lactam antibiotics. Bacitracin. Vancomycin. Polymixins
Tetracyclines. Chloramphenicol
Aminoglycosides
Macrolides. Lincosamides. Fusidic acid
Fluoroquinolones. Metronidazole. Nitrofurantoin
Antimycobacterial agents
Antituberculosis drugs. Overview of antileprosy drugs
Antiviral agents
Antifungal drugs
Antiparasitic drugs
Therapy of protozoal infections: trichomoniasis, toxoplasmosis, amoebosis. Overview of other protozoal infections
Antimalarial drugs
Anthelminthic drugs in helminth infections
Cancer chemotherapy
Overview of anticancer drugs
Studijní zdroje a literatura
    povinná literatura
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Humphrey P. Rang, Maureen M. Dale, James M. Ritter and Rod J. Fl. Rang & Dale's Pharmacology, 8th Edition. 2016. ISBN 978-0702053627. info
    doporučená literatura
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Přístupy, postupy a metody používané ve výuce
lectures, seminars
Způsob ověření výstupů z učení a požadavky na ukončení
The criterion for passing the course is to fulfill the attendance requirement at seminars and then to pass the exam test. The condition for passing the exam test is to achieve at least 55% of the maximum possible number of points.
Vyučovací jazyk
Angličtina
Odkaz a informace vyučujících
Conditions for successful completion of the course and obtaining credits are as follows:
1. Complete all seminars (100% Attendance is necessary) (according to Article 9, Paragraph 6 of the MU Study and Examination Regulations). In the case of excused absence – compensation for the absence from seminars would be in the form of a seminar paper (range 2–3 pages of A4 format) on a topic identical to the topic of the seminar, which a student could not attend. In the case of a long-term serious absence, it will be dealt with individually.
2. To score at least 55% to pass the exam test.
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