aFAFK1_14 Pharmacology I

Faculty of Pharmacy
Spring 2026

The course is not taught in Spring 2026

Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
PharmDr. Tereza Kauerová, Ph.D. (lecturer)
doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
Guaranteed by
doc. PharmDr. Peter Kollár, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Prerequisites (in Czech)
aFAFC2_14 Human Phys. and Pathophys II. && aFABC1_16 Biochemistry for Pharmacists
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Learning outcomes
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Key topics
  • - Introduction into the pharmacology
  • - Preclinical and clinical drug testing
  • - Pharmacokinetic processes
  • - Pharmacokinetic parameters and their clinical significance
  • - Receptor theory. Types of receptors
  • - Mechanisms of transmembrane transport of drugs, transport of drugs across organ barriers
  • - Routes of drug administration
  • - Basic pharmacodynamic processes (Dose-drug relationship. - Intercellular signaling. Drug-receptor interaction)
  • - General principles of poisoning therapy. Drug addictions (classification, mechanisms of origin, possibilities of therapy)
  • - Factors influencing the effect of a drug
Study resources and literature
    required literature
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    recommended literature
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Approaches, practices, and methods used in teaching
lectures
Method of verifying learning outcomes and course completion requirements
Written final test
Language of instruction
English
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