aZLPF0622c Pathological Physiology II - practice

Faculty of Medicine
spring 2024
Extent and Intensity
0/2/0. 1 credit(s). Type of Completion: z (credit).
Taught in person.
MUDr. Kamil Ďuriš, Ph.D. (seminar tutor)
MUDr. Michal Jurajda, Ph.D. (seminar tutor)
MUDr. Jan Máchal, Ph.D. (seminar tutor)
prof. RNDr. Michal Masařík, Ph.D. (seminar tutor)
Mgr. Lukáš Pácal, Ph.D. (seminar tutor)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (seminar tutor)
prof. MUDr. Anna Vašků, CSc. (seminar tutor)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Supplier department: Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Prerequisites (in Czech)
aZLPF0521c Pathophysiol. I - practice && aZLBC0422p Biochemistry II - lecture && aZLFY0422p Physiology II - lecture
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The objective of the practical exercises and seminars from pathological physiology is to provide students basic idea about experimental work during pathological conditions (diseases).
Learning outcomes
The student will explain the pathophysiology of selected GIT disorders;
The student demonstrates the principle of load test (oGTT) in an animal model of experimentally induced diabetes (alloxan);
The student shall identify clinically relevant parameters describe nutritional status (calorimetry, BMI, WHR index, the weight, the skin-fold thickness, bioimpedance, DEXA) ;
The student demonstrates onset of obstruction icterus induced by ligation of ductus choledochus. The student understands etiopathogenesis of other types of icterus (hemolytic, hepatic) and diagnostics of them using heme metabolites in urine, blood and stool using mitochondrial/cytoplasmatic membranes liver enzymes;
The student describes etiopathogenesis of venous thrombosis using data from an experimental animal model;
Student discusses cerebrovascular disease, intracranial hypertension with regard to etiology;
The student discusses the connection with the development and progression of shock states with regard to the pathophysiology of anaphylactic shock.
  • Practical exercises:
  • Anaphylactic reaction. Shock states (tutorial)
  • Anaemias, microscopy. (tutorial)
  • Pathophysiology of selected disorders of GIT (tutorial) I
  • Pathophysiology of selected disorders of GIT (tutorial) II
  • Statistical analyses
  • Exp. induced diabetes mellitus – diagnosis by glucose tolerance test
  • Neuropathophysiology (tutorial)
  • Exp. induced haemolytic, hepatotoxic and obstruction jaundice in lab. animal. Use of enzyme (and other) markers in diagnostics of selected pathophysiological states.
  • Exp. induced vein thrombosis in lab. animal
  • Eating disorders (tutorial) + credits
Teaching methods
Practical training.
Assessment methods
Credit. Practical exercises are compulsory (absence can be excused only in case of sick leave). During the term, tutors can continuously test knowledge in written tests or students can be asked to elaborate special papers. Term tuition (blocks) is completed by credit, conditions for awarding credit are: i) participation in the practical exercises, ii) elaboration of protocols from experimental practical exercises, iii) further individually chosen tutor's criteria.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023.
  • Enrolment Statistics (spring 2024, recent)
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