CS

LF:VLFA0621c Pharmacology I - p - Course Information

VLFA0621c Pharmacology I - practice

Faculty of Medicine
Spring 2010
Extent and Intensity
0/3/0. 5 credit(s). Type of Completion: z (credit).
Teacher(s)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
MUDr. Mgr. Karel Šlais, Ph.D. (seminar tutor)
MVDr. Dagmar Vršková, Ph.D. (seminar tutor)
PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
doc. PharmDr. Jana Rudá, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Supervisor
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: prof. MUDr. Alexandra Šulcová, CSc.
Timetable of Seminar Groups
VLFA0621c/01: Wed 7:30–10:00 N03206/206
VLFA0621c/02: Wed 7:30–10:00 N03206/206
VLFA0621c/03: Wed 10:20–12:50 N03206/206
VLFA0621c/04: Wed 10:20–12:50 N03206/206
VLFA0621c/05: Fri 7:30–10:00 N03206/206
VLFA0621c/06: Fri 7:30–10:00 N03206/206
VLFA0621c/07: Fri 10:20–12:50 N03206/206
VLFA0621c/08: Fri 10:20–12:50 N03206/206
VLFA0621c/09: Mon 7:30–10:00 N03206/206
VLFA0621c/10: Mon 7:30–10:00 N03206/206
VLFA0621c/11: Mon 10:20–12:50 N03206/206
VLFA0621c/12: Mon 10:20–12:50 N03206/206
VLFA0621c/13: Tue 7:30–10:00 N03206/206
VLFA0621c/14: Tue 7:30–10:00 N03206/206
VLFA0621c/15: Tue 10:20–12:50 N03206/206
VLFA0621c/16: Tue 10:20–12:50 N03206/206
VLFA0621c/17: Thu 7:30–10:00 N03206/206
VLFA0621c/18: Thu 7:30–10:00 N03206/206
VLFA0621c/19: Thu 10:20–12:50 N03206/206
VLFA0621c/20: Thu 10:20–12:50 N03206/206
VLFA0621c/30A: No timetable has been entered into IS.
VLFA0621c/30B: No timetable has been entered into IS.
VLFA0621c/31: No timetable has been entered into IS.
Prerequisites (in Czech)
VSPF0521c Pathophysiol. I - practice. && VSPA0521c Pathology - practicals
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
Fields of study the course is directly associated with
Course objectives
On completion of the course the student will be able to use formally correct terminology belonging to the valid Pharmacopoea in prescription and making of drug dosage forms of both individually prepared and bulk preparations. The student should be able to understand principles of "pharmacological thinking" for choosing a drug, dosing regimen, pharmacokinetic parameter calculation, differences in administration routes and specifics of pediatric and geriatric pharmacotherapy including possible impact of drug-drug interactions.
Syllabus
  • 1. week (22.2.-26.2.)
  • Topic: INTRODUCTION TO THE STUDY OF PHARMACOLOGY
  • Course content: Organisation of practical courses and lectures. Recommended textbooks. Pharmacological calculations. Introduction to latin terminology used in drug prescription. Pharmacopoea.
  • Getting ready for next lesson: Repetition of latin terminology.
  • 2. week (1.3.-5.3.)
  • Topic: GENERAL RULES OF THE DRUG PRESCRIPTION
  • Course content: Drug prescriptions: Elements of the drug prescription. Prescription of individual and manufactured preparations. Legislation of drug prescription. Prescription of narcotic and psychotropic agents. Drug incompatibilities. Drug dosology in paediatrics. Getting ready for next lesson: Repetition of latin terminology, general rules of drug prescrition.
  • 3. week (8.3.-12.3.)
  • Topic: SOLID DRUG DOSAGE FORMS.
  • Course content: Powders for external and internal use, capsules, tablets, teas - composition, prescription, suppositories. Terminology, classification. Video-programme: Industrial production of solid drug forms. Getting ready for next lesson: Calculations in pharmacology.
  • REVISING TEST: LATIN TERMINOLOGY AND ABBREVIATIONS, BASICS OF PRESCRIPTION AND BASIC TERMS.
  • 4. week (15.3.-19.3.)
  • Topic: FLUID DRUG DOSAGE FORMS FOR FOR THE EXTERNAL USE, ORAL AND PARENTERAL USE.
  • Course content: Application and rinse solutions; eye, ear and nose lotions, suspensions - composition and prescription. Solutions for oral administration, drops and tinctures, injections and intravenous infusions.
  • Video-programme: Ready-made solutions for injection and infusion. Getting ready for next lesson: Latin names of adjuvants.
  • 5. week (22.3.-26.3.)
  • Topic: SOFT, MELTING AND GASEOUS DRUG DOSAGE FORMS
  • Course content: Ointments, pastes, plasters - composition and prescription.
  • Video-programme: External preparations.
  • Getting ready for next lesson: Repetition of general prescription.
  • Please bring white lab-coats with you!
  • 6. week (29.3.-2.4.)
  • Topic: PRACTICAL SELF-PREPARATION OF SELECTED DRUG DOSAGE FORMS.
  • Course content: Individual preparation of the selected dosage forms (capsules, suppositorias, ointments...)
  • Getting ready for next lesson: Please bring white lab-coats with you!
  • REVISING TEST: GENERAL PRESCRIPTION.
  • 7. week (5.4.-9.4.)
  • Topic: INTRODUCTION TO EXPERIMENTAL PHARMACOLOGY
  • Course content: Pharmacological experiments. Laboratory animals. Protocol. Methods used in pre-clinical experiments.
  • Video-programme: Laboratory animals handling.
  • Getting ready for next lesson: Transport of drugs across biological barriers.
  • 8. week (12.4.-16.4.)
  • Topic: INTRODUCTION TO THE PHARMACOKINETICS.
  • Course content: Basic pharmacokinetic processes and parameters. One- and two-compartment kinetic models. Kinetics of the intravascular and extravascular drug administration. Practical pharmacokinetic calculations.
  • Getting ready for next lesson: Pharmacokinetic calculations. Please bring ruler and calculator with you!
  • 9. week (19.4.-23.4.)
  • Topic: PRACTICAL PHARMACOKINETIC COMPUTATIONS.
  • Course content: Computer technique in pharmacokinetics. Calculations of the basic pharmacokinetic parameters: Work with PC: software MW PHARM. Therapeutic drug monitoring.
  • Getting ready for next lesson: Repetition of anatomy and physiology of peripheral nervous system.
  • 10. week (26.4.-30.4.)
  • Topic: PHARMACOLOGY OF THE AUTONOMIC NERVOUS SYSTEM-CHOLINOMIMETICS.
  • Course content: Terminology, receptors, agonists and antagonists, pharmacological control of autonomic functions.
  • Video-programme: Cholinergic transmission.
  • 11. week (3.5.-7.5.)
  • Topic: PHARMACOLOGY OF THE SYMPATHETIC NERVOUS SYSTEM.
  • Course content: Adrenergic receptors, adrenoceptor-activating and adrenoceptor-blocking drugs.
  • Video-programme: Beta-adrenergic receptors.
  • 12. week (10.5.-14.5.)
  • Topic: ANTISEPTICS, DISINFECTANS, DERMATOLOGICS, OPHTHALMOLOGICS, ORL DRUGS
  • Course content: Drugs used in dermatology, surgery, otorhinolaryngology, ophthalmology and their prescription.
  • Getting ready for next lesson: Next lesson in botanical garden on Údolní street!
  • 13. week (17.5.-21.5.)
  • Topic: EXCURSION TO THE CENTRE OF MEDICINAL PLANTS.
  • 14. week (10.5.-14.5.)
  • Topic: PHARMACOLOGY OF MEDICINAL PLANTS.
  • Course content: History, classification and chemistry of plant drugs, their practical medicinal use.
  • FINAL REVISION TEST
  • CREDITS.
Literature
    required literature
  • LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007. xxiv, 672. ISBN 9788072623730. info
  • HADAŠOVÁ, Eva, Jana NOVÁKOVÁ, Jana PISTOVČÁKOVÁ, Jana VINKLEROVÁ, Alexandra ŠULCOVÁ and Olga STAROBOVÁ. Praktická cvičení z farmakologie (Practical lessons on pharmacology). 2. opravené a doplněné vyd. Brno: Vydavatelství MU Brno-Kraví Hora, 2003. 110 pp. Skripta. ISBN 80-210-2694-4. info
  • http://portal.med.muni.cz/clanek-461-farmakovigilance-a-propagace-leciv.html
    recommended literature
  • DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006. 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
  • http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
  • https://is.muni.cz/auth/el/1411/podzim2008/ZLFA0722p/um/Zasady_antibioticke_ lecby.pdf?fakulta=1411;obdobi=4343;kod=ZLFA0722p
  • RANG, H. P. Rang and Dale's pharmacology. 6th ed. [S.l.]: Churchill Livingstone, 2007. xiii, 829. ISBN 9780443069116. info
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmaceutical Practice, 3rd Ed. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone, 2004, ISBN 0443 07206 X
  • HOWLAND, Richard D. and Mary Julia MYCEK. Pharmacology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2006. vii, 552. ISBN 0781741181. info
  • https://is.muni.cz/auth/el/1411/jaro2009/VLFA0621c/um/Practicals_in_Pharmacology_ENGL.pdf?fakulta=1411;obdobi=4504;kod=VLFA0621c
Teaching methods
Practicals, the teaching process of include theoretical setting up as well as practical training of knowledge and skills stated in Syllabus. Included are also individual work with specific pharmacological softwares and homeworks on the selected topics, presented and discussed afterward in class.
Assessment methods
The participation in practicals is obligatory and registered. To get a credits a student has to pass 3 written tests: a) on Latin terminology (assessed individually by the teacher), b) on drug prescription (assessed individually by the teacher), c) multiple-choice test on knowledge of topics taught (more than half correctly answered questions required).
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017.
  • Enrolment Statistics (Spring 2010, recent)
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