LF:ZLIM051c Immunology in Dent. - pract. - Course Information

ZLIM051c Immunology in Dentistry- practice

Extent and Intensity

0/1/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching

Teacher(s)

prof. MUDr. Jiří Litzman, CSc. (seminar tutor)
doc. MUDr. Zita Chovancová, Ph.D. (seminar tutor)
Miroslava Bučková (assistant)

Guaranteed by

prof. MUDr. Jiří Litzman, CSc.
Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: prof. MUDr. Jiří Litzman, CSc.
Supplier department: Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine

Timetable

Tue 16. 9. 14:00–15:40 I.CHK N01001, Tue 23. 9. 14:00–15:40 I.CHK N01001, Tue 30. 9. 14:00–15:40 I.CHK N01001, Tue 7. 10. 14:00–15:40 I.CHK N01001, Tue 14. 10. 14:00–15:40 I.CHK N01001, Tue 21. 10. 14:00–15:40 I.CHK N01001, Tue 4. 11. 14:00–15:40 I.CHK N01001, Tue 11. 11. 14:00–15:40 I.CHK N01001, Tue 18. 11. 14:00–15:40 I.CHK N01001, Tue 25. 11. 14:00–15:40 I.CHK N01001, Tue 2. 12. 14:00–15:40 I.CHK N01001, Tue 9. 12. 14:00–15:40 I.CHK N01001, Tue 16. 12. 14:00–15:40 I.CHK N01001

Prerequisites (in Czech)

( ZLBC0221p Biochemistry I - lecture || ZLBC0321p Biochemistry I - lecture ) && ZLFY0422c Physiology II - practice && ZLFY0422s Physiology II - seminar && ZLLM0421c Med.Oral Microbiol.I-pract.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Dentistry (programme LF, M-ZL) (2)

Abstract

The course is focused to clinical and laboratory aspects of immunology in medicine. After finishing this course the student will understand the pathogenesis of immunopathological diseases and know the clinical manifestation and the treatment approaches to the most severe disturbances of the immune system particularly focused on the orofacial localization.

Learning outcomes

After finishing this course the student will understand the pathogenesis of immunopathological diseases and know the clinical manifestation and the treatment approaches to the most severe disturbances of the immune system particularly focused on the orofacial localization.

Key topics

**November 6** Immunology: Historical development, current state, the role of immunology in medicine. The immune system as a physiological and pathogenetic principle. Basic characteristics of innate and adaptive immunity. Regionalization of immune responses, common mucosal immune system. Antigen-antibody reactions in vitro as the basis of immunological examination methods. **November 13** Cellular basis of the immune system: Primary and secondary lymphoid organs. Subpopulations of T, B, and NK lymphocytes. Professional phagocytes. Other cells involved in immune responses. Humoral components of immunity: Cytokines. Complement system. Immunoglobulins, biological properties of individual classes (IgG, A, M, E, D). Polyclonal and monoclonal antibodies (preparation, diagnostic and therapeutic use). **November 20** Inflammation as a complex reaction of the innate immune system. Induction and development of adaptive immune responses (antibody production, cellular immunity). Immunological memory. Immunological tolerance. **November 27** Anti-infectious immunity. Vaccines and vaccination. Immunoglobulin preparations. Mechanisms of innate and adaptive immunity in the oral cavity. Secretory IgA. Immunological aspects of dental caries. **December 4** Immunopathology with a focus on manifestations in the orofacial region. Primary and secondary immunodeficiencies. Oral manifestations of HIV and AIDS infections. Immunological hypersensitivity. Common allergic diseases. Food allergies. Drug allergies. Anaphylactic shock. **December 11** Organ-specific and systemic autoimmune diseases. Manifestations of autoimmune diseases in the oral cavity. Sjögren's syndrome. Immunology of periodontal diseases. The importance of microorganisms, immunogenetic predispositions, mechanisms of damage and repair. Antitumor immunity. Possibilities of immunological diagnostics and therapy. **December 18** Immunological aspects of transplantation, blood transfusions, and reconstructive medicine. Immunosuppressive therapy: indications, methods, risks. Possibilities of supporting and stimulating the immune system. Indications and interpretation of laboratory immunological examinations.

Study resources and literature

recommended literature
• HOŘEJŠÍ, Václav; Jiřina BARTŮŇKOVÁ; Tomáš BRDIČKA and Radek ŠPÍŠEK. Základy imunologie. 6., aktualizované vydání. V Praze: Stanislav Juhaňák - Triton, 2017, 297 stran. ISBN 9788075532503. info
• LITZMAN, Jiří; Tomáš FREIBERGER; Vlastimil KRÁL and Vojtěch THON. Základy vyšetření v klinické imunologii (Investigations in clinical immunology). 2. dotisk 1. vyd. Brno: Masarykova univerzita, 2011, 53 pp. ISBN 978-80-210-4227-8. info

Approaches, practices, and methods used in teaching

practice

Method of verifying learning outcomes and course completion requirements

To get the credit active presence on seminars is required.

Language of instruction

Czech

Further Comments

The course is taught annually.

• Enrolment Statistics (recent)
  
• Permalink: https://is.muni.cz/course/med/autumn2025/ZLIM051c