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Anemia-associated mutations disrupt the CDIN1-Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA-I) disease J - Článek v odborném periodikuSTOJASPAL, Martin; Tomáš BROM; Ivona NEČASOVÁ; Tomáš JANOVIČ; Pavel VEVERKA; Naina VERMA; Lukáš UHRÍK; Lenka HERNYCHOVÁ a Ctirad HOFR. Anemia-associated mutations disrupt the CDIN1-Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA-I) disease. FEBS Journal. SPRINGER VERLAG, 2026. ISSN 1742-464X. Dostupné z: https://doi.org/10.1111/febs.70421.Podrobněji: https://is.muni.cz/publication/2551310/cs
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How does phosphorylation of 14-3-3ζ protein affect its structure and function? a - Konferenční abstraktKOZELEKOVÁ, Aneta; Alexandra NÁPLAVOVÁ; Radek CRHA; Tomáš BROM a Jozef HRITZ. How does phosphorylation of 14-3-3ζ protein affect its structure and function? In CEITEC PhD School conference 2025, Brno. 2025.Podrobněji: https://is.muni.cz/publication/2513602/cs
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Replication and transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy a - Konferenční abstraktBROM, Tomáš; Pavel VEVERKA; Tomáš JANOVIČ; Martin STOJASPAL; Tereza PAŘÍKOVÁ a Ctirad HOFR. Replication and transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy. In XXI Discussions in Structural Molecular Biology and 8th User Meeting of CIISB. 2025.Podrobněji: https://is.muni.cz/publication/2539964/cs
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Transcriptional regulation of Epstein-Barr oncovirus – biophysical implications for Rta-targeted therapy a - Konferenční abstraktBROM, Tomáš; Pavel VEVERKA; Jarmila MLČOUŠKOVÁ; Eva POSPÍŠILOVÁ; Tereza PAŘÍKOVÁ a Ctirad HOFR. Transcriptional regulation of Epstein-Barr oncovirus – biophysical implications for Rta-targeted therapy. In 4th Chromosomal Instability as a Driver of Human Disease Conference. 2025.Podrobněji: https://is.muni.cz/publication/2552017/cs
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Insight into inherited anemia CDA-I: disease-associated mutations disrupt Codanin1-CDIN1 complex a - Konferenční abstraktBROM, Tomáš; Martin STOJASPAL; Tomáš JANOVIČ; Pavel VEVERKA; Eva POSPÍŠILOVÁ a Ctirad HOFR. Insight into inherited anemia CDA-I: disease-associated mutations disrupt Codanin1-CDIN1 complex. In FEBS Practical course - Advanced methods in macromolecular crystallization. 2024.Podrobněji: https://is.muni.cz/publication/2458902/cs
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Rta - Replication and transcription activator of Epstein-Barr virus: functional and structural implications for novel antiviral strategy a - Konferenční abstraktBROM, Tomáš; Tomáš JANOVIČ; Martin STOJASPAL; Pavel VEVERKA a Ctirad HOFR. Rta - Replication and transcription activator of Epstein-Barr virus: functional and structural implications for novel antiviral strategy. In XX Discussions in Structural Molecular Biology and 5th User Meeting of the Czech Infrastructure for Integrative Structural Biology. 2024.Podrobněji: https://is.muni.cz/publication/2458898/cs
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Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST – RE1-silencing transcription factor J - Článek v odborném periodikuVEVERKA, Pavel; Tomáš BROM; Tomáš JANOVIČ; Martin STOJASPAL; Matyáš PINKAS; Jiří NOVÁČEK a Ctirad HOFR. Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST – RE1-silencing transcription factor. Computational and Structural Biotechnology Journal. Elsevier, 2023, roč. 21, Dec, s. 731-741. ISSN 2001-0370. Dostupné z: https://doi.org/10.1016/j.csbj.2022.12.026.Podrobněji: https://is.muni.cz/publication/2247909/cs
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Insight into inherited anemia CDA-I: disease-associated mutations disrupt Codanin1-CDIN1 complex k - Prezentace na konferencíchBROM, Tomáš; Martin STOJASPAL; Tomáš JANOVIČ; Ivona NEČASOVÁ; Pavel VEVERKA a Ctirad HOFR. Insight into inherited anemia CDA-I: disease-associated mutations disrupt Codanin1-CDIN1 complex. In XIX Discussions in Structural Molecular Biology and 6th User Meeting of the Czech Infrastructure for Integrative Structural Biology. 2023.Podrobněji: https://is.muni.cz/publication/2273717/cs
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Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres J - Článek v odborném periodikuSTORCHOVA, Radka; Matouš PALEK; Natálie PALKOVA; Pavel VEVERKA; Tomáš BROM; Ctirad HOFR a Libor MACŮREK. Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. Nucleic Acids Research. Oxford University Press, 2023, roč. 51, č. 3, s. 1154-1172. ISSN 0305-1048. Dostupné z: https://doi.org/10.1093/nar/gkac1269.Podrobněji: https://is.muni.cz/publication/2249590/cs
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Codanin1 and CDIN1 interaction: implications for inherited anemia progression k - Prezentace na konferencíchBROM, Tomáš; Martin STOJASPAL; Tomáš JANOVIČ; Ivona NEČASOVÁ; Pavel VEVERKA a Ctirad HOFR. Codanin1 and CDIN1 interaction: implications for inherited anemia progression. In XXI. setkání biochemiků a molekulárních biologů. 2022. ISBN 978-80-280-0136-0.Podrobněji: https://is.muni.cz/publication/2244137/cs
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Critical interactions of neuronal transcription factor REST with stabilizer TRF2 a - Konferenční abstraktBROM, Tomáš; Tomáš JANOVIČ; Pavel VEVERKA; Martin STOJASPAL a Ctirad HOFR. Critical interactions of neuronal transcription factor REST with stabilizer TRF2. 2022.Podrobněji: https://is.muni.cz/publication/1843617/cs
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Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy a - Konferenční abstraktBROM, Tomáš; Tomáš JANOVIČ; Martin STOJASPAL; Eliška KŮŘILOVÁ; Simona CHLUDILOVÁ a Ctirad HOFR. Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy. In 1st MOSBRI Scientific Conference. 2022. Dostupné z: https://doi.org/.Podrobněji: https://is.muni.cz/publication/2223042/cs
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Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy a - Konferenční abstraktBROM, Tomáš; Tomáš JANOVIČ; Martin STOJASPAL; Eliška KŮŘILOVÁ; Simona CHLUDILOVÁ a Ctirad HOFR. Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy. In Instruct Biennial Structural Biology Conference. 2022.Podrobněji: https://is.muni.cz/publication/1855321/cs
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Phosphomimicking mutations ≠ phosphorylation - a case study of 14-3-3 protein a - Konferenční abstraktKOZELEKOVÁ, Aneta; Alexandra NÁPLAVOVÁ; Tomáš BROM; Zuzana TROŠANOVÁ; Petr LOUŠA a Jozef HRITZ. Phosphomimicking mutations ≠ phosphorylation - a case study of 14-3-3 protein. In XVIII Discussions in Structural Molecular Biology and 5th User Meeting of the Czech Infrastructure for Integrative Structural Biology. 2022.Podrobněji: https://is.muni.cz/publication/1844165/cs
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Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein J - Článek v odborném periodikuKOZELEKOVÁ, Aneta; Alexandra NÁPLAVOVÁ; Tomáš BROM; Norbert GAŠPARIK; Jan ŠIMEK; Josef HOUSER a Jozef HRITZ. Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein. Frontiers in Chemistry. Frontiers Media SA, 2022, roč. 10, March, s. 1-17. ISSN 2296-2646. Dostupné z: https://doi.org/10.3389/fchem.2022.835733.Podrobněji: https://is.muni.cz/publication/1839679/cs
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Quantitation of Human 14-3-3ζ Dimerization and the Effect of Phosphorylation on Dimer-monomer Equilibria J - Článek v odborném periodikuTROŠANOVÁ, Zuzana; Petr LOUŠA; Aneta KOZELEKOVÁ; Tomáš BROM; Norbert GAŠPARIK; Ján TUNGLI; Veronika WEISOVÁ; Erik ŽUPA; Gabriel ŽOLDÁK a Jozef HRITZ. Quantitation of Human 14-3-3ζ Dimerization and the Effect of Phosphorylation on Dimer-monomer Equilibria. Journal of Molecular Biology. Elsevier, 2022, roč. 434, č. 7, s. 1-13. ISSN 0022-2836. Dostupné z: https://doi.org/10.1016/j.jmb.2022.167479.Podrobněji: https://is.muni.cz/publication/1839678/cs
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Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy J - Článek v odborném periodikuNEČASOVÁ, Ivona; Martin STOJASPAL; Edita MOTYČÁKOVÁ; Tomáš BROM; Tomáš JANOVIČ a Ctirad HOFR. Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy. NAR Cancer. Oxford University Press, 2022, roč. 4, č. 1, s. 1-16. ISSN 2632-8674. Dostupné z: https://doi.org/10.1093/narcan/zcac005.Podrobněji: https://is.muni.cz/publication/1843018/cs
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When TRF2 is around, REST is in peace - Structural and functional implications of extratelomeric TRF2 protecting neuronal differentiation regulator REST in glioblastoma a - Konferenční abstraktHOFR, Ctirad; Pavel VEVERKA; Tomáš BROM a Tomáš JANOVIČ. When TRF2 is around, REST is in peace - Structural and functional implications of extratelomeric TRF2 protecting neuronal differentiation regulator REST in glioblastoma. In EMBO Workshop on Telomere function and evolution in health and disease 26 September-01 October 2022 | Tróia, Portugal. 2022.Podrobněji: https://is.muni.cz/publication/2255257/cs
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Biophysical characterisation of phosphorylated 14-3-3ζ protein a - Konferenční abstraktKOZELEKOVÁ, Aneta; Alexandra NÁPLAVOVÁ; Tomáš BROM; Norbert GAŠPARIK; Radek CRHA a Jozef HRITZ. Biophysical characterisation of phosphorylated 14-3-3ζ protein. In XXI. Workshop of biophysical chemists and electrochemists. 2021. ISBN 978-80-210-9943-2.Podrobněji: https://is.muni.cz/publication/1844161/cs
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Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 When TPP1 Is Absent a - Konferenční abstraktJANOVIČ, Tomáš; Tomáš BROM; Martin STOJASPAL; Pavel VEVERKA; Denisa HORÁKOVÁ a Ctirad HOFR. Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 When TPP1 Is Absent. In 26th International Workshop on “Single Molecule Spectroscopy and Super-resolution Microscopy”. 2021.Podrobněji: https://is.muni.cz/publication/1795983/cs
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HOW PHOSPHORYLATION IMPACTS 14-3-3ζ DIMERIZATION a - Konferenční abstraktLOUŠA, Petr; Zuzana TROŠANOVÁ; Aneta KOZELEKOVÁ; Tomáš BROM; Norbert GAŠPARIK; Veronika WEISOVÁ; G. ŽOLDÁK a Jozef HRITZ. HOW PHOSPHORYLATION IMPACTS 14-3-3ζ DIMERIZATION. In XX. Workshop of Biophysical Chemists and Electrochemists. 2020. ISBN 978-80-210-9655-4.Podrobněji: https://is.muni.cz/publication/1710376/cs
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Influence of the geometry of fluorescently labelled DNA constructs on fluorescence anisotropy assay J - Článek v odborném periodikuBROM, Tomáš; Francesco V REDDAVIDE; Stephan HEIDEN; Michael THOMPSON a Yixin ZHANG. Influence of the geometry of fluorescently labelled DNA constructs on fluorescence anisotropy assay. Biochemical and biophysical research communications. Elsevier, 2020, roč. 533, č. 2, s. 230-234. ISSN 0006-291X. Dostupné z: https://doi.org/10.1016/j.bbrc.2020.04.025.Podrobněji: https://is.muni.cz/publication/1675424/cs
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Molecular mechanism of glioblastoma cell differentiation a - Konferenční abstraktBROM, Tomáš; Martin STOJASPAL; Tomáš JANOVIČ; Pavel VEVERKA a Ctirad HOFR. Molecular mechanism of glioblastoma cell differentiation. In FEBS INSTRUCT MOBIEU Practical course: Hydrodynamic and ther- modynamic analysis of biological macromolecules and their interactions. 2020.Podrobněji: https://is.muni.cz/publication/1719336/cs
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Monomer-dimer equilibria of 14-3-3ζ protein. a - Konferenční abstraktBROM, Tomáš; Zuzana TROŠANOVÁ; Petr LOUŠA; Norbert GAŠPARIK; Krishnendu BERA; Gabriel ŽOLDÁK a Jozef HRITZ. Monomer-dimer equilibria of 14-3-3ζ protein. In XVI. Discussions in Structural Molecular Biology. 2019.Podrobněji: https://is.muni.cz/publication/1598936/cs
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Structural study of 14-3-3ζ monomeric mutant. k - Prezentace na konferencíchBROM, Tomáš; Aneta KOZELEKOVÁ; Petr LOUŠA; Norbert GAŠPARIK; Krishnendu BERA; Gabriel ŽOLDÁK a Jozef HRITZ. Structural study of 14-3-3ζ monomeric mutant. In XIXth Workshop of Physical Chemist and Electrochemists. 2019. ISBN 978-80-210-9309-6.Podrobněji: https://is.muni.cz/publication/1598877/cs
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Determination of the dimer-monomer equilibrium of 14-3-3ζ protein. k - Prezentace na konferencíchBROM, Tomáš; Zuzana TROŠANOVÁ; Petr LOUŠA; Veronika WEISOVÁ; Gabriel ŽOLDÁK a Jozef HRITZ. Determination of the dimer-monomer equilibrium of 14-3-3ζ protein. In XVIIth Workshop of Physical Chemist and Electrochemists. 2017. ISBN 978-80-210-8580-0.Podrobněji: https://is.muni.cz/publication/1598916/cs
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Thermodynamic and kinetic study of 14-3-3ζ dimerization a - Konferenční abstraktTROŠANOVÁ, Zuzana; Petr LOUŠA; Tomáš BROM; Veronika WEISOVÁ; Gabriel ŽOLDÁK a Jozef HRITZ. Thermodynamic and kinetic study of 14-3-3ζ dimerization. In XVIIth Workshop of Physical Chemist and Electrochemists. 2017. ISBN 978-80-210-8580-0.Podrobněji: https://is.muni.cz/publication/1598918/cs