VLLP0431c Clinical Introduction I - practice

Faculty of Medicine
spring 2021
Extent and Intensity
0/1.3/0. 3 credit(s). Type of Completion: z (credit).
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
MUDr. Lenka Gescheidtová (seminar tutor)
MUDr. Miroslava Hlaváčová, Ph.D. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
MUDr. RNDr. Michal Řiháček (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. MUDr. Miroslav Souček, CSc. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Mgr. Martina Drabinová (assistant)
Zdeňka Dvořáková (assistant)
Mgr. Jana Gregorová, Ph.D. (assistant)
PharmDr. Katarína Kostolanská (assistant)
Mgr. Ondřej Peš, Ph.D. (assistant)
Mgr. Jindra Smutná, Ph.D. (assistant)
Monika Šudáková (assistant)
Guaranteed by
MUDr. Jan Konečný, Ph.D.
First Department of Surgery - Institutions shared with St. Anne's Faculty Hospital - Faculty of Medicine
Contact Person: prof. RNDr. Eva Táborská, CSc.
Supplier department: Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLAN0222c Anatomy II p && VLAN0222s Anatomy II s
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course combines theoretical biochemistry knowledge with clinical applications.
  • Biochemical investigations in clinical medicine and their significance. Biochemical analysers, point of care testing. Factors influencing results of laboratory examinations. Blood collection and processing. Laboratory tests in clinical biochemistry. Sources of error, assessing the significance of a test result. System of quality control. Biological and analytical variations, critical difference. Reference intervals. Interpretation of results. Diabetes mellitus - laboratory diagnosis. Hypoglycaemia, hyperglycaemia, screening and monitoring, oGTT test. Glycosuria, fructosamine, haemoglobin, microalbuminuria, insulin, C-peptide, autoantibodies. Biochemical diagnosis of liver diseases. Tests for the integrity of hepatocytes. The tests for hepatocellular cholestasis. Tests of the liver’s biosynthetic capacity. Laboratory diagnosis of jaundice. Laboratory tests of specific liver diseases. Biochemical markers of myocardial injury - cardiac troponin, myoglobin, CK-MB mass. Laboratory tests in heart failure - natriuretic peptides. Tests for homocysteine, hsCRP, lipid spectrum. Sampling and urine collection for physical, chemical, microbiological and microscopic examination. Physical examination of urine (pH, density, osmolality). Chemical examination of urine. Glomerular filtration rate (creatinine, cystatin). Morphological analysis of urine. Examination of urine sediment. Kidney stones analysis – classification of kidney stones according to the composition, factors affecting their formation, methods of analysis. Cerebrospinal fluid (CSF) analysis. Indications, puncture, basic and special examination, typical findings in some neurological diseases, markers of CSF leakage. Investigation of blood count.
    required literature
  • Podklady k seminářům dostupné v Informačním systému
    recommended literature
  • ŠPINAR, Jindřich and Ondřej LUDKA. Propedeutika a vyšetřovací metody vnitřních nemocí. 2., přeprac. a dopl. vyd. Praha: Grada, 2013. 336 pp. ISBN 978-80-247-4356-1. URL info
  • ZEMAN, Miroslav and Zdeněk KRŠKA. Chirurgická propedeutika. Třetí, přepracované a do. Praha: Grada Publishing, 2011. 512 stran. ISBN 9788024737706. info
Teaching methods (in Czech)
Probíhá formou semináře s praktickými vstupy a ukázkami. Studenti dostávají písemné podklady pro přípravu a současně soubor otázek a problémů k řešení. Seminář probíhá aktivní formou, diskuze k zadaným problémům.
Assessment methods
Conditions for giving the course-unit credit * Full (100%) attendance in practice is the principal condition. If any absence, it must be apologized through Department of Study Affairs up to five days. If apology is recorded in Information System (IS), then student is allowed to make up the absence according to teacher's instructions. * Two revision tests are written during the semester, limit for credit is 21points. * If the semestral limit is not fulfilled, student must write the Credit test (limit 9/20). All absences must be made up before writing the credit test. * One repetition of the Credit test is approved.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 19.5.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/spring2021/VLLP0431c