aVLFA0822c Farmakologie II - cvičení

Lékařská fakulta
jaro 2023
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučováno prezenčně.
Vyučující
doc. MUDr. Regina Demlová, Ph.D. (náhr. zkoušející)
doc. PharmDr. Jan Juřica, Ph.D. (cvičící)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (přednášející)
Mgr. Petra Amchová, Ph.D. (cvičící)
Mgr. Mária Hricková (cvičící)
PharmDr. Katarína Kostolanská (cvičící)
MUDr. Jana Pistovčáková, Ph.D. (cvičící)
PharmDr. Jitka Rychlíčková, Ph.D. (cvičící)
PharmDr. Lenka Součková, Ph.D. (cvičící)
doc. PharmDr. Ondřej Zendulka, Ph.D. (cvičící)
doc. RNDr. Ladislava Bartošová, Ph.D. (pomocník)
Renata Bláblová (pomocník)
PharmDr. Tomáš Hammer (pomocník)
Mgr. Jana Kubátová, Ph.D. (pomocník)
Mgr. Kristýna Nosková, Ph.D. (pomocník)
MUDr. Jana Nováková, Ph.D. (pomocník)
doc. PharmDr. Jana Rudá, Ph.D. (pomocník)
Mgr. Barbora Říhová, Ph.D. (pomocník)
Květoslava Sedlářová (pomocník)
Mgr. Marta Vyoralová (pomocník)
Garance
doc. MUDr. Regina Demlová, Ph.D.
Farmakologický ústav - Teoretická pracoviště - Lékařská fakulta
Kontaktní osoba: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Dodavatelské pracoviště: Farmakologický ústav - Teoretická pracoviště - Lékařská fakulta
Předpoklady
aVLFA0721p Farmakologie I - přednáška && aVLPF0622p Pathophysiology II - lecture
Omezení zápisu do předmětu
Předmět je nabízen i studentům mimo mateřské obory.
Mateřské obory/plány
Cíle předmětu
The aim of the course is to acquiant the students with drugs from selected pharmacotherapeutic groups and to learn them how to use the drugs rationally with respect to their mode of action, indications and contraindications.
Výstupy z učení
At the end of the course student should be able choose and prescribe suitable drug for the patient with known indicication. The selection will be made with respect to all factors influencing drug safety and efficacy.
Osnova
  • aVLFA0822c - Pharmacology II practicals

    General medicine

    Spring semester 2022

  • (21.2. - 25.2. 2022)
  • 1. DRUGS USED IN DISEASES WITH CHRONIC PULMONARY OBSTRUCTION, H 1 -ANTIHISTAMINES, COUGH MEDICINES
  • Content of the lesson: Review of drugs used in the therapy of diseases with chronic pulmonary obstruction, inhalational pharmaceutical forms. Generations of H1 antihistamines and their indications. Cough medicines – classification, modes of action, use in specific subpopulations.
  • (28.2. – 4.3. 2022)
  • 2. ANTIPSYCHOTICS, ANTIPARKINSONICS, PROKINETICS
  • Content of the lesson: Classification of psychotropic medicines, pharmacology of dopaminergic system with the focus on antipsychotics, antiparkinsonics and prokinetics.
  • (7.3. - 11.3. 2022)
  • 3. ANTIDEPRESSANTS
  • Content of the lesson: Pharmacological review of antidepressants, cognitive enhancers and psychostimulants.
  • (14.3. - 18.3. 2022)
  • 4. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
  • Content of the lesson: GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, adverse effects. Rules in the therapy of anxiety, sleeping disorders and seizures with respect to specific subpopulations. Psychopharmacological case reports. Drug dependence and its treatment.
  • (21.3. - 25.3. 2022)
  • 5. VASODILATORS AND DRUGS WITH EFFECT ON VESSELS
  • MCQ TEST No. 1
  • Content of the lesson: Lipid-lowering drugs, nitrates, donors of NO groups, calcium channel blockers and other groups of direct vasodilators. Risk factors of cardiovascular diseases.
  • (28.3. - 1.4. 2022)
  • 6. DRUGS INFLUENCING RAAS. DIURETICS.
  • Content of the lesson: ACE inhibitors, sartans, inhibitors of renin, diuretics. Antagonists of mineralocorticoid receptors. Antihypertensives and their use.
  • (4.4. - 8.4. 2022)
  • 7. DRUGS DIRECTLY INFLUENCING MYOCARDIUM
  • Content of the lesson: Beta-blockers and bradins, drugs with positive inotropic effects. Calcium channel blockers - non-DHP, antiarrhythmics. Therapy of heart failure.
  • (11.4. - 15.4. 2022)
  • 8. DRUGS INFLUENCING HAEMOSTASIS
  • Content of the lesson: Classification of drugs interfering with the process of haemostasis, pharmacological review of anticoagulants, antiplatelet drugs, fibrinolytics and antianaemics.
  • (18.4. - 22.4. 2022)
  • 9. ANTI-INFECTIVES I – ANTIBACTERIAL SUBSTANCES
  • MCQ TEST No. 2
  • Content of the lesson: Pharmacological review of antibiotics, PK/PD parameters, selection of ATB, case reports, bacterial resistance.
  • (25.4. - 29.4. 2022)
  • 10. ANTI-INFECTIVES II – ANTIFUNGAL AND ANTIVIRAL DRUGS, DERMATOLOGICS
  • Content of the lesson: Therapy of respiratory infections, UTI, intensive care. Overview of antimycotics and antivirotics, Dermatologics – classification and pharmacological review, local anti-infectives, revision of drug prescription.
  • (2.5. - 6.5. 2022)
  • 11. DRUGS OF GIT
  • PRESCRIPTION TEST
  • Content of the lesson: Pharmacological review of drugs used in GIT disorders.
  • (9.5. - 13.5. 2022)
  • 12. CYTOSTATICS AND TARGETED THERAPY IN ONCOLOGY
  • Content of the lesson: Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
  • (16.5. - 20.5. 2022)
  • 13. THERAPY OF INTOXICATIONS
  • Content of the lesson: Principles of therapy of intoxications. Case reports focused on intoxications.
  • (23.5. - 27.5. 2022)
  • 14. DRUG INTERACTIONS
  • MCQ TEST No. 3
  • Content of the lesson: Case reports focused on drug interactions.
  • (30.5. - 3.6. 2022)
  • 15. PHYTOPHARMACOLOGY
  • Content of the lesson: Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-treatment of selected diseases. Credits.
Literatura
    povinná literatura
  • RANG, H. P., James RITTER, R. J. FLOWER a Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016. xv, 760. ISBN 9780702053627. info
    doporučená literatura
  • Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015. xi, 664. ISBN 9781451191776. info
    neurčeno
  • Library of case reports: https://is.muni.cz/auth/do/med/el/case_reports/index_en.html
Výukové metody
Drug classes from the Syllabus are actively reviewed by students and supported by the teacher. Possible ambiguities are discussed and learned knowledge is practiced in case reports from real clinical practice. The training of drug prescription with the use of drug compendia and the computer databases.
Metody hodnocení
The participation in practicals is obligatory and registered. Students can miss two classes without excuse. To get credits a students have to pass 4 written tests:

Prescription test
a) 2 RMP, the main indication or pharmacotherapeutic group is stated together with a basic data of the patient significant for correct drug selection
Multiple-choice tests
15 questions, number of correct answers indicated, minimal score to pass 6
one of the tests can be repeated once

The credits will be given to students who: passed the prescription test and scored at least 6 points from each of multiple-choice tests and their total score from these tests is higher than 20.
Vyučovací jazyk
Angličtina
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