CORE126 Modern technologies for life-science research

Pan-university studies
Spring 2026
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. Jiří Nováček, Ph.D. (lecturer)
doc. Mgr. Karel Kubíček, Ph.D. (lecturer)
MVDr. Boris Tichý, Ph.D. (lecturer)
Mgr. Vojtěch Bystrý, Ph.D. (lecturer)
prof. RNDr. Zbyněk Zdráhal, Dr. (lecturer)
Mgr. Josef Houser, Ph.D. (lecturer)
doc. RNDr. Radovan Fiala, CSc. (lecturer)
doc. RNDr. Radka Svobodová, Ph.D. (lecturer)
Mgr. Jan Přibyl, Ph.D. (lecturer)
Mgr. Milan Ešner, Ph.D. (lecturer)
Ing. Michal Mikl, Ph.D. (lecturer)
Mgr. Miloslava Kollarčíková (assistant)
Guaranteed by
Mgr. Jiří Nováček, Ph.D.
Central European Institute of Technology
Contact Person: Mgr. Miloslava Kollarčíková
Supplier department: Cryo-Electron Microscopy and Tomography Core Facility – Centre for Structural Biology – Central European Institute of Technology
Timetable
Wed 10:00–11:50 B11/305
Prerequisites (in Czech)
MAXATR(3, core)
Course Enrolment Limitations
The course is offered to students of any study field.
The capacity limit for the course is 120 student(s).
Current registration and enrolment status: enrolled: 8/120, only registered: 0/120, only registered with preference (fields directly associated with the programme): 0/120
Abstract
The course will provide an introduction to understanding the structure of the basic building blocks of the cell and will cover the description of biophysical methods that can be used to study them.
Learning outcomes
Upon completion of the course, the student will be able to:
- explain the principles of modern technologies used in biological and biomedical research;
- understand basic principles of methods for studying the structure and function of biomolecules, including sequencing, proteomics, NMR spectroscopy, crystallography, and microscopy;
- understand basic principles of interpretation of experimental data obtained from different life science techniques;
- compare the advantages and limitations of different methods and select the appropriate approach for solving specific research problems;
- design experimental strategies for studying biological systems.
Key topics
  • 18.2.: Principles of MRI and Its Applications in Neuroimaging (Ing. Michal Mikl, Ph.D.)
  • 25.2.: Basic Building Blocks of the Cell (doc. Mgr. Karel Kubíček, Ph.D.)
  • 4.3..: Principles of Methods for Studying Nucleic Acid Sequences (MVDr. Boris Tichý, Ph.D.)
  • 11.3.: Analysis of Sequencing Data (Mgr. Vojtěch Bystrý, Ph.D.)
  • 18.3.: Biophysical Methods for Studying Structures and Interactions of Proteins and Nucleic Acids (Mgr. Josef Houser, Ph.D.)
  • 25.3.: Adventures in Proteomics (prof. RNDr. Zbyněk Zdráhal, Dr.)
  • 1.4.: Principles for Studying the Structure and Dynamics of Proteins and Nucleic Acids Using NMR Spectroscopy (doc. RNDr. Radovan Fiala, CSc.)
  • 8.4.: Determination of Protein and Macromolecular Structures by X-ray Crystallography (Mgr. Josef Houser, Ph.D.)
  • 15.4.: Principles of Electron Microscopy and Its Applications in Biology (Mgr. Jiří Nováček, Ph.D.)
  • 22.4.: In Silico Methods for Determining Biomolecular Structures (doc. RNDr. Radka Svobodová, Ph.D.)
  • 29.4.: Light Microscopy (Mgr. Milan Ešner, Ph.D.)
  • 6.5.: Atomic Force Microscopy (Mgr. Jan Přibyl, Ph.D.)
  • 13.5.: MUNI DAY
  • 20.5. : Available replacement date
Approaches, practices, and methods used in teaching
lectures, class discussion
Method of verifying learning outcomes and course completion requirements
The course will be concluded with a colloquium, which can take one of two forms: either a discussion on a selected topic or the submission of a seminar thesis focusing on one or more methods introduced in the course.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
The course is also listed under the following terms spring 2025.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/cus/spring2026/CORE126