aVLFA0721c Farmakologie I - cvičení

Lékařská fakulta
podzim 2026
Rozsah
0/3/0. 45. 2 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
doc. MUDr. Regina Demlová, Ph.D. (cvičící)
doc. PharmDr. Jan Juřica, Ph.D. (cvičící)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (přednášející)
Mgr. Petra Amchová, Ph.D. (cvičící)
doc. RNDr. Ladislava Bartošová, Ph.D. (cvičící)
PharmDr. Adéla Bártová (cvičící)
MVDr. Eva Dražanová, Ph.D. (cvičící)
Carlos Daniel Ferreira Fonseca, MSc. (cvičící)
PharmDr. Petr John (cvičící)
Mgr. Jana Kubátová, Ph.D. (cvičící)
MUDr. Alena Máchalová, Ph.D. (cvičící)
MUDr. Jana Nováková, Ph.D. (cvičící)
MUDr. Jana Pistovčáková, Ph.D. (cvičící)
doc. PharmDr. Jana Rudá, Ph.D. (cvičící)
PharmDr. Jitka Rychlíčková, Ph.D. (cvičící)
Mgr. Barbora Říhová, Ph.D. (cvičící)
PharmDr. Lenka Součková, Ph.D. (cvičící)
doc. PharmDr. Ondřej Zendulka, Ph.D. (cvičící)
Garance
doc. MUDr. Regina Demlová, Ph.D.
Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Dodavatelské pracoviště: Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLFA0721c/30: Út 22. 9. 16:00–18:30 E24/N02317, Út 29. 9. 16:00–18:30 E24/N02317, Út 6. 10. 16:00–18:30 E24/N02317, Út 13. 10. 16:00–18:30 E24/N02317, Út 20. 10. 16:00–18:30 E24/N02317, Út 27. 10. 16:00–18:30 E24/N02317, Út 3. 11. 16:00–18:30 E24/N02317, Út 10. 11. 16:00–18:30 E24/N02317, Út 24. 11. 16:00–18:30 E24/N02317, Út 1. 12. 16:00–18:30 E24/N02317, Út 8. 12. 16:00–18:30 E24/N02317, Út 15. 12. 16:00–18:30 E24/N02317, Út 5. 1. 16:00–18:30 E24/N02317, Út 12. 1. 16:00–18:30 E24/N02317
aVLFA0721c/31: Po 21. 9. 16:00–18:30 E24/N02318, Po 5. 10. 16:00–18:30 E24/N02318, Po 12. 10. 16:00–18:30 E24/N02318, Po 19. 10. 16:00–18:30 E24/N02318, Po 26. 10. 16:00–18:30 E24/N02318, Po 2. 11. 16:00–18:30 E24/N02318, Po 9. 11. 16:00–18:30 E24/N02318, Po 16. 11. 16:00–18:30 E24/N02318, Po 23. 11. 16:00–18:30 E24/N02318, Po 30. 11. 16:00–18:30 E24/N02318, Po 7. 12. 16:00–18:30 E24/N02318, Po 14. 12. 16:00–18:30 E24/N02318, Po 4. 1. 16:00–18:30 E24/N02318, Po 11. 1. 16:00–18:30 E24/N02318
aVLFA0721c/32: Út 22. 9. 16:00–18:30 E24/N02318, Út 29. 9. 16:00–18:30 E24/N02318, Út 6. 10. 16:00–18:30 E24/N02318, Út 13. 10. 16:00–18:30 E24/N02318, Út 20. 10. 16:00–18:30 E24/N02318, Út 27. 10. 16:00–18:30 E24/N02318, Út 3. 11. 16:00–18:30 E24/N02318, Út 10. 11. 16:00–18:30 E24/N02318, Út 24. 11. 16:00–18:30 E24/N02318, Út 1. 12. 16:00–18:30 E24/N02318, Út 8. 12. 16:00–18:30 E24/N02318, Út 15. 12. 16:00–18:30 E24/N02318, Út 5. 1. 16:00–18:30 E24/N02318, Út 12. 1. 16:00–18:30 E24/N02318, J. Pistovčáková
aVLFA0721c/33: Po 21. 9. 13:15–15:45 E24/N02317, Po 5. 10. 13:15–15:45 E24/N02317, Po 12. 10. 13:15–15:45 E24/N02317, Po 19. 10. 13:15–15:45 E24/N02317, Po 26. 10. 13:15–15:45 E24/N02317, Po 2. 11. 13:15–15:45 E24/N02317, Po 9. 11. 13:15–15:45 E24/N02317, Po 16. 11. 13:15–15:45 E24/N02317, Po 23. 11. 13:15–15:45 E24/N02317, Po 30. 11. 13:15–15:45 E24/N02317, Po 7. 12. 13:15–15:45 E24/N02317, Po 14. 12. 13:15–15:45 E24/N02317, Po 4. 1. 13:15–15:45 E24/N02317, Po 11. 1. 13:15–15:45 E24/N02317, O. Zendulka
aVLFA0721c/34: Po 21. 9. 16:00–18:30 E24/N02317, Po 5. 10. 16:00–18:30 E24/N02317, Po 12. 10. 16:00–18:30 E24/N02317, Po 19. 10. 16:00–18:30 E24/N02317, Po 26. 10. 16:00–18:30 E24/N02317, Po 2. 11. 16:00–18:30 E24/N02317, Po 9. 11. 16:00–18:30 E24/N02317, Po 16. 11. 16:00–18:30 E24/N02317, Po 23. 11. 16:00–18:30 E24/N02317, Po 30. 11. 16:00–18:30 E24/N02317, Po 7. 12. 16:00–18:30 E24/N02317, Po 14. 12. 16:00–18:30 E24/N02317, Po 4. 1. 16:00–18:30 E24/N02317, Po 11. 1. 16:00–18:30 E24/N02317
Předpoklady
aVLPF0622p Pathophysiology II - lecture && aVLPA0622c Patologie II - cvičení
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Anotace

This course aims to help understand pharmacological terms and legislation relating to medicines; the fundamentals of prescribing medicinal products; and the differences among individual dosage forms, methods of administration, and their impact on the effects of medicines, and to gain an overview of basic pharmacokinetic processes and parameters, possible mechanisms of drug action, types of adverse effects and factors that influence the effect of drugs.


In the introduction to Special Pharmacology, students will become familiar with the fundamentals of pharmacology, profiles of selected drug groups, including their specific indications, mechanisms of action, pharmacokinetic properties, and methods of administration. drugs, possible adverse effects, drug interactions and contraindications.

Výstupy z učení
After completing the course, students will understand the legislation governing the use of medicines, distinguish between different dosage forms and methods of administration, understand pharmacokinetic processes and be able to calculate selected pharmacokinetic parameters, be familiar with the pharmacodynamics of drugs and types of adverse effects, and be able to describe factors influencing the effect of drugs, including clinically significant examples. The student has an overview of selected drug groups used in clinical practice and is familiar with their basic pharmacological profiles. The student can prescribe Ready-made medicinal products using available resources.
Klíčová témata

  • aVLFA0721c - Pharmacology I - practical lessons

    General medicine

    Autumn semester

  • Topic 1: INFORMATION ON DRUGS
  • Organisation of practical courses and lectures, our system of evaluation. Repetition of basic pharmacologic terminology. Sub-branches of pharmacology. Sources of information concerning drugs and recommended textbooks. Work with relevant databases (Brevíř, SÚKL, EMA, AISLP), and ATC classification.
  • Topic 2: ROUTES OF DRUG ADMINISTRATION, DRUG DOSAGE FORMS
  • Brief characteristics of the individual drug dosage forms. Clinical significance of the way of drug administration. Overview of the drug dosage forms.
  • Topic 3: PRESCRIPTION OF MEDICINAL PRODUCTS
  • General rules of drug prescription. Prescription of the ready-made preparations.
  • Topic 4: PHARMACOKINETICS I
  • Pharmacokinetic processes, parameters and calculations.
  • Topic 5: PHARMACOKINETICS II
  • Pharmacokinetic case reports, simulation of plasma concentrations course, dosage optimization and use of software tools, factors affecting course and value of drug´s plasma concentrations.
  • Topic 6: PHARMACODYNAMICS
  • MULTIPLE-CHOICE TEST I (Topics 1-5).
  • Mechanisms of drug effects - classification, examples. Dose-response curves.
  • Topic 7: FACTORS AFFECTING DRUG EFFECTS
  • Pharmacotherapy in childhood, in pregnancy, in breastfeeding women, in the elderly. Beers list, STOPP-START, FORTA, PLLR.
  • Topic 8: PHARMACOVIGILANCE, ADVERSE DRUG REACTIONS
  • PRESCRIPTION TEST
  • Classification and characteristics of adverse drug effects. Pharmacovigilance in clinical practice, sources of information on drug safety.
  • Topic 9: PHARMACOLOGY OF SYMPATHETIC NERVOUS SYSTEM
  • Receptors of the sympathetic nervous system (alpha, beta) and their subtypes and organ distribution. Classification and basic pharmacological characteristics of drugs influencing the sympathetic nervous system (pharmacodynamics - both direct and indirect mechanisms of drug action, systems of second messengers).
  • Topic 10: PHARMACOLOGY OF PARASYMPATHETIC NERVOUS SYSTEM, SPASMOLYTIC DRUGS, MUSCLE RELAXANTS
  • Drugs affecting the parasympathetic nervous system - classification, basic pharmacological characteristics. Spasmolytic drugs.
  • Topic 11: GLUCOCORTICOIDS, DRUGS USED FOR TREATMENT OF HYPO/HYPERTHYROIDISM
  • MULTIPLE-CHOICE TEST II (Topics 6-10).
  • Repetition of basic pharmacological characteristics of glucocorticoids and drugs used for treatment of thyroid gland diseases.
  • Topic 12: ANALGESICS, PHARMACOTHERAPY OF GOUT
  • Basic pharmacological characteristics of opioid and non-opioid analgesic drugs, antirheumatoid drugs and drugs used in gout.
  • Topic 13: H1-ANTIHISTAMINES, THERAPY OF DISEASES WITH BRONCHIAL OBSTRUCTION, THERAPY OF COUGH
  • H1-antihistamines, drugs used for therapy of diseases with bronchial obstruction, inhalation drug dosage forms. Drugs used for the therapy of cough.
  • Topic 14: PHARMACOTHERAPY OF DIABETES MELLITUS
  • Anti-diabetic drugs - basic pharmacological characteristics. Drugs used in the therapy of specific and acute conditions in diabetology. Combinations of insulins, insulin regimens.
  • Topic 15: SEX HORMONES
  • MULTIPLE-CHOICE TEST 3 (Topics 11-14).
  • Endocrine therapy, hormone replacement therapy, hormonal contraceptive drugs. Uterotonics and tocolytics. Hormones of HPA axis.
Studijní zdroje a literatura
    povinná literatura
  • Practicals in Pharmacology, 2009, Náhradní obsah: http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON a James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    neurčeno
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
  • Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmacology. Edited by Michelle Alexia Clark. 5th ed. Baltimore: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012, xii, 612. ISBN 9781451113143. info
  • LÜLLMANN, Heinz; Lutz HEIN a Klaus MOHR. Color atlas of pharmacology. Translated by Detlef Bierger, Illustrated by Jürgen Wirth. 4th ed. Stuttgart: Thieme, 2011, x, 393. ISBN 9783137817048. info
Záložky
https://is.muni.cz/ln/tag/LF:aVLFA0721c!
Přístupy, postupy a metody používané ve výuce

Participation in pharmacology seminars requires students to prepare for class by studying the study materials provided in advance in the MUNI IS. The exercises themselves further deepen theoretical knowledge by connecting individual topics, applying them to specific examples from clinical practice, and consolidating long-term knowledge through active learning. 


The teacher encourages active discussion, guides students through the solution of individual cases with targeted questions, and responds to the needs of the seminar group. At the same time, they adhere to the preset schedule for each teaching unit to maintain uniform learning outcomes.

Způsob ověření výstupů z učení a požadavky na ukončení

Participation in seminars is mandatory. Students are allowed two unexcused absences. To obtain credit, students must successfully pass the following tests:


Prescription test - students are tasked with prescribing 2 Ready-made products using a drug database; the assignment includes indications and other information about the patient necessary for the correct selection of the active substance and duration of therapy (drug form/route of administration, quantity of the product)


3x Multiple-choice test - each test contains 15 questions, the number of correct answers is specified in the assignment, the pass mark is 6 points and a total of 20 points from 3 tests. It is possible to retake one test, no more than once per semester.


To obtain credit, students must meet the attendance requirement and pass all tests with a minimum total of 20 points.

Náhradní absolvování
For an internship, students can participate in online exercises. Tests are taken in person after returning from the internship. This option must be discussed with the course contact person before the start of the semester.
Vyučovací jazyk
Angličtina
Navazující předměty
Odkaz a informace vyučujících
https://is.muni.cz/auth/el/1411/podzim2026/aVLFA0721c/
Consultation hours and test substitutions/corrections are always in the week following the test in the FarmÚ classroom after logging in via the IS Topic Lists.
Students may use two unexcused absences per semester.

Studijní opora
https://is.muni.cz/auth/el/1411/podzim2026/aVLFA0721c/
Další komentáře
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