Stereotactic Body Radiation Therapy for Colorectal Cancer Liver
Metastases; Early Results

J 2012

Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results

BURKOŇ, Petr; Pavel ŠLAMPA; Tomáš KAZDA; Marek SLÁVIK; T. PROCHÁZKA et al.

Základní údaje

Originální název

Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results

Název česky

Stereotaktická radioterapie jaterních metastáz kolorektálního karcinomu; časné výsledky

Autoři

BURKOŇ, Petr; Pavel ŠLAMPA ; Tomáš KAZDA; Marek SLÁVIK; T. PROCHÁZKA a M. VRZAL

Vydání

Klinická onkologie, Praha, Česká lékařská společnost J.E.Purkyně, 2012, 0862-495X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/12:00063928

Organizační jednotka

Lékařská fakulta

Klíčová slova česky

kolorektální karcinom – metastázy – játra – radioterapie – extrakraniální stereotaktická terapie

Klíčová slova anglicky

colorectal neoplasms – neoplasm metastasis – liver – radiation therapy – stereotactic body radiotherapy

Příznaky

Recenzováno

Změněno: 20. 2. 2013 10:21, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

for treatment of colorectal cancer liver metastases. Materials and Methods: From September 2009 to December 2011, 11 patients with 15 inoperable liver metastases of colorectal cancer were treated by SBRT using Varian Clinac iX linear accelerator. We treated 6 men and 5 women of age from 51 to 81 years (median 68). SBRT doses ranged from 40 to 56 Gy (median 54 Gy) and were administered in 3 to 8 fractions. Results: Local control rates at 2, 4, 6, 9 and 12 months after completion of SBRT were 100%, 91%, 91%, 67% and 50%, respectively. Disease progression-free survival rates at 2, 4, 6, 9 and 12 months were 82%, 82%, 64%, 50% and 50%, respectively. Median follow-up was 15 months. No severe side effects were attributed to the therapy. Conclusion: Our study assessed the feasibility of SBRT in selected group of patients with 1 to 3 colorectal cancer liver metastases with no other treatment option. We achieved excellent local control and very moderate acute and late side effects. Distant metastases were the most common recurrence form after SBRT. SBRT demonstrated excellent local control and resulted in occasional long-term survivors without any serious side effects of therapy.

Citovat

BURKOŇ, Petr; Pavel ŠLAMPA; Tomáš KAZDA; Marek SLÁVIK; T. PROCHÁZKA a M. VRZAL. Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results. Klinická onkologie. Praha: Česká lékařská společnost J.E.Purkyně, 2012, roč. 25, SUPPL. 2, s. 2S93-2S97, 5 s. ISSN 0862-495X.

@article{1088089,
   author = {Burkoň, Petr and Šlampa, Pavel and Kazda, Tomáš and Slávik, Marek and Procházka, T. and Vrzal, M.},
   article_location = {Praha},
   article_number = {SUPPL. 2},
   keywords = {colorectal neoplasms – neoplasm metastasis – liver – radiation therapy – stereotactic body radiotherapy},
   language = {eng},
   issn = {0862-495X},
   journal = {Klinická onkologie},
   title = {Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results},
   url = {http://www.linkos.cz/files/klinicka-onkologie/174.pdf},
   volume = {25},
   year = {2012}
}

TY  - JOUR
ID  - 1088089
AU  - Burkoň, Petr - Šlampa, Pavel - Kazda, Tomáš - Slávik, Marek - Procházka, T. - Vrzal, M.
PY  - 2012
TI  - Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results
JF  - Klinická onkologie
VL  - 25
IS  - SUPPL. 2
SP  - 2S93-2S97
EP  - 2S93-2S97
PB  - Česká lékařská společnost J.E.Purkyně
SN  - 0862495X
KW  - colorectal neoplasms – neoplasm metastasis – liver – radiation therapy – stereotactic body radiotherapy
UR  - http://www.linkos.cz/files/klinicka-onkologie/174.pdf
N2  - for treatment of colorectal cancer liver metastases. Materials and Methods: From September 2009 to December 2011, 11 patients with 15 inoperable liver metastases of colorectal cancer were treated by SBRT using Varian Clinac iX linear accelerator. We treated 6 men and 5 women of age from 51 to 81 years (median 68). SBRT doses ranged from 40 to 56 Gy (median 54 Gy) and were administered in 3 to 8 fractions. Results: Local control rates at 2, 4, 6, 9 and 12 months after completion of SBRT were 100%, 91%, 91%, 67% and 50%, respectively. Disease progression-free survival rates at 2, 4, 6, 9 and 12 months were 82%, 82%, 64%, 50% and 50%, respectively. Median follow-up was 15 months. No severe side effects were attributed to the therapy. Conclusion: Our study assessed the feasibility of SBRT in selected group of patients with 1 to 3 colorectal cancer liver metastases with no other treatment option. We achieved excellent local control and very moderate acute and late side effects. Distant metastases were the most common recurrence form after SBRT. SBRT demonstrated excellent local control and resulted in occasional long-term survivors without any serious side effects of therapy.
ER  -

BURKOŇ, Petr; Pavel ŠLAMPA; Tomáš KAZDA; Marek SLÁVIK; T. PROCHÁZKA a M. VRZAL. Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results. \textit{Klinická onkologie}. Praha: Česká lékařská společnost J.E.Purkyně, 2012, roč.~25, SUPPL. 2, s.~2S93-2S97, 5 s. ISSN~0862-495X.

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