aVLFA0822c Farmakologie II - cvičení

Lékařská fakulta
jaro 2027
Rozsah
0/3/0. 45. 2 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
doc. MUDr. Regina Demlová, Ph.D. (náhr. zkoušející)
doc. PharmDr. Jan Juřica, Ph.D. (cvičící)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (přednášející)
Mgr. Petra Amchová, Ph.D. (cvičící)
Carlos Daniel Ferreira Fonseca, MSc. (cvičící)
PharmDr. Katarína Kostolanská, Ph.D. (cvičící)
MUDr. Jana Pistovčáková, Ph.D. (cvičící)
PharmDr. Jitka Rychlíčková, Ph.D. (cvičící)
PharmDr. Lenka Součková, Ph.D. (cvičící)
doc. PharmDr. Ondřej Zendulka, Ph.D. (cvičící)
doc. RNDr. Ladislava Bartošová, Ph.D. (pomocník)
Mgr. Jana Kubátová, Ph.D. (pomocník)
MUDr. Jana Nováková, Ph.D. (pomocník)
doc. PharmDr. Jana Rudá, Ph.D. (pomocník)
Mgr. Barbora Říhová, Ph.D. (pomocník)
PharmDr. Petr John (cvičící)
Garance
doc. MUDr. Regina Demlová, Ph.D.
Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Dodavatelské pracoviště: Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Předpoklady
aVLFA0721p Farmakologie I - přednáška && aVLPF0622p Pathophysiology II - lecture
Pharmacology II builds on the previous semester's Pharmacology I.
Omezení zápisu do předmětu
Předmět je nabízen i studentům mimo mateřské obory.
Mateřské obory/plány
Anotace
The aim of the course is to introduce students to the basic pharmacological profiles of selected groups of drugs (mechanism of action, pharmacokinetic properties, methods of application,  indications, adverse effects, drug interactions, and contraindications) and to apply theoretical knowledge at the level of selecting the appropriate drug to ensure safe and effective pharmacotherapy.
Výstupy z učení
After completing the course, students will have an overview of the drug groups used in clinical practice, be familiar with the basic pharmacological profiles of individual drugs, and be able to select and prescribe a medicinal product for a patient based on a known diagnosis, using the available information and a drug database. The choice of drug is based on consideration of all factors affecting its safety and efficacy.
Klíčová témata

  • aVLFA0822c - Pharmacology II practicals

    General medicine

    Spring semester 

  • 1. ANTIPSYCHOTICS, ANTIPARKINSONICS, PROKINETICS
  • Content of the lesson: Classification of psychotropic medicines, pharmacology of dopaminergic system with the focus on antipsychotics, antiparkinsonics and prokinetics.
  • 2. ANTIDEPRESSANTS
  • Content of the lesson: Pharmacological review of antidepressants, cognitive enhancers and psychostimulants.
  • 3. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
  • Content of the lesson: GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, adverse effects. Rules in the therapy of anxiety, sleeping disorders and seizures with respect to specific subpopulations. Psychopharmacological case reports. Drug dependence and its treatment.
  • 4. GENERAL AND LOCAL ANAESTHETICS
  • Content of the lesson: Basic pharmacological features of general and local anaesthetics. Review of drugs used in premedication.
  • 5. VASODILATORS AND DRUGS WITH EFFECT ON VESSELS
  • MCQ TEST I 
  • Content of the lesson: Lipid-lowering drugs, nitrates, donors of NO groups, calcium channel blockers and other groups of direct vasodilators. Risk factors of cardiovascular diseases.
  • 6. DRUGS INFLUENCING RAAS. DIURETICS.
  • Content of the lesson: ACE inhibitors, sartans, inhibitors of renin, diuretics. Antagonists of mineralocorticoid receptors. Antihypertensives of the 1st and 2nd choice, combined therapy.
  • 7. DRUGS DIRECTLY INFLUENCING MYOCARDIUM
  • Content of the lesson: Beta-blockers and bradins, drugs with positive inotropic effects. Calcium channel blockers - non-DHP, antiarrhythmics. Therapy of heart failure.
  • 8. DRUGS INFLUENCING HAEMOSTASIS
  • Content of the lesson: Classification of drugs interfering with the process of haemostasis, pharmacological review of anticoagulants, antiplatelet drugs, fibrinolytics and antianaemics.
  • 9. THERAPY OF INTOXICATIONS
  • MCQ TEST II 
  • Principles of therapy of intoxications: toxidroms, specific and non-specific therapy of intoxications, antidotes. Work with websites of toxicological centres.
  • 10. ANTI-INFECTIVES I – ANTIBACTERIAL SUBSTANCES
  • Content of the lesson: Pharmacological review of antibiotics, PK/PD parameters, selection of ATB, case reports, bacterial resistance.
  • 11. ANTI-INFECTIVES II – ANTIFUNGAL AND ANTIVIRAL DRUGS, DERMATOLOGICS
  • Content of the lesson: Therapy of respiratory infections, UTI, intensive care. Overview of antimycotics and antivirotics, Dermatologics – classification and pharmacological review, local anti-infectives, revision of drug prescription.
  • 12. PHARMACOLOGY OF GIT
  • PRESCRIPTION TEST
  • Content of the lesson: Pharmacological review of drugs used in GIT disorders.
  • 13. CYTOSTATICS AND TARGETED THERAPY IN ONCOLOGY
  • Content of the lesson: Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
  • 14. DRUG INTERACTIONS
  • MCQ TEST III
  • Content of the lesson: Case reports focused on drug interactions.
  • 15. PHYTOPHARMACOLOGY
  • Content of the lesson: Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-treatment of selected diseases. Credits.
Studijní zdroje a literatura
    povinná literatura
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN a H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
  • LANDA, Leoš; Jan JUŘICA; Kristýna NOSKOVÁ a Ondřej ZENDULKA. Selected chapters from general pharmacology for students of general medicine and dentistry at MF MU. Brno, 2020. info
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON a James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    doporučená literatura
  • Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • Library of case reports: https://is.muni.cz/auth/do/med/el/case_reports/index_en.html
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
Přístupy, postupy a metody používané ve výuce
Participation in pharmacology exercises requires students to prepare for class by studying the study materials provided in advance in the MUNI IS. The exercises themselves further deepen theoretical knowledge by interconnecting individual topics, applying theoretical knowledge to specific examples from clinical practice, and reinforcing long-term knowledge through active learning. The instructor encourages active discussion, guides students through the resolution of individual cases with targeted questions, and responds to the needs of the seminar group being taught. At the same time, however, the instructor adheres to the pre-set schedule for each teaching unit so that uniform learning outcomes are maintained.
Způsob ověření výstupů z učení a požadavky na ukončení

Participation in exercises is mandatory. Students are allowed two unexcused absences. To obtain credit, students must successfully pass the following tests:

Prescription test - students are tasked with prescribing 2 HVLP using a drug database. The assignment includes indications and other patient information necessary for the correct selection of the drug and duration of therapy (drug form/route of administration, quantity of the product).

3x Multiple-choice test - each test contains 15 questions, the number of correct answers is specified in the assignment for each question, the pass mark is 6 points, and a total of 20 points from 3 tests. It is possible to retake one test, but only once per semester.

To obtain credit, students must meet the attendance requirement and pass all tests with a minimum total of 20 points.

Náhradní absolvování
During an internship, it is possible to access the seminars online. Tests are written in person after returning from the internship. This option should be discussed with the course contact person before the start of the semester.
Vyučovací jazyk
Angličtina
Odkaz a informace vyučujících
https://is.muni.cz/auth/el/1411/jaro2027/aVLFA0822c/
Consultation hours and test substitutions/corrections are always in the week following the test in the Dpt. of Pharmacology classroom after logging in via the IS Topic Lists.
Studijní opora
https://is.muni.cz/auth/el/1411/jaro2027/aVLFA0822c/
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