ZLLC011p Medical Chemistry, Dental Materials - lecture

Faculty of Medicine
autumn 2022
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught in person.
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (assistant)
PharmDr. Jiří Kos, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (assistant)
Mgr. Jindra Smutná, Ph.D. (assistant)
Bc. Ivana Ševčíková (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
doc. RNDr. Jiří Dostál, CSc. (alternate examiner)
RNDr. Hana Paulová, CSc. (alternate examiner)
Mgr. Jiří Slanina, Ph.D. (alternate examiner)
prof. RNDr. Eva Táborská, CSc. (alternate examiner)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Marie Tomandlová, Ph.D.
Supplier department: Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Wed 14. 9. 7:30–9:10 B11/114, Wed 12. 10. 7:30–9:10 B11/114, Wed 26. 10. 7:30–9:10 B11/114, Wed 9. 11. 7:30–9:10 B11/114, Wed 23. 11. 7:30–9:10 B11/114, Wed 7. 12. 7:30–9:10 B11/114
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to provide knowledge of chemistry, which is necessary for the understanding of chemical principles applied in other subjects, especially in biochemistry. The student will learn about the properties of the solutions, and general physicochemical laws. The properties of elements and compounds of importance in medicine, nutrition and toxicology are presented. The subject should also provide an overview of the compounds and reactions involved in metabolism and toxicologically relevant organic compounds. Information on the composition and chemical substance of the main materials used in dentistry is presented.
Learning outcomes
Students will be able to understand basics of general, inorganic and organic chemistry to the extent necessary for the further study of biochemistry.
They will be able to apply general physicochemical laws to processes in living organisms.
They will be able to describe the chemical properties of the most important biogenic elements and essential compounds of importance in medicine, nutrition and toxicology. They will be able to describe and discuss the properties and reactions of organic and bioorganic compounds important for the understanding of biochemical processes.
They will be able to describe and discuss the composition and chemical nature of the main materials used in dentistry.
  • Acid base reactions, basic terms, dissociation of electrolytes, buffers, buffer systems in organism.
  • Energetics of chemical reactions, chemical equilibrium, redox reactions, biochemically important redox reactions.
  • Biologically important elememts and their compounds.
  • Biochemically important reactions of organic compounds (e.g. reactions of alcohols, carboxylic acids, transamination, the reactions of citric acid cycle).
  • Structure and properties of carbohydrates, polysaccharides, glycoside, nucleosides.
  • Fatty acids, lipids, fosfolipids, glycolipids, steroids, steroid hormones.
  • Stomatological materials.
    required literature
  • TOMANDL, Josef, Jiří DOSTÁL, Hana PAULOVÁ and Eva TÁBORSKÁ. Základy lékařské chemie a biochemie. 1st ed. Brno: Masarykova Univerzita, 2014. 212 pp. ISBN 978-80-210-6973-2. info
  • VALENTOVÁ, Kateřina. Chemické vlastnosti dentálních materiálů. 2nd ed. Olomouc: UP Olomouc, 2011. 78 pp. skripta. ISBN 978-80-244-2866-6. info
Teaching methods
Teaching form are lectures. Supplementary subjects are seminars and practicals (VSLC011c and VSLC011c).
Assessment methods
Student must have course-unit credit of seminar in the day of exam.
Examination from Medical chemistry is only written. The test consists from two parts.
The first part is solved on computers in the computer room of Department of Biochemistry: calculations (concentration, pH, buffers, osmotic pressure) – see seminars
simple questions (multiple choice or free answer)
structural formulas (essential organic and inorganic compounds).
The second part is written and is focused on the active knowledge of structural formulas of the most important compounds, expression of important biochemical reactions by chemical equations and the ability to formulate the basic physico-chemical relationships or to draw graphs. For detailed instructions see Study materials - Information about exam.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses

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The course is also listed under the following terms Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021.
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