Masarykova univerzita

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Filtrování publikací

    2023

    1. BUCEK, Ondřej, Markéta NEZVEDOVÁ a Zdeněk SPÁČIL. Application of the mass spectrometry to identify protein markers of Alzheimer's disease. In Czech Mass Spectrometry Conference 2023, 11th Conference of CSMS (Czech Society for Mass Spectrometry). 2023.
    2. VÁŇOVÁ, Tereza, Jiří SEDMÍK, Jan RAŠKA, Kateřina AMRUZ ČERNÁ, Petr TAUŠ, Veronika POSPÍŠILOVÁ, Markéta NEZVEDOVÁ, Veronika FEDOROVÁ, Soňa KADÁKOVÁ, Hana KLÍMOVÁ, Michaela CAPANDOVÁ, Petra ORVISKÁ, Petr FOJTÍK, Simona BÁRTOVÁ, Karla PLEVOVÁ, Zdeněk SPÁČIL, Hana HŘÍBKOVÁ a Dáša BOHAČIAKOVÁ. Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development. CELL REPORTS. CAMBRIDGE: CELL PRESS, 2023, roč. 42, č. 11, s. 1-27. ISSN 2211-1247. doi:10.1016/j.celrep.2023.113310.
    3. NEMERGUT, Michal, Sérgio Manuel MARQUES, Lukáš UHRÍK, Tereza VÁŇOVÁ, Markéta NEZVEDOVÁ, Darshak Chandulal GADARA, Durga JHA, Jan TULIS, Veronika NOVÁKOVÁ, Joan PLANAS IGLESIAS, Antonín KUNKA, Anthony Thomas P LEGRAND, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Jiří SEDMÍK, Jan RAŠKA, Zbyněk PROKOP, Jiří DAMBORSKÝ, Dáša BOHAČIAKOVÁ, Zdeněk SPÁČIL, Lenka HERNYCHOVÁ, David BEDNÁŘ a Martin MAREK. Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate. Molecular Neurodegeneration. England: BMC, 2023, roč. 18, č. 1, s. 1-25. ISSN 1750-1326. doi:10.1186/s13024-023-00620-9.
    4. KUBÍČKOVÁ, Barbara, Šárka MARTINKOVÁ, Dáša BOHAČIAKOVÁ, Markéta NEZVEDOVÁ, Runze LIU, Ondřej BRÓZMAN, Zdeněk SPÁČIL a Klára HILSCHEROVÁ. Effects of all-trans and 9-cis retinoic acid on differentiating human neural stem cells in vitro. Toxicology. Clare: ELSEVIER IRELAND LTD, 2023, roč. 487, March 2023, s. 1-15. ISSN 0300-483X. doi:10.1016/j.tox.2023.153461.
    5. ČARNA, Maria, Isaac G. ONYANGO, Stanislav KATINA, Dušan HOLUB, Jan Sebastian NOVOTNY, Markéta NEZVEDOVÁ, Durga JHA, Zuzana NEDELSKA, Valentina LACOVICH, Thijs Vande VYVERE, Ruben HOUBRECHTS, Krystine GARCIA-MANSFIELD, Ritin SHARMA, Victoria DAVID-DIRGO, Martin VYHNALEK, Kateřina TEXLOVA, Hernan CHAVES, Nadine BAKKAR, Lucia PERTIERRA, Mojmír VINKLER, Hana MARKOVA, Jan LACZO, Kateřina SHEARDOVÁ, Marcela HORTOVA-KOHOUTKOVA, Jan FRIČ, Giancarlo FORTE, Petr KAŇOVSKY, Silvie BELAŠKOVA, Jiří DAMBORSKÝ, Jakub HORT, Nicholas T. SEYFRIED, Robert BOWSER, Gustavo SEVLEVER, Robert A. RISSMAN, Richard A. SMITH, Marian HAJDUCH, Patrick PIRROTTE, Zdeněk SPÁČIL, Eric B. DAMMER, Clara LIMBÄCK-STOKIN a Gorazd B. STOKIN. Pathogenesis of Alzheimer´s disease: Involvement of the choroid plexus. Alzheimer´s & Dementia. Wiley, 2023, roč. 19, č. 8, s. 3537-3554. ISSN 1552-5260. doi:10.1002/alz.12970.
    6. NEGI, Chander Kant, Darshak Chandulal GADARA, Jiří KOHOUTEK, Lola Murielle BAJARD ÉP.ESNER, Zdeněk SPÁČIL a Luděk BLÁHA. Replacement Flame-Retardant 2-Ethylhexyldiphenyl Phosphate (EHDPP) Disrupts Hepatic Lipidome: Evidence from Human 3D Hepatospheroid Cell Culture. ENVIRONMENTAL SCIENCE & TECHNOLOGY. WASHINGTON: AMER CHEMICAL SOC, 2023, roč. 57, č. 5, s. 2006-2018. ISSN 0013-936X. doi:10.1021/acs.est.2c03998.
    7. NEZVEDOVÁ, Markéta, Durga JHA, Tereza VÁŇOVÁ, Darshak Chandulal GADARA, Hana KLÍMOVÁ, Jan RAŠKA, Lukáš OPÁLKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits. Analytical Chemistry. American Chemical Society, 2023, roč. 95, č. 6, s. 3160-3167. ISSN 0003-2700. doi:10.1021/acs.analchem.2c00981.

    2022

    1. COSTANTINI, C., E. NUNZI, A. SPOLZINO, F. MERLI, L. FACCHINI, A. SPADEA, L. MELILLO, K. CODELUPPI, F. MARCHESI, G. MARCHESINI, D. VALENTE, G. DRAGONETTI, G. NADALI, Lukas ENGLMAIER, Kateřina COUFALÍKOVÁ, Zdeněk SPÁČIL, M.M. BELLET, M. PARIANO, G. RENGA, C. STINCARDINI, F. D'ONOFRIO, S. BOZZA, L. PAGANO, F. AVERSA a L. ROMANI. A High-Risk Profile for Invasive Fungal Infections Is Associated with Altered Nasal Microbiota and Niche Determinants. INFECTION AND IMMUNITY. WASHINGTON: American Society for Microbiology, 2022, roč. 90, č. 4, s. 1-14. ISSN 0019-9567. doi:10.1128/iai.00048-22.
    2. SEDMÍK, Jiří, Tereza VÁŇOVÁ, Jan RAŠKA, Kateřina AMRUZ ČERNÁ, Veronika POSPÍŠILOVÁ, Veronika FEDOROVÁ, Petr FOJTÍK, Simona VOCHYÁNOVÁ, Hana KLÍMOVÁ, Klára PLEŠINGROVÁ, Petr TAUŠ, Karla PLEVOVÁ, Markéta NEZVEDOVÁ, Zdeněk SPÁČIL, Michaela CAPANDOVÁ, Petra ORVISKÁ, Z. BENEŠOVÁ, P. ABAFY, L. VALIHRACH a Jana HOUSEROVÁ. Cerebral organoids in disease modeling. In PhD retreat 2022, Telč. 2022.
    3. SPÁČIL, Zdeněk, Durga JHA, Markéta NEZVEDOVÁ a Darshak Chandulal GADARA. CEREBRAL ORGANOIDS MODEL SYSTEM FOR NEUROLOGICAL DISEASES. In The International Mass Spectrometry Conference 2022, Maastricht, Netherland. 2022.
    4. NEZVEDOVÁ, Markéta, Tereza VÁŇOVÁ, Jan RAŠKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Single cerebral organoid mass spectrometry analysis: Towards neurodegenerative diseases. In The International Mass Spectrometry Conference 2022, Maastricht, Netherland. 2022.
    5. SCHNEIDER, Marcel, Marina FELIPE GROSSI, Darshak Chandulal GADARA, Zdeněk SPÁČIL, Pavel BABICA a Luděk BLÁHA. Treatment of cylindrospermopsin by hydroxyl and sulfate radicals: Does degradation equal detoxification. Journal of Hazardous Materials. Amsterdam: Elsevier Science BV., 2022, roč. 424, February 2022, s. 1-15. ISSN 0304-3894. doi:10.1016/j.jhazmat.2021.127447.

    2021

    1. BENEŠOVÁ, Eliška, Veronika VIDOVÁ a Zdeněk SPÁČIL. A comparative study of synthetic winged peptides for absolute protein quantification. Nature Scientific Reports. London: NATURE RESEARCH, 2021, roč. 11, č. 1, s. 1-10. ISSN 2045-2322. doi:10.1038/s41598-021-90087-9.
    2. GADARA, Darshak Chandulal, Markéta NEZVEDOVÁ, Durga JHA, Eliška BENEŠOVÁ a Zdeněk SPÁČIL. Advances in mass spectrometry-based metabolomics and quantitative proteomics. In Czech Mass Spectrometry Conference 2021, 9th Conference of CSMS (Czech Society for Mass Spectrometry), Prague, Czech Republic. 2021.
    3. ZELANTE, Teresa, Tsokyi CHOERA, Anne BEAUVAIS, Francesca FALLARINO, Giuseppe PAOLICELLI, Giuseppe PIERACCINI, Marco PIERONI, Claudia GALOSI, Claudia BEATO, Antonella DE LUCA, Francesca BOSCARO, Riccardo ROMOLI, Xin LIU, Adilia WARRIS, Paul E. VERWEIJ, Eloise BALLARD, Monica BORGHI, Marilena PARIANO, Gabriele COSTANTINO, Mario CALVITTI, Carmine VACCA, Vasilis OIKONOMOU, Marco GARGARO, Alicia Yoke Wei WONG, Louis BOON, Marcel DEN HARTOG, Zdeněk SPÁČIL, Paolo PUCCETTI, Jean-Paul LATGE, Nancy P. KELLER a Luigina ROMANI. Aspergillus fumigatus tryptophan metabolic route differently affects host immunity. Cell Reports. CAMBRIDGE: Cell Press, 2021, roč. 34, č. 4, s. 1-20. ISSN 2211-1247. doi:10.1016/j.celrep.2020.108673.
    4. JHA, Durga, Markéta NEZVEDOVÁ, Tereza VÁŇOVÁ, Lukáš OPÁLKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Characterization of Gangliosides in Cerebral Organoids: A New Avenue to Study Aging and Alzheimer’s Disease-Related Cerebral Changes. In Prague Meeting on Historical Perspectives of Mass Spectrometry, Prague, Czech Republic. 2021.
    5. JHA, Durga, Tereza VÁŇOVÁ, Lukáš OPÁLKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Characterization of membrane lipids in cerebral organoids. In Czech Mass Spectrometry Conference 2021, 9th Conference of CSMS (Czech Society for Mass Spectrometry). 2021.
    6. SPÁČIL, Zdeněk, Markéta NEZVEDOVÁ, Darshak Chandulal GADARA, Durga JHA a Eliška BENEŠOVÁ. Mass Spectrometry Quantitative Proteomics and Exploratory Metabolomics for Biomarker Discovery. In Prague Meeting on Historical Perspectives of Mass Spectrometry, Prague, Czech Republic. 2021.
    7. NEZVEDOVÁ, Markéta, Tereza VÁŇOVÁ, Jan RAŠKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Mass spectrometry-based targeted assay for profiling cell-specific and neurodegeneration protein markers in a single cerebral organoid. In XXVI. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with cooperation of Austrian and German Biochemical Section, České Budějovice, Czech Republic. 2021.
    8. NEZVEDOVÁ, Markéta, Tereza VÁŇOVÁ, Jan RAŠKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Mass Spectrometry-Based Targeted Assay for Profiling Cell-Specific, Developmental and Neurodegeneration Protein Markers in a Single Cerebral Organoid. In Prague Meeting on Historical Perspectives of Mass Spectrometry, Prague, Czech Republic. 2021.
    9. BOSÁK, Juraj, Matej LEXA, Kristýna FIEDOROVÁ, Darshak Chandulal GADARA, Lenka MICENKOVÁ, Zdeněk SPÁČIL, Jiří LITZMAN, Tomáš FREIBERGER a David ŠMAJS. Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates. Frontiers in Immunology. LAUSANNE: FRONTIERS MEDIA SA, 2021, roč. 12, May 2021, s. 1-13. ISSN 1664-3224. doi:10.3389/fimmu.2021.671239.
    10. COSTANTINI, Claudio, Emilia NUNZI, Angelica SPOLZINO, Melissa PALMIERI, Giorgia RENGA, Teresa ZELANTE, Lukas ENGLMAIER, Kateřina COUFALÍKOVÁ, Zdeněk SPÁČIL, Monica BORGHI, Marina M. BELLET, Enzo ACERBI, Matteo PUCCETTI, Stefano GIOVAGNOLI, Roberta SPACCAPELO, Vincenzo N. TALESA, Giuseppe LOMURNO, Francesco MERLI, Luca FACCHINI, Antonio SPADEA, Lorella MELILLO, Katia CODELUPPI, Francesco MARCHESI, Gessica MARCHESINI, Daniela VALENTE, Giulia DRAGONETTI, Gianpaolo NADALI, Livio PAGANO, Franco AVERSA a Luigina ROMANI. Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients. INFECTION AND IMMUNITY. WASHINGTON: The American Society for Microbiology, 2021, roč. 89, č. 8, s. 1-17. ISSN 0019-9567. doi:10.1128/IAI.00105-21.
    11. NEZVEDOVÁ, Markéta, Tereza VÁŇOVÁ, Jan RAŠKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Profiling cell-specific, developmental, and neurodegeneration protein markers in a single cerebral organoid. In 69th ASMS Conference on Mass Spectrometry and Allied Topics, Philadelphia, USA, online. 2021.
    12. NEZVEDOVÁ, Markéta, Tereza VÁŇOVÁ, Jan RAŠKA, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Profiling cell-specific, developmental and neurodegenerative protein markers in cerebral organoids. In Czech Mass Spectrometry Conference 2021, 9th Conference of CSMS (Czech Society for Mass Spectrometry), Prague, Czech Republic. 2021.
    13. AUST, Anne-Christine, Eliška BENEŠOVÁ, Veronika VIDOVÁ, Kateřina COUFALÍKOVÁ, Soňa SMETANOVÁ, Ivo BOREK, Petr JANKŮ, Eva BUDINSKÁ, Jana KLÁNOVÁ, Vojtěch THON a Zdeněk SPÁČIL. Profiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens. Frontiers in Microbiology. Switzerland: Frontiers Research Foundation, 2021, roč. 12, October 2021, s. 1-16. ISSN 1664-302X. doi:10.3389/fmicb.2021.665743.
    14. VIDOVÁ, Veronika, Eliška BENEŠOVÁ, Jana KLÁNOVÁ, Vojtěch THON a Zdeněk SPÁČIL. Simultaneous quantitative profiling of clinically relevant immune markers in neonatal stool swabs to reveal inflammation. Nature Scientific Reports. London: NATURE RESEARCH, 2021, roč. 11, č. 1, s. 1-9. ISSN 2045-2322. doi:10.1038/s41598-021-89384-0.
    15. GADARA, Darshak Chandulal, Kateřina COUFALÍKOVÁ, Juraj BOSÁK, David ŠMAJS a Zdeněk SPÁČIL. Systematic Feature Filtering in Exploratory Metabolomics: Application toward Biomarker Discovery. Analytical chemistry. WASHINGTON: AMER CHEMICAL SOC, 2021, roč. 93, č. 26, s. 9103-9110. ISSN 0003-2700. doi:10.1021/acs.analchem.1c00816.

    2020

    1. PAVLOVÁ, Tereza, Zdeněk SPÁČIL, Veronika VIDOVÁ, Filip ZLÁMAL, Eliška ČECHOVÁ, Zuzana HODICKÁ a Julie DOBROVOLNÁ. Adipophilin and perilipin 3 positively correlate with total lipid content in human breast milk. Scientific reports. London: Nature Publishing Group, 2020, roč. 10, č. 1, s. 1-9. ISSN 2045-2322. doi:10.1038/s41598-019-57241-w.

    2019

    1. NEZVEDOVÁ, Markéta, Eliška BENEŠOVÁ, Veronika VIDOVÁ, Gabriela PŘIBYL DOVRTĚLOVÁ, Tereza VÁŇOVÁ, Dáša BOHAČIAKOVÁ a Zdeněk SPÁČIL. Expression of cellular and neurodevelopmental markers in cerebral organoids. In 6th Annual Congress in Clinical Mass Spectrometry - MSACL 2019 EU, Salzburg, Austria. 2019.
    2. VIDOVÁ, Veronika, Eliška STUCHLÍKOVÁ, Markéta VRBOVÁ, Martina ALMÁŠI, Jana KLÁNOVÁ, Vojtěch THON a Zdeněk SPÁČIL. Multiplex Assay for Quantification of Acute Phase Proteins and Immunoglobulin A in Dried Blood Spots. Journal of Proteome Research. Washington, USA: AMER CHEMICAL SOC, 2019, roč. 18, č. 1, s. 380-391. ISSN 1535-3893. doi:10.1021/acs.jproteome.8b00657.

    2018

    1. KUČERA, Jan, Zdeněk SPÁČIL, David FRIEDECKÝ, Jan NOVÁK, Matej PEKAŘ a Julie BIENERTOVÁ VAŠKŮ. Human White Adipose Tissue Metabolome: Current Perspective. OBESITY. HOBOKEN: WILEY, 2018, roč. 26, č. 12, s. 1870-1878. ISSN 1930-7381. doi:10.1002/oby.22336.

    2017

    1. VIDOVÁ, Veronika a Zdeněk SPÁČIL. A review on mass spectrometry-based quantitative proteomics: Targeted and data independent acquisition. Analytica Chimica Acta. Amsterdam: Elsevier Science publishers, 2017, roč. 964, April, s. 7-23. ISSN 0003-2670. doi:10.1016/j.aca.2017.01.059.
    2. LIAO, Hsuan-Chieh, Zdeněk SPÁČIL, Farideh GHOMASHCHI, Maria L. ESCOLAR, Joanne KURTZBERG, Joseph J. ORSINI, Frantisek TURECEK, C. Ronald SCOTT a Michael H. GELB. Lymphocyte Galactocerebrosidase Activity by LC-MS/MS for Post-Newborn Screening Evaluation of Krabbe Disease. Clinical Chemistry. Washington, USA: AMER ASSOC CLINICAL CHEMISTRY, 2017, roč. 63, č. 8, s. 1363-1369. ISSN 0009-9147. doi:10.1373/clinchem.2016.264952.
    3. PAVLOVÁ, Tereza, Veronika VIDOVÁ, Julie BIENERTOVÁ VAŠKŮ, Petr JANKŮ, Martina ALMÁŠI, Jana KLÁNOVÁ a Zdeněk SPÁČIL. Urinary intermediates of tryptophan as indicators of the gut microbial metabolism. Analytica Chimica Acta. Amsterdam: Elsevier Science, 2017, roč. 987, September, s. 72-80. ISSN 0003-2670. doi:10.1016/j.aca.2017.08.022.

    2016

    1. SPÁČIL, Zdeněk, AB KUMAR, HC LIAO, C AURAY-BLAIS, S STARK, TR SUHR, CR SCOTT, F TURECEK a MH GELB. Sulfatide Analysis by Mass Spectrometry for Screening of Metachromatic Leukodystrophy in Dried Blood and Urine Samples. Clinical Chemistry. Washington, USA: Amer. Assoc. Clinical Chemistry, 2016, roč. 62, č. 1, s. 279-286. ISSN 0009-9147. doi:10.1373/clinchem.2015.245159.

    2015

    1. KUMAR, AB, Zdeněk SPÁČIL, F GHOMASHCHI, S MASI, T SUMIDA, M ITO, F TURECEK, CR SCOTT a MH GELB. Fluorimetric assays for N-acetylgalactosamine-6-sulfatase and arylsulfatase B based on the natural substrates for confirmation of mucopolysaccharidoses types IVA and VI. Clinica Chimica Acta. AMSTERDAM: ELSEVIER SCIENCE BV, 2015, roč. 451, s. 125-128. ISSN 0009-8981. doi:10.1016/j.cca.2015.08.010.
    2. KUMAR, AB, S MASI, F GHOMASHCHI, NK CHENNAMANENI, M ITO, CR SCOTT, F TURECEK, MH GELB a Zdeněk SPÁČIL. Tandem Mass Spectrometry Has a Larger Analytical Range than Fluorescence Assays of Lysosomal Enzymes: Application to Newborn Screening and Diagnosis of Mucopolysaccharidoses Types II, IVA, and VI. Clinical Chemistry. Washington, USA: Amer. Assoc. Clinical Chemistry, 2015, roč. 61, č. 11, s. 1363-1371. ISSN 0009-9147. doi:10.1373/clinchem.2015.242560.

    2014

    1. JIANG, LY, P DZIEDZIC, Zdeněk SPÁČIL, GL ZHAO, L NILSSON, LL ILAG a A CORDOVA. Abiotic synthesis of amino acids and self-crystallization under prebiotic conditions. Scientific Reports. LONDON: NATURE PUBLISHING GROUP, 2014, roč. 4, 6 s. ISSN 2045-2322. doi:10.1038/srep06769.
    2. CHENNAMANENI, NK, AB KUMAR, M BARCENAS, Zdeněk SPÁČIL, CR SCOTT, F TURECEK a MH GELB. Improved Reagents for Newborn Screening of Mucopolysaccharidosis Types I, II, and VI by Tandem Mass Spectrometry. Analytical Chemistry. WASHINGTON: AMER CHEMICAL SOC, 2014, roč. 86, č. 9, s. 4508-4514. ISSN 0003-2700. doi:10.1021/ac5004135.

    2013

    1. SPÁČIL, Zdeněk, H TATIP2AKA, M BARCENAS, CR SCOTT, F TURECEK a MH GELB. High-Throughput Assay of 9 Lysosomal Enzymes for Newborn Screening. Clinical Chemistry. Washington, USA: Amer. Assoc. Clinical Chemistry, 2013, roč. 59, č. 3, s. 502-511. ISSN 0009-9147. doi:10.1373/clinchem.2012.189936.

    2012

    1. JIANG, LY, B AIGRET, Borggraeve WM DE, Zdeněk SPÁČIL a LL ILAG. Selective LC-MS/MS method for the identification of BMAA from its isomers in biological samples. Analytical and Bioanalytical chemistry. HEIDELBERG: SPRINGER HEIDELBERG, 2012, roč. 403, č. 6, s. 1719-1730. ISSN 1618-2642. doi:10.1007/s00216-012-5966-y.

    2011

    1. SPÁČIL, Zdeněk, S ELLIOTT, SL REEBER, MH GELB, CR SCOTT a F TURECEK. Comparative Triplex Tandem Mass Spectrometry Assays of Lysosomal Enzyme Activities in Dried Blood Spots Using Fast Liquid Chromatography: Application to Newborn Screening of Pompe, Fabry, and Hurler Diseases. Analytical Chemistry. WASHINGTON: AMER CHEMICAL SOC, 2011, roč. 83, č. 12, s. 4822-4828. ISSN 0003-2700. doi:10.1021/ac200417u.

    2010

    1. JONASSON, S, J ERIKSSON, L BERNTZON, Zdeněk SPÁČIL, LL ILAG, LO RONNEVI, U RASMUSSEN a B BERGMAN. Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure. Proceedings of the National Academy of Sciences of the United States of America. WASHINGTON: National Academy of Sciences, 2010, roč. 107, č. 20, s. 9252-9257. ISSN 0027-8424. doi:10.1073/pnas.0914417107.
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