Výpis publikací

OTEVŘEL, Jan; David ŠVESTKA; Pavel BOBÁĽ a Mario WASER. Asymmetric organocatalyzed transfer hydroxymethylation of isoindolinones using formaldehyde surrogates. In 53. Syntéza a analýza léčiv, Kurdějov, Česká republika. 2025. ISBN 978-80-280-0773-7.

DRÁPALOVÁ, Monika; David ŠVESTKA a Jan OTEVŘEL. DEVELOPMENT OF ASYMMETRIC MANNICH REACTION OF 2- SUKCCINIMIDYL, 2-GLUTARIMIDYL CARBOXYLATES AND RELATED COMPOUND. In Student Scientific Conference MUNI PHARM, Brno, ČR. 2025.

DRÁPALOVÁ, Monika; David ŠVESTKA a Jan OTEVŘEL. DEVELOPMENT OF ASYMMETRIC MANNICH REACTION OF 2- SUKCCINIMIDYL, 2-GLUTARIMIDYL CARBOXYLATES AND RELATED COMPOUNDS. In XXIII. INTERNATIONAL STUDENTS SCIENTIFIC CONFERENCE, Praha, ČR. 2025.

PUSTĚJOVSKÝ, Adam; David ŠVESTKA a Jan OTEVŘEL. Stereoselective michael addition of benzo[b]thiophene-1,1-dioxide derivatives. In 53. Syntéza a analýza léčiv, Kurdějov, Česká republika. 2025. ISBN 978-80-280-0773-7.

ŠVESTKA, David; Pavel BOBÁĽ a Jan OTEVŘEL. SYNTHESIS OF CHIRAL EXOCYCLIC AMIDINES VIA TANDEM REDUCTION/CYCLIZATION CASCADE USING SODIUM BIS(2- METHOXYETHOXY)ALUMINIUM HYDRIDE. In 53. Konference Syntéza a analýza léčiv, Krudějov, ČR. 2025.

BOBÁĽ, Pavel; Michaela KUCHYNKA; Veronika MURGAŠOVÁ; Eva HAVRÁNKOVÁ; Hana PÍŽOVÁ a Jan OTEVŘEL. 53. Konference Syntéza a analýza léčiv. 2025.

ŠVESTKA, David; Pavel BOBÁĽ; Mario WASER a Jan OTEVŘEL. Asymmetric Organocatalytic Transfer Hydroxymethylation of Isoindolinones Using Formaldehyde Surrogates. In 58th Conference: Advances in Organic, Bioorganic and Pharmaceutical Chemistry – Liblice 2024. 2024.

ŠVESTKA, David; Pavel BOBÁĽ; Mario WASER a Jan OTEVŘEL. Asymmetric Organocatalyzed Transfer Hydroxymethylation of Isoindolinones Using Formaldehyde Surrogates. In ACS PUBLICATIONS SYMPOSIUM Catalysis for Organic Synthesis. 2024.

ŠVESTKA, David; Pavel BOBÁĽ; Jan OTEVŘEL a Mario WASER. Asymmetric Organocatalyzed Transfer Hydroxymethylation of Isoindolinones Using Formaldehyde Surrogates. Organic Letters. Spojené státy: American Chemical Society, 2024, roč. 26, č. 12, s. 2505-2510. ISSN 1523-7060. Dostupné z: https://doi.org/10.1021/acs.orglett.4c00818.

MACEJOVA, Dana; Jakub KOLLAR; Pavel BOBÁĽ; Jan OTEVŘEL; Daniela SCHUSTER a Julius BRTKO. Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer. Molecular and Cellular Biochemistry. DORDRECHT: Springer, 2024, roč. 479, č. 11, s. 3091-3106. ISSN 0300-8177. Dostupné z: https://doi.org/10.1007/s11010-023-04914-w.

ŠVESTKA, David; Pavel BOBÁĽ; Mario WASER a Jan OTEVŘEL. Asymmetric Hydroxymethylation of Isoindolinones Using Bench-Stable Formaldehyde Surrogates. In 57th Conference: Advances in Organic, Bioorganic and Pharmaceutical Chemistry – Liblice 2023. 2023.

OTEVŘEL, Jan. Developing Organocatalysts For Enantioselective Aldol-Type Reactions. In Quo Vadis Chemie? Cyklus přednášek k aktuálním tématům v chemii pořádaný chemickou sekcí PřF UK Praha. 2023.

RIČKO, Sebastijan; René Slot BITSCH; Mikk KAASIK; Jan OTEVŘEL; Mikkel Højgaard MADSEN; Anna KEIMER a Karl Anker JØRGENSEN. Enantioconvergent 6π Electrocyclization Enabled by Photoredox Racemization. Journal of American Chemical Society. Washington, DC: American Chemical Society, 2023, roč. 145, č. 38, s. 20913–20926. ISSN 0002-7863. Dostupné z: https://doi.org/10.1021/jacs.3c06227.

ŠVESTKA, David; Pavel BOBÁĽ; Mario WASER a Jan OTEVŘEL. Enantioselective hydroxymethylation of isoindolinones using bench-stable formaldehyde surrogates. In XXIInd INTERDISCIPLINARY MEETING OF YOUNG LIFE SCIENTISTS. 2023.

OTEVŘEL, Jan; Macarena EUGUI; Sebastijan RIČKO a Karl Anker JØRGENSEN. Enantioselective organocatalytic cycloadditions for the synthesis of medium-sized rings. Nature Synthesis. Nature Publishing Group, 2023, roč. 2, č. 12, s. 1142-1158. ISSN 2731-0582. Dostupné z: https://doi.org/10.1038/s44160-023-00416-1.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Enantioselective trihalohydroxyalkylation of activated phenols. In 57th Advances in Organic, Bioorganic and Pharmaceutical Chemistry Liblice 2023. 2023.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. Asymmetric Organocatalyzed Friedel-Crafts Reaction of Trihaloacetaldehydes and Phenols. Advanced Synthesis and Catalysis. Weinheim: Wiley-VCH GmbH., 2022, roč. 364, č. 13, s. 2174-2183. ISSN 1615-4150. Dostupné z: https://doi.org/10.1002/adsc.202200180.

OTEVŘEL, Jan a Mario WASER. Asymmetric Phase-Transfer Catalysis - From Classical Applications to New Concepts. In Łukasz Albrecht, Anna Albrecht, Luca Dell'Amico. Asymmetric Organocatalysis: New Strategies, Catalysts, and Opportunities. 1. vyd. Weinheim, Germany: WILEY‐VCH GmbH, 2022, s. 71-120. 1. vydání. ISBN 978-3-527-83221-7. Dostupné z: https://doi.org/10.1002/9783527832217.ch3.

ŠVESTKA, David a Jan OTEVŘEL. BENCH-STABLE AND SOLUBLE FORMALDEHYDE SURROGATES IN ASYMMETRIC HYDROXYMETHYLATION OF ISOINDOLINONES. In Student Scientific Conference MUNI Pharm, Doctoral Students 2022. 2022. ISBN 978-80-280-0105-6.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. Enantioselective organocatalyzed trihaloalkylation of activated phenols. In 22nd Tetrahedron Symposium: Catalysis for a Sustainable World. 2022.

HUNAKOVA, L.; E. HORVATHOVA; M. MATUSKOVA; Pavel BOBÁĽ; Jan OTEVŘEL a J. BRTKO. In vitro antiproliferative and cytotoxic activities of novel triphenyltin isoselenocyanate in human breast carcinoma cell lines MCF 7 and MDA-MB-231. Medical Oncology. Cham: Springer Nature, 2022, roč. 39, č. 5, s. 1-9. ISSN 1357-0560. Dostupné z: https://doi.org/10.1007/s12032-022-01692-1.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. PERHALOACETALDEHYDES IN THE ENANTIOSELECTIVE ORGANOCATALYZED FRIDEL-CRAFTS ALKYLATION: REACTION CONDITIONS DEVELOPMENT. In 50th Conference SYNTHESIS AND ANALYSIS OF DRUGS. 2022. ISBN 978-80-280-0110-0.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. Asymmetric Organocatalyzed Friedel-Crafts Reaction of Chloral and Phenols. In Student scientific conference MUNI PHARM 2021. 2021. ISBN 978-80-210-9870-1.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. Asymmetric Organocatalyzed Friedel-Crafts Reaction of Trihaloacetaldehydes and Phenols. In 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry Liblice 2021. 2021.

EITZINGER, A.; Jan OTEVŘEL; V. HAIDER; A. MACCHIA; A. MASSA; K. FAUST; B. SPINGLER; A. BERKESSEL a M. WASER. Enantioselective Bifunctional Ammonium Salt-Catalyzed Syntheses of 3-CF3S-, 3-RS-, and 3-F-Substituted Isoindolinones. ADVANCED SYNTHESIS & CATALYSIS. WEINHEIM: WILEY-V C H VERLAG GMBH, 2021, roč. 363, č. 363, s. 1955-1963. ISSN 1615-4150. Dostupné z: https://doi.org/10.1002/adsc.202100029.

ŠVESTKA, David; Jan OTEVŘEL a Pavel BOBÁĽ. One-pot synthesis of 1-aryl-2-amino alcohols from the corresponding amides or nitriles. In XXth INTERDISCIPLINARY MEETING OF YOUNG RESEARCHERS AND STUDENTS IN THE FIELD OF CHEMISTRY, BIOCHEMISTRY, MOLECULAR BIOLOGY, AND BIOMATERIALS. 2021.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Unexpected formation of 1-aryl-2-aminoalcohols during reductions of the corresponding amides and nitriles. In 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry Liblice 2021. 2021.

STROUHALOVA, D.; D. MACEJOVA; B. MOSNA; Pavel BOBÁĽ; Jan OTEVŘEL; M. LASTOVICKOVA; J. BRTKO a J. BOBALOVA. Down-regulation of vimentin by triorganotin isothiocyanates-nuclear retinoid X receptor agonists: A proteomic approach. Toxicology Letters. CLARE: Elsevier, 2020, roč. 318, č. 318, s. 22-29. ISSN 0378-4274. Dostupné z: https://doi.org/10.1016/j.toxlet.2019.10.004.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. One-pot method for the synthesis of 1-aryl-2-aminoalkanol derivatives from the corresponding amides or nitriles. RSC Advances. Cambridge: Royal Society of Chemistry, 2020, roč. 10, č. 42, s. 25029-25045. ISSN 2046-2069. Dostupné z: https://doi.org/10.1039/d0ra04359a.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Bianthryl-based organocatalysts for the asymmetric Henry reaction of fluoroketones. ORGANIC & BIOMOLECULAR CHEMISTRY. CAMBRIDGE: ROYAL SOC CHEMISTRY, 2019, roč. 17, č. 21, s. 5244-5248. ISSN 1477-0520. Dostupné z: https://doi.org/10.1039/c9ob00884e.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Development of Atropisomeric Organocatalysts for Asymmetric Henry Reaction. In 71. Zjazd chemikov vo Vysokých Tatrách. 2019.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Development of Atropisomeric Organocatalysts for Asymmetric Henry Reaction. In XIX. Interdisciplinary Meeting of Young Life Scientists. 2019.

BOBÁĽ, Pavel a Jan OTEVŘEL. Genotoxic Effects of Tributyltin and Triphenyltin Isothiocyanates, Cognate RXR Ligands: Comparison in Human Breast Carcinoma MCF 7 and MDA-MB-231 Cells. International Journal of Molecular Sciences. 2019. Dostupné z: https://doi.org/10.3390/ijms20051198.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Organocatalyzed asymmetric Henry reaction of fluoroketones. In 54th Advances in Organic, Bioorganic and Pharmaceutical Chemistry Liblice 2019. 2019.

BOBÁĽ, Pavel a Jan OTEVŘEL. Triorganotin derivatives: time-dependent expression of Vimentin, Annexin A5 and selected nuclear receptors mRNA in MDA-MB-231 breast cancer cells. 2019.

OTEVŘEL, Jan a Pavel BOBÁĽ. Triorganotin Isothiocyanates Affect Migration and Immune Check-point Receptors in Human Triple-negative Breast Carcinoma MDA-MB-231 Cells. ANTICANCER RESEARCH. 2019. Dostupné z: https://doi.org/10.21873/anticanres.13670.

OTEVŘEL, Jan a Pavel BOBÁĽ. Effects of selected triorganotin compounds on transcriptional activity of vitamin D-3 receptor and peroxisome proliferator-activated receptor gamma? GENERAL PHYSIOLOGY AND BIOPHYSICS. 2018. Dostupné z: https://doi.org/10.4149/gpb_2018021.

OTEVŘEL, Jan; David ŠVESTKA a Pavel BOBÁĽ. Organocatalyzed Asymmetric Henry Reaction of Alpha-Trifluorinated Acetophenones. 2018. ISBN 978-80-7305-806-7.

OTEVŘEL, Jan a Pavel BOBÁĽ. Triorganotin derivatives induce cell death effects on L1210 leukemia cells at submicromolar concentrations independently of P-glycoprotein expression. MOLECULES. 2018. Dostupné z: https://doi.org/10.3390/molecules23051053.

VETTORAZZI, M; E ANGELINA; S LIMA; Tomáš GONĚC; Jan OTEVŘEL; Pavlína MARVANOVÁ; Tereza PADRTOVÁ; Petr MOKRÝ; Pavel BOBÁĽ; LM ACOSTA; A PALMA; J COBO; Janette BOBÁĽOVÁ; Jozef CSÖLLEI; Ivan MALÍK; S ALVAREZ; S SPIEGEL; J JAMPILEK a RD ENRIZ. An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors. European Journal of Medicinal Chemistry. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, roč. 139, s. 461-481. ISSN 0223-5234. Dostupné z: https://doi.org/10.1016/j.ejmech.2017.08.017.

BOBÁĽ, Pavel a Jan OTEVŘEL. Analysis of proteomic changes in MDA-MB-231 cells induced by selected triorganotin compounds, biologically active ligands of nuclear retinoid X receptors? 2017. Dostupné z: https://doi.org/10.1016/j.toxlet.2017.08.066.

BOBÁĽ, Pavel a Jan OTEVŘEL. Biphenyl-Based Bis(thiourea) Organocatalyst for Asymmetric and syn-Selective Henry Reaction. Synthesis-Stuttgart. 2017. Dostupné z: https://doi.org/10.1055/s-0036-1588594.

BOBÁĽ, Pavel a Jan OTEVŘEL. Diamine-Tethered Bis(thiourea) Organocatalyst for Asymmetric Henry Reaction. Journal of Organic Chemistry. 2017. Dostupné z: https://doi.org/10.1021/acs.joc.7b00079.

BOBÁĽ, Pavel; Jan OTEVŘEL; Z. POBORILOVA; Veronika VAVERKOVÁ; Jozef CSÖLLEI a Petr BABULA. Application of BY-2 cell model in evaluating an effect of newly prepared potential calcium channel blockers. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES. KARACHI: UNIV KARACHI, 2015, roč. 28, č. 4, s. 1281-1293. ISSN 1011-601X.