BAFF Levels Are Elevated in Paediatric Patients With Acute
Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms

J 2012

BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms

BIENERTOVÁ VAŠKŮ, Julie; Petr BIENERT; Daniela KODYTKOVÁ; Filip ZLÁMAL; Josef TOMANDL et. al.

Základní údaje

Originální název

BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms

Autoři

BIENERTOVÁ VAŠKŮ, Julie; Petr BIENERT; Daniela KODYTKOVÁ; Filip ZLÁMAL ; Josef TOMANDL ; Marie TOMANDLOVÁ; Anna VAŠKŮ a Jaroslav ŠTĚRBA

Vydání

Journal of Hematology, Elmer Press, 2012, 1927-1212

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/12:00060622

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.4021/jh104e

Klíčová slova anglicky

B-cell activating factor; Acute lymphoblastic leukaemia; B-cell lymphoma; Paediatric

Změněno: 20. 8. 2012 11:05, Mgr. Michal Petr

Anotace

V originále

There is emerging evidence that B-lineage neoplasms have aberrant expression of B-cell activating factor (BAFF) that enables the B cells to escape apoptosis. The aim of the study therefore was to investigate circulating levels of BAFF in paediatric malignancies related to B-cell growth, i.e. B-cell acute lymphoblastic leukaemia (B-ALL) and B-lineage lymphomas. We observed significant differences in circulating levels of BAFF between the B-ALL patients and B-cell lymphoma patients (Bcp-ALL: 7764 plus-minus 6329 pg/ml, Bcell lymphoma: 2675 plus-minus 1544 pg/ml; P = 0.0268), the circulating levels of BAFF being substantially higher in B-ALL cases.

Přiložené soubory

JH_BAFF.pdf

Požádat o autorskou verzi souboru

Citovat

BIENERTOVÁ VAŠKŮ, Julie; Petr BIENERT; Daniela KODYTKOVÁ; Filip ZLÁMAL; Josef TOMANDL; Marie TOMANDLOVÁ; Anna VAŠKŮ a Jaroslav ŠTĚRBA. BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms. Journal of Hematology. Elmer Press, 2012, roč. 1, č. 1, s. 20-22. ISSN 1927-1212. Dostupné z: https://doi.org/10.4021/jh104e.

@article{989621,
   author = {Bienertová Vašků, Julie and Bienert, Petr and Kodytková, Daniela and Zlámal, Filip and Tomandl, Josef and Tomandlová, Marie and Vašků, Anna and Štěrba, Jaroslav},
   article_number = {1},
   doi = {https://doi.org/10.4021/jh104e},
   keywords = {B-cell activating factor; Acute lymphoblastic leukaemia; B-cell lymphoma; Paediatric},
   language = {eng},
   issn = {1927-1212},
   journal = {Journal of Hematology},
   title = {BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms},
   volume = {1},
   year = {2012}
}

TY  - JOUR
ID  - 989621
AU  - Bienertová Vašků, Julie - Bienert, Petr - Kodytková, Daniela - Zlámal, Filip - Tomandl, Josef - Tomandlová, Marie - Vašků, Anna - Štěrba, Jaroslav
PY  - 2012
TI  - BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms
JF  - Journal of Hematology
VL  - 1
IS  - 1
SP  - 20-22
EP  - 20-22
PB  - Elmer Press
SN  - 19271212
KW  - B-cell activating factor
KW  - Acute lymphoblastic leukaemia
KW  - B-cell lymphoma
KW  - Paediatric
N2  - There is emerging evidence that B-lineage neoplasms have aberrant expression of B-cell activating factor (BAFF) that enables the B cells to escape apoptosis. The aim of the study therefore was to investigate circulating levels of BAFF in paediatric malignancies related to B-cell growth, i.e. B-cell acute lymphoblastic leukaemia (B-ALL) and B-lineage lymphomas. We observed significant differences in circulating levels of BAFF between the B-ALL patients and B-cell lymphoma patients (Bcp-ALL: 7764 plus-minus 6329 pg/ml, Bcell lymphoma: 2675 plus-minus 1544 pg/ml; P = 0.0268), the circulating levels of BAFF being substantially higher in B-ALL cases.
ER  -

BIENERTOVÁ VAŠKŮ, Julie; Petr BIENERT; Daniela KODYTKOVÁ; Filip ZLÁMAL; Josef TOMANDL; Marie TOMANDLOVÁ; Anna VAŠKŮ a Jaroslav ŠTĚRBA. BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms. \textit{Journal of Hematology}. Elmer Press, 2012, roč.~1, č.~1, s.~20-22. ISSN~1927-1212. Dostupné z: https://doi.org/10.4021/jh104e.

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