C6219 Clinical Biochemistry

Faculty of Science
Autumn 2025
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
prof. RNDr. Michaela Wimmerová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Michaela Wimmerová, Ph.D.
Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 11:00–12:50 B11/205
Prerequisites (in Czech)
( C4182 Biochemistry II || C3580 Biochemistry || C5720 Biochemistry ) && (! C6221 Clinical Biochemistry ) && (! C6220 Clinical Biochemistry ) && !NOWANY( C6221 Clinical Biochemistry )
předpokládá se absolvování základní přednášky z biochemie a znalost základních metabolických drah na úrovni buňky.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
The goal of this course is to provide general basic knowledge about biochemical and molecular aspects of pathobiological processes and to understand analytes in clinical biochemistry diagnostics.

At the end of the course students should be able to:
understand the basic physiological events in healthy human organism;
understand and explain relationships between analytical parameters determined in clinical biochemistry laboratories ans their diagnostic indication;
Learning outcomes
Student will be able to understant basic function of human organism in relation with the commonly used biochemical markers connected with clinical biochemistry diagnostics
Key topics
  • Body water and electrolytes
  • Renal function
  • Acid-base control and acid-base disorders
  • Liver function
  • Diabetes mellitus
  • Disorders of lipid and lipoprotein metabolism
  • Gastrointestinal function, pancreatic function, digestive disease
  • Bone disease
  • Biochemistry of muscle
  • Inborn errors of metabolism
Study resources and literature
  • Jaroslav Racek a kol. Klinická biochemie. 2006. info
  • RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1st ed. Praha: Galén, 1999, 316 pp. ISBN 80-7262-023-1. info
  • MASOPUST, Jaroslav. Klinická biochemie. Požadování a hodnocení biochemických vyšetření. (Clinical chemistry.). 1st ed. Praha: Karolinum, 1998, 832 pp. část I. a část II. ISBN 80-7184-649-3. info
  • KARLSON, Peter; Wolfgang GEROK and W. GROSS. Pathobiochemie. 1. vyd. Praha: Academia, 1987, 480 s. info
Approaches, practices, and methods used in teaching
lectures
Method of verifying learning outcomes and course completion requirements
written exam
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2025/C6219