Výpis publikací

HLUCHÝ, Milan a Dalibor BLAŽEK. CDK11, a splicing-associated kinase regulating gene expression. Trends in Cell Biology. Cell Press, 2024. ISSN 0962-8924. Dostupné z: https://dx.doi.org/10.1016/j.tcb.2024.08.004.

BLAŽEK, Dalibor a Kamil PARUCH. Nové látky, které inhibují CDK11, nalezené na základě sreeningu knihovny nízkomolekulárních látek a cílené syntézy. 2024.

BLAŽEK, Dalibor a Kamil PARUCH. Preklinický vývoj inhibitorů CDK11 - identifikace látek vhodných pro patentovou ochranu a komercializaci. 2024.

LUKAVSKY, Peter, Dalibor BLAŽEK, Vojtěch BYSTRÝ, Anna HELÁNOVÁ a Barbora TRUKSOVÁ. RNA Summer School 2023. 2023.

BLAŽEK, Dalibor. Therapeutic potential of CDK11 in cancer. CLINICAL AND TRANSLATIONAL MEDICINE. ENGLAND: JOHN WILEY & SONS LTD, 2023, roč. 13, č. 3, s. 1-4. ISSN 2001-1326. Dostupné z: https://dx.doi.org/10.1002/ctm2.1201.

HLUCHÝ, Milan, Pavla GAJDUŠKOVÁ, Igor RUIZ DE LOS MOZOS, Michal RÁJECKÝ, Michael KLUGE, Benedict-Tilman BERGER, Zuzana SLABÁ, David POTĚŠIL, Elena WEISS, Jernej ULE, Zbyněk ZDRÁHAL, Stefan KNAPP, Kamil PARUCH, Caroline C. FRIEDEL a Dalibor BLAŽEK. CDK11 regulates pre-mRNA splicing by phosphorylation ofSF3B1. NATURE. ENGLAND: NATURE PORTFOLIO, 2022, roč. 609, č. 7928, s. 829-834. ISSN 0028-0836. Dostupné z: https://dx.doi.org/10.1038/s41586-022-05204-z.

GAJDUŠKOVÁ, Pavla, I.R. DE LOS MOZOS, Michal RÁJECKÝ, Milan HLUCHÝ, J. ULE a Dalibor BLAŽEK. CDK11 is required for transcription of replication-dependent histone genes. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2020, roč. 27, č. 5, s. 500-510, 33 s. ISSN 1545-9993. Dostupné z: https://dx.doi.org/10.1038/s41594-020-0406-8.

PILAŘOVÁ, Květa, Jan HERUDEK a Dalibor BLAŽEK. CDK12: cellular functions and therapeutic potential of versatile player in cancer. NAR Cancer. 2020, roč. 2, č. 1. ISSN 2632-8674. Dostupné z: https://dx.doi.org/10.1093/narcan/zcaa003.

HLUCHÝ, Milan, David POTĚŠIL, Zbyněk ZDRÁHAL a Dalibor BLAŽEK. Identification of CDK11 interactome. In CEITEC PhD Conference. 2020.

CHIRACKAL MANAVALAN, Anil Paul, Květa PILAŘOVÁ, Michael KLUGE, Koen BARTHOLOMEEUSEN, Michal RÁJECKÝ, Jan OPPELT, PrashantKumar KHIRSARIYA, Kamil PARUCH, Lumír KREJČÍ, Caroline C FRIEDEL a Dalibor BLAŽEK. CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes. EMBO reports. Hoboken: Wiley-Blackwell, 2019, roč. 20, č. 9, s. 1-29. ISSN 1469-221X. Dostupné z: https://dx.doi.org/10.15252/embr.201847592.

CHIRACKAL MANAVALAN, Anil Paul, Květa PILAŘOVÁ, M. KLUGE, Koen BARTHOLOMEEUSEN, Jan OPPELT, PrashantKumar KHIRSARIYA, Kamil PARUCH, Lumír KREJČÍ, C. FRIEDEL a Dalibor BLAŽEK. CDK12 kinase activity controls G1/S progression by regulating optimal transcription of core DNA replication genes. In 2018 ASCB | EMBO Annual Meeting. 2018.

GREIFENBERG, Ann Katrin, Dana HÖNIG, Květa PILAŘOVÁ, Robert DÜSTER, Koen BARTHOLOMEEUSEN, Christian A. BOSKEN, Kanchan ANAND, Dalibor BLAŽEK a Matthias GEYER. Structural and Functional Analysis of the Cdk13/Cyclin K Complex. Cell Reports. CAMBRIDGE: Cell Press, 2016, roč. 14, č. 2, s. 320-331. ISSN 2211-1247. Dostupné z: https://dx.doi.org/10.1016/j.celrep.2015.12.025.

BLAŽEK, Dalibor, Fernando TEQUE, Carl MACKEWICZ, Matija PETERLIN a Jay A. LEVY. The CD8+cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+cells. Journal of General Virology. Reading: Society of General Microbiology, 2016, roč. 97, January, s. 220-224. ISSN 0022-1317. Dostupné z: https://dx.doi.org/10.1099/jgv.0.000326.

EKUMI, Kingsley M., Hana PACULOVÁ, Tina LENASI, Vendula POSPÍCHALOVÁ, Christian A. BOESKEN, Jana RYBAŘÍKOVÁ, Vítězslav BRYJA, Matthias GEYER, Dalibor BLAŽEK a Matjaz BARBORIC. Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. Nucleic Acids Research. Oxford, UK: Oxford University Press, 2015, roč. 43, č. 5, s. 2575-2589. ISSN 0305-1048. Dostupné z: https://dx.doi.org/10.1093/nar/gkv101.

BÖSKEN, Christian A., Lucas FARNUNG, Corinna HINTERMAIR, Miriam Merzel SCHACHTER, Karin VOGEL- BACHMAYR, Dalibor BLAŽEK, Kanchan ANAND, Robert P. FISHER, Dirk EICK a Matthias GEYER. The structure and substrate specificity of human Cdk12/Cyclin K. NATURE COMMUNICATIONS. London: Nature Publishing Group, 2014, roč. 5, č. 3505, s. "nestránkováno", 14 s. ISSN 2041-1723. Dostupné z: https://dx.doi.org/10.1038/ncomms4505.

ŠMERDOVÁ, Lenka, Jana SVOBODOVÁ, Markéta KABÁTKOVÁ, Jiří KOHOUTEK, Dalibor BLAŽEK, Miroslav MACHALA a Jan VONDRÁČEK. Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway. Carcinogenesis. Oxford: Oxford University Press, 2014, roč. 35, č. 11, s. 2534-2543. ISSN 0143-3334. Dostupné z: https://dx.doi.org/10.1093/carcin/bgu190.

KOHOUTEK, Jiří a Dalibor BLAŽEK. Cyclin K goes with Cdk12 and Cdk13. Cell Division. London: Biomed Central Ltd., 2012, roč. 7, č. 12, s. "nestránkováno", 10 s. ISSN 1747-1028. Dostupné z: https://dx.doi.org/10.1186/1747-1028-7-12.

BLAŽEK, Dalibor. The cyclin K/Cdk12 complex An emerging new player in the maintenance of genome stability. Cell Cycle. AUSTIN: LANDES BIOSCIENCE, USA, 2012, roč. 11, č. 6, s. 1049-1050. ISSN 1538-4101. Dostupné z: https://dx.doi.org/10.4161/cc.11.6.19678.

BLAŽEK, Dalibor, Jiří KOHOUTEK, Koen BARTHOLOMEEUSEN, Eric JOHANSEN, Petra HULINKOVÁ, Zeping P. LUO, Peter CIMERMANCIC, Jernej ULE a Matija B. PETERLIN. The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. Genes & Development. Spojené státy americké: Cold Spring Harbor Laboratory Press, 2011, roč. 25, č. 20, s. 2158-2172. ISSN 0890-9369. Dostupné z: https://dx.doi.org/10.1101/gad.16962311.

KOHOUTEK, Jiří, Qintong LI, Dalibor BLAŽEK, Zeping LUO, Huimin JIANG a B Matija PETERLIN. Cyclin T2 Is Essential for Mouse Embryogenesis. Molecular and Cellular Biology. Washington, D.C.: ASM, 2009, roč. 29, č. 12, s. 3280-3285. ISSN 0270-7306. Dostupné z: https://dx.doi.org/10.1128/MCB.00172-09.

BLAŽEK, Dalibor a B Matija PETERLIN. Tat-SIRT1 tango. Molecular Cell. CAMBRIDGE: CELL PRESS, 2008, roč. 29, č. 5, s. 539-540. ISSN 1097-2765. Dostupné z: https://dx.doi.org/10.1016/j.molcel.2008.02.007.

KOHOUTEK, Jiří, Dalibor BLAŽEK a B Matija PETERLIN. Hexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters. Proceedings of the National Academy of Sciences of the United States of America. WASHINGTON: NATL ACAD SCIENCES, 2006, roč. 103, č. 46, s. 17349-17354. ISSN 0027-8424. Dostupné z: https://dx.doi.org/10.1073/pnas.0603079103.

SCHULTE, Antje, Nadine CZUDNOCHOWSKI, Matjaz BARBORIC, Anrdé SCHONICHEN, Dalibor BLAŽEK, B Matija PETERLIN a Matthias GEYER. Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2005, roč. 280, č. 26, s. 24968-24977. ISSN 0021-9258. Dostupné z: https://dx.doi.org/10.1074/jbc.M501431200.

BARBORIC, Matjaz, Jiří KOHOUTEK, Jason P PRICE, Dalibor BLAŽEK, David H PRICE a B Matija PETERLIN. Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb. EMBO Journal. NEW YORK: NATURE PUBLISHING GROUP, 2005, roč. 24, č. 24, s. 4291-4303. ISSN 0261-4189. Dostupné z: https://dx.doi.org/10.1038/sj.emboj.7600883.

BLAŽEK, Dalibor, Matjaz BARBORIC, Jiří KOHOUTEK, Irena OVEN a B Matija PETERLIN. Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb. Nucleic Acids Research. Oxford, UK: Oxford Press, 2005, roč. 33, č. 22, s. 7000-7010. ISSN 0305-1048. Dostupné z: https://dx.doi.org/10.1093/nar/gki997.