aFAFK3_14 Pharmacology III

Faculty of Pharmacy
Spring 2026

The course is not taught in Spring 2026

Extent and Intensity
3/2/0. 6 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
PharmDr. Tereza Kauerová, Ph.D. (lecturer)
doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
MVDr. Renata Blechová, Ph.D. (seminar tutor)
MUDr. Marta Chalupová, Ph.D. (seminar tutor)
PharmDr. Tereza Kauerová, Ph.D. (seminar tutor)
PharmDr. Bc. Hana Kotolová, Ph.D. (seminar tutor)
PharmDr. Zuzana Široká, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Peter Kollár, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Prerequisites (in Czech)
aFAFK2_14 Pharmacology II
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Learning outcomes
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Key topics
  • - General principles of antimicrobial treatment, mechanisms of resistance to ATB treatment, beta-lactam ATB
  • - Antimicrobial drugs (pharmacological groups of antibacterial drugs)
  • - Antivirals, antifungals
  • - Anti-infective drugs. Antiparasitic, antiprotozoic, antituberculotic, antileprotic drugs
  • - Pharmacology of the heart (antiarrhythmics, positive inotropes and treatment of acute and chronic heart failure)
  • - Pharmacology of essential hypertension
  • - Vascular pharmacology (vasoconstrictors, vasodilators, venotonics)
  • - Blood pharmacology (anemia, influencing blood clotting - anticoagulants, fibrinolytics, hemostatics, antifibrinolytics, antiaggregants, antithrombotics)
  • - Pharmacology of the respiratory system (Antiasthmatics, pharmacotherapy of chronic obstructive pulmonary disease. Cough-antitussive therapy, expectorants)
  • - H1 antihistamines. Antiemetics, prokinetics. Antivertiginosis, drugs used in the therapy of Ménière's disease and tinnitus
  • - Peripheral hormones and mediators (autacoids) and their pharmacological significance (histamine and antihistamines, serotonin, prostaglandins, NO, bradykinin
  • - Medicines affecting the thyroid gland. Pharmacotherapy of osteoporosis and other bone diseases
  • - Medicines used in DM type 1 therapy - Insulin and its analogs. The endocrine pancreas and glycemic control. Insulin therapy, application forms, regimens, acute care, complications
  • - Medicines used in DM type 2 therapy
  • - Hypolipidemics, antiobesitics (Lipid spectrum disorder, Atherosclerotic cardiovascular disease, cardiorenal syndrome)
  • - Pharmacology of female and male sex hormones (agonists, antagonists, contraceptives, hormone replacement therapy)
  • - Mineralocorticoids, glucocorticoids
  • - Immunopharmaceuticals (Immunosuppressants, immunomodulation)
  • - Cytostatics (drugs used in cancer therapy)
  • - Biological treatment and principles of targeted therapy
Study resources and literature
    required literature
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
    recommended literature
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Approaches, practices, and methods used in teaching
lectures, seminars
Method of verifying learning outcomes and course completion requirements
Continusous and final written test, oral examination
Language of instruction
English
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