| VESELSKÁ, Renata, Jan ŠKODA, Tomáš LOJA, Karel ZITTERBART, Zdeněk PAVELKA, Jana ŠMARDOVÁ, Iveta VALÁŠKOVÁ, Markéta HERMANOVÁ a Jaroslav ŠTĚRBA. An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line. Child's Nervous System. Berlin / Heidelberg: Springer, 2010, roč. 26, č. 6, s. 841-846. ISSN 0256-7040. |
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@article{883371,
author = {Veselská, Renata and Škoda, Jan and Loja, Tomáš and Zitterbart, Karel and Pavelka, Zdeněk and Šmardová, Jana and Valášková, Iveta and Hermanová, Markéta and Štěrba, Jaroslav},
article_location = {Berlin / Heidelberg},
article_number = {6},
keywords = {glioblastoma multiforme; EGFR ; p53; FISH; FASAY; karyotyping},
language = {eng},
issn = {0256-7040},
journal = {Child's Nervous System},
title = {An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line},
volume = {26},
year = {2010}
}
TY - JOUR
ID - 883371
AU - Veselská, Renata - Škoda, Jan - Loja, Tomáš - Zitterbart, Karel - Pavelka, Zdeněk - Šmardová, Jana - Valášková, Iveta - Hermanová, Markéta - Štěrba, Jaroslav
PY - 2010
TI - An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line
JF - Child's Nervous System
VL - 26
IS - 6
SP - 841-846
EP - 841-846
PB - Springer
SN - 02567040
KW - glioblastoma multiforme
KW - EGFR
KW - p53
KW - FISH
KW - FASAY
KW - karyotyping
N2 - This study report on a case of glioblastoma multiforme with a polyploid karyotype including a very unusual genetic change - the loss of a copy of the EGFR gene at locus 7p11.2 (EGFR gene) - diagnosed in a 14.5-year-old boy. To date, this patient has survived event-free for 34 months. A detailed analysis of the HGG-02 cell line, which was derived from this primary tumor, was also performed.
ER -
VESELSKÁ, Renata, Jan ŠKODA, Tomáš LOJA, Karel ZITTERBART, Zdeněk PAVELKA, Jana ŠMARDOVÁ, Iveta VALÁŠKOVÁ, Markéta HERMANOVÁ a Jaroslav ŠTĚRBA. An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line. \textit{Child's Nervous System}. Berlin / Heidelberg: Springer, 2010, roč.~26, č.~6, s.~841-846. ISSN~0256-7040.
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