Alternation of retinoic acid induced neural differentiation of
P19 embryonal carcinoma cells by reduction of reactive oxygen
species intracellular production

J 2008

Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production

KONOPKA, Roman, Lukáš KUBALA, Antonín LOJEK a Jiří PACHERNÍK

Základní údaje

Originální název

Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production

Autoři

KONOPKA, Roman (203 Česká republika, domácí), Lukáš KUBALA (203 Česká republika, garant, domácí), Antonín LOJEK (203 Česká republika, domácí) a Jiří PACHERNÍK (203 Česká republika, domácí)

Vydání

NEUROENDOCRINOLOGY LETTERS, 2008 Oct;29(5):770-4, 2008, 0172-780X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Švédsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.359

Kód RIV

RIV/00216224:14310/08:00049587

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000261553200033

Klíčová slova anglicky

embryonal carcinoma cells; neural differentiation; redox status; antioxidants

Štítky

Pb, rivok

Změněno: 20. 4. 2012 09:25, Ing. Andrea Mikešková

Anotace

V originále

Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus regulate cell physiology including proliferation and differentiation. However, the role of ROS in neuronal differentiation of embryonic pluripotent cells is unknown. For this reason, the modification of retinoic acid (RA) induced neuronal differentiation of mouse embryonal carcinoma cells P19 by selected ROS scavengers and flavoprotein inhibitor was evaluated.

Návaznosti

GP524/03/P171, projekt VaV

Název: Mechanismy řídící neurální diferenciaci myších embryonálních kmenových buněk in vitro

Investor: Grantová agentura ČR, Mechanismy řídící neurální diferenciaci myších embryonálních kmenových buněk in vitro

Citovat

KONOPKA, Roman, Lukáš KUBALA, Antonín LOJEK a Jiří PACHERNÍK. Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production. NEUROENDOCRINOLOGY LETTERS. 2008 Oct;29(5):770-4, 2008, roč. 29, č. 5, s. 770-774. ISSN 0172-780X.

@article{819204,
   author = {Konopka, Roman and Kubala, Lukáš and Lojek, Antonín and Pacherník, Jiří},
   article_number = {5},
   keywords = {embryonal carcinoma cells; neural differentiation; redox status; antioxidants},
   language = {eng},
   issn = {0172-780X},
   journal = {NEUROENDOCRINOLOGY LETTERS},
   title = {Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/18987612?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum},
   volume = {29},
   year = {2008}
}

TY  - JOUR
ID  - 819204
AU  - Konopka, Roman - Kubala, Lukáš - Lojek, Antonín - Pacherník, Jiří
PY  - 2008
TI  - Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production
JF  - NEUROENDOCRINOLOGY LETTERS
VL  - 29
IS  - 5
SP  - 770-774
EP  - 770-774
PB  - 2008 Oct;29(5):770-4
SN  - 0172780X
KW  - embryonal carcinoma cells
KW  - neural differentiation
KW  - redox status
KW  - antioxidants
UR  - http://www.ncbi.nlm.nih.gov/pubmed/18987612?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
L2  - http://www.ncbi.nlm.nih.gov/pubmed/18987612?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
N2  - Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus regulate cell physiology including proliferation and differentiation. However, the role of ROS in neuronal differentiation of embryonic pluripotent cells is unknown. For this reason, the modification of retinoic acid (RA) induced neuronal differentiation of mouse embryonal carcinoma cells P19 by selected ROS scavengers and flavoprotein inhibitor was evaluated.
ER  -

KONOPKA, Roman, Lukáš KUBALA, Antonín LOJEK a Jiří PACHERNÍK. Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production. \textit{NEUROENDOCRINOLOGY LETTERS}. 2008 Oct;29(5):770-4, 2008, roč.~29, č.~5, s.~770-774. ISSN~0172-780X.

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