C6222 Clinical Biochemistry II

Faculty of Science
Spring 2023
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Taught in person.
prof. RNDr. Michaela Wimmerová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Michaela Wimmerová, Ph.D.
Department of Biochemistry - Chemistry Section - Faculty of Science
Contact Person: prof. RNDr. Michaela Wimmerová, Ph.D.
Supplier department: Department of Biochemistry - Chemistry Section - Faculty of Science
Wed 10:00–11:50 B11/335
Prerequisites (in Czech)
( PROGRAM ( B - LGM ) && C6219 Clinical Biochemistry ) || ( PROGRAM ( N - BIC ) && ( C6220 Clinical Biochemistry || C6221 Clinical Biochemistry ))
Předpokládá se absolvování základní přednášky z biochemie, znalost základních metabolických drah na úrovni buňky a absolvování předmětu Klinická biochemie I. (C6219 nebo C6221). Studenti programu Biochemie si zapisují v magisterském studiu.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of this course is to provide general basic knowledge about biochemical and molecular aspects of pathobiological processes and use of biochemical tests to obtain diagnostic information. The course is focused mainly on analytical aspects and methods in in clinical biochemistry.

At the end of the course students should be able to:
understand the basic physiological events in healthy human organism;
understand and explain relationships between analytical parameters determined in clinical biochemistry laboratories ans their diagnostic indication;
interpret basic non-physiological results and give them into a context of the potential disease
Learning outcomes
Student will be able to - understant basic function of human organism in relation with the commonly used biochemical markers connected with clinical biochemistry diagnostics - describe basic methods used in clinical biochemistry laboratories
  • Laboratory techniques
  • Basic laboratory principles and calculations
  • Collection and handling of patient specimens
  • Methods in clinical biochemistry
  • Analysis of metabolites, proteins and enzymes
  • Automation
  • Laboratory statistics, reference values, quality control
  • Evaluation of methods
  • DASTYCH, Milan. Klinická biochemie : bakalářský obor Zdravotní laborant. 1. dotisk 3. vyd. Brno: Masarykova univerzita, 2021. ISBN 978-80-210-7788-1. info
  • RACEK, Jaroslav. Klinická biochemie. 2., přeprac. vyd. Praha: Galén, 2006. 329 s. ISBN 8072623249. info
  • ZIMA, Tomáš. Laboratorní diagnostika. 1. vyd. Praha: Galén, 2002. xxxii, 728. ISBN 8072622013. info
  • RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1st ed. Praha: Galén, 1999. 316 pp. ISBN 80-7262-023-1. info
  • MASOPUST, Jaroslav. Klinická biochemie. Požadování a hodnocení biochemických vyšetření. (Clinical chemistry.). 1st ed. Praha: Karolinum, 1998. 832 pp. část I. a část II. ISBN 80-7184-649-3. info
  • Clinical biochemistry :metabolic and clinical aspects. Edited by S. K. Bangert - William J. Marshall. New York: Churchill Livingstone, 1995. xi, 854 s. ISBN 0-443-04341-8. info
  • Clinical guide to laboratory tests. Edited by Norbert W. Tietz. 3rd ed. Philadelphia: W.B. Saunders Company, 1995. xxxix, 109. ISBN 0-7216-5035-X. info
  • KARLSON, Peter, Wolfgang GEROK and W. GROSS. Pathobiochemie. 1. vyd. Praha: Academia, 1987. 480 s. info
Teaching methods
Assessment methods
written exam
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.

  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/spring2023/C6222