Výpis publikací

VEVERKA, Pavel, Tomáš BROM, Tomáš JANOVIČ, Martin STOJASPAL, Matyáš PINKAS, Jiří NOVÁČEK a Ctirad HOFR. Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST – RE1-silencing transcription factor. Computational and Structural Biotechnology Journal. Elsevier, 2023, roč. 21, Dec, s. 731-741. ISSN 2001-0370. Dostupné z: https://dx.doi.org/10.1016/j.csbj.2022.12.026.

BROM, Tomáš, Martin STOJASPAL, Tomáš JANOVIČ, Ivona NEČASOVÁ, Pavel VEVERKA a Ctirad HOFR. Insight into inherited anemia CDA-I: disease-associated mutations disrupt Codanin1-CDIN1 complex. In XIX Discussions in Structural Molecular Biology and 6th User Meeting of the Czech Infrastructure for Integrative Structural Biology. 2023.

STORCHOVA, Radka, Matouš PALEK, Natálie PALKOVA, Pavel VEVERKA, Tomáš BROM, Ctirad HOFR a Libor MACŮREK. Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. Nucleic Acids Research. Oxford University Press, 2023, roč. 51, č. 3, s. 1154-1172. ISSN 0305-1048. Dostupné z: https://dx.doi.org/10.1093/nar/gkac1269.

BROM, Tomáš, Martin STOJASPAL, Tomáš JANOVIČ, Ivona NEČASOVÁ, Pavel VEVERKA a Ctirad HOFR. Codanin1 and CDIN1 interaction: implications for inherited anemia progression. In XXI. setkání biochemiků a molekulárních biologů. 2022. ISBN 978-80-280-0136-0.

BROM, Tomáš, Tomáš JANOVIČ, Pavel VEVERKA, Martin STOJASPAL a Ctirad HOFR. Critical interactions of neuronal transcription factor REST with stabilizer TRF2. 2022.

KUČERA, Josef, Ondřej PEŠ, Tomáš JANOVIČ, Ctirad HOFR, Lenka KUBINYIOVÁ, Ján TÓTH, Štěpán KÁŇA a Petr TÁBORSKÝ. Enhancement of luminescence signal by deuterated water - Practical implications. Sensors and Actuators B: Chemical. Amsterdam: Elsevier B.V., 2022, roč. 352, č. 1, s. 1-8. ISSN 0925-4005. Dostupné z: https://dx.doi.org/10.1016/j.snb.2021.131029.

BROM, Tomáš, Tomáš JANOVIČ, Martin STOJASPAL, Eliška KŮŘILOVÁ, Simona CHLUDILOVÁ a Ctirad HOFR. Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy. In 1st MOSBRI Scientific Conference. 2022. Dostupné z: https://dx.doi.org/.

BROM, Tomáš, Tomáš JANOVIČ, Martin STOJASPAL, Eliška KŮŘILOVÁ, Simona CHLUDILOVÁ a Ctirad HOFR. Essential transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy. In Instruct Biennial Structural Biology Conference. 2022.

RAYMOND MARIO, Barry, Olivia SACCO, Amel MAMERI, Martin STOJASPAL, William KARTSONIS, Pooja SHAH, Pablo DE IOANNES, Ctirad HOFR, Jacques CÔTÉ a Agnel SFEIR. Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states. Genes & Development. Cold Spring Harbor Laboratory Press, 2022, roč. 36, 5-6, s. 313-330. ISSN 0890-9369. Dostupné z: https://dx.doi.org/10.1101/gad.349039.121.

NEČASOVÁ, Ivona, Martin STOJASPAL, Edita MOTYČÁKOVÁ, Tomáš BROM, Tomáš JANOVIČ a Ctirad HOFR. Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy. NAR Cancer. Oxford University Press, 2022, roč. 4, č. 1, s. 1-16. ISSN 2632-8674. Dostupné z: https://dx.doi.org/10.1093/narcan/zcac005.

HOFR, Ctirad, Pavel VEVERKA, Tomáš BROM a Tomáš JANOVIČ. When TRF2 is around, REST is in peace - Structural and functional implications of extratelomeric TRF2 protecting neuronal differentiation regulator REST in glioblastoma. In EMBO Workshop on Telomere function and evolution in health and disease 26 September-01 October 2022 | Tróia, Portugal. 2022.

JANOVIČ, Tomáš, Martin STOJASPAL, Pavel VEVERKA a Ctirad HOFR. Assembly of human guardians of telomeres: TRF1 exchanges TRF2 bound to TIN2 but tolerates TRF2 in TPP1 presence. In CEITEC PhD Conference. 2021.

JANOVIČ, Tomáš, Tomáš BROM, Martin STOJASPAL, Pavel VEVERKA, Denisa HORÁKOVÁ a Ctirad HOFR. Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 When TPP1 Is Absent. In 26th International Workshop on “Single Molecule Spectroscopy and Super-resolution Microscopy”. 2021.

JANOVIČ, Tomáš a Ctirad HOFR. Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent. In CEITEC PhD Conference. 2020.

BROM, Tomáš, Martin STOJASPAL, Tomáš JANOVIČ, Pavel VEVERKA a Ctirad HOFR. Molecular mechanism of glioblastoma cell differentiation. In FEBS INSTRUCT MOBIEU Practical course: Hydrodynamic and ther- modynamic analysis of biological macromolecules and their interactions. 2020.

JANOVIČ, Tomáš, Martin STOJASPAL, Pavel VEVERKA, Denisa HORÁKOVÁ a Ctirad HOFR. Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent. Journal of Molecular Biology. London: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2019, roč. 431, č. 17, s. 3289-3301. ISSN 0022-2836. Dostupné z: https://dx.doi.org/10.1016/j.jmb.2019.05.038.

VEVERKA, Pavel, Tomáš JANOVIČ a Ctirad HOFR. Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point. International Journal of Molecular Sciences. Basel: Multidisciplinary Digital Publishing Institute, 2019, roč. 20, č. 13, s. 1-13. ISSN 1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms20133186.

STOJASPAL, Martin, Tomáš JANOVIČ, Pavel VEVERKA a Ctirad HOFR. DYNAMICS OF REST-TRF2 INTERACTIONS AND THE FATE OF NEURAL CANCER CELLS. Online. In František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník, Jan Přikryl. 15 th International Interdisciplinary Meeting on Bioanalysis. Brno: Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic, 2018, s. 276-282. ISBN 978-80-904959-7-5.

HOFR, Ctirad, Ivona NEČASOVÁ, Eliška JANOUŠKOVÁ, Tomáš JANOVIČ, Martin STOJASPAL a Pavel VEVERKA. HOW TO TRAIN OUR CELLS TO BECOME YOUNGER – QUANTITATIVE BIOPHYSICS OF HUMAN TELOMERASE AND ITS GUARD SHELTERIN. Online. In František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník, Jan Přikryl. 15 th International Interdisciplinary Meeting on Bioanalysis - Conference Proceedings. Česká republika: Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic, 2018, s. 59-63. ISBN 978-80-904959-7-5.

JANOVIČ, Tomáš, Martin STOJASPAL, Pavel VEVERKA, Denisa HORÁKOVÁ a Ctirad HOFR. Human TRF1 exchanges TRF2 bound to TIN2 but tolerates TRF2 in TPP1 presence. In EMBO Workshop, Telomere biology in health and human disease 1-6 May 2018, Tróia, Portugal. 2018.

HOFR, Ctirad. Medgenet Summer School. 2018.

VEVERKA, Pavel, Martin STOJASPAL, Tomáš JANOVIČ a Ctirad HOFR. Purification of human telomerase TEN domain and its interaction partner TPP1. Online. In František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník, Jan Přikryl. 15 th International Interdisciplinary Meeting on Bioanalysis. Brno: Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic, 2018, s. 210-215. ISBN 978-80-904959-7-5.

HOFR, Ctirad, Ivona NEČASOVÁ a Eliška JANOUŠKOVÁ. Rap1 and TRF2 in D-loop unwinding and telomere finding. In EMBO workshop, Telomere biology and human disease 1-6 May 2018, Tróia, Portugal. 2018.

NEČASOVÁ, Ivona, Eliška JANOUŠKOVÁ, Tomáš KLUMPLER a Ctirad HOFR. Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it. Nucleic Acids Research. 2017, roč. 45, č. 21, s. 12170-12180. ISSN 0305-1048. Dostupné z: https://dx.doi.org/10.1093/nar/gkx812.

NEČASOVÁ, Ivona, Eliška JANOUŠKOVÁ, Tomáš KLUMPLER a Ctirad HOFR. Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it (gkx812) (vol 45, pg 12170, 2017). Oxford: Oxford University Press, 2017. Dostupné z: https://dx.doi.org/10.1093/nar/gkx968.

VALUCHOVÁ, Soňa, Jaroslav FULNEČEK, Zbyněk PROKOP, Peggy STOLT-BERGNER, Eliška JANOUŠKOVÁ, Ctirad HOFR a Karel ŘÍHA. Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer. Plant Cell. ROCKVILLE: AMER SOC PLANT BIOLOGISTS, 2017, roč. 29, č. 6, s. 1533-1545. ISSN 1040-4651. Dostupné z: https://dx.doi.org/10.1105/tpc.17.00064.

SEPSIOVA, Regina, Ivona NEČASOVÁ, Smaranda WILLCOX, Katarina PROCHAZKOVA, Peter GORILÁK, Jozef NOSEK, Ctirad HOFR, Jack D. GRIFFITH a Ĺubomír TOMÁŠKA. Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins. Plos one. San Francisco: Public Library of Science, 2016, roč. 11, č. 4, s. 1-17. ISSN 1932-6203. Dostupné z: https://dx.doi.org/10.1371/journal.pone.0154225.

DALBY, AB, Ctirad HOFR a TR CECH. Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase. Journal of Molecular Biology. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2015, roč. 427, č. 6, s. 1291-1303. ISSN 0022-2836. Dostupné z: https://dx.doi.org/10.1016/j.jmb.2015.01.008.

JANOUŠKOVÁ, Eliška, Ivona NEČASOVÁ a Ctirad HOFR. How human Rap1 prompts more accurate and selective TRF2 recognition of telomeric DNA? In EMBO Workshop Telomeric chromatin and telomere fragility. 2015.

JANOUŠKOVÁ, Eliška, Ivona NEČASOVÁ, Jana PAVLOUŠKOVÁ, Michal ZIMMERMANN, Milan HLUCHÝ, María Victoria MARINI PALOMEQUE, Monika NOVÁKOVÁ a Ctirad HOFR. Human Rap1 modulates TRF2 attraction to telomeric DNA. Nucleic Acids Research. Oxford: Oxford University Press, 2015, roč. 43, č. 5, s. 2691-2700. ISSN 0305-1048. Dostupné z: https://dx.doi.org/10.1093/nar/gkv097.

NEČASOVÁ, Ivona, Tomáš KLUMPLER, Karel KUBÍČEK a Ctirad HOFR. Revisiting the role of TRF2 basic domain in chromatin maintenance with the most recent structural and functional approaches. In EMBO Workshop Telomeric chromatin and telomere fragility. 2015.

JANOUŠKOVÁ, Eliška, Ivona NEČASOVÁ a Ctirad HOFR. How Rap1 Affects TRF2 Recognition of Telomeres? In XVI. Setkání biochemiků a molekulárních biologů. 2014. ISBN 978-80-210-7340-1.

NEČASOVÁ, Ivona, Michal ZIMMERMANN a Ctirad HOFR. How specific is TRF2 binding to telomeric DNA? In EMBO conference Telomeres, telomerase and disease. 2014.

JANOUŠKOVÁ, Eliška, Ivona NEČASOVÁ, Michal ZIMMERMANN, Milan HLUCHÝ a Ctirad HOFR. Human Rap1 Induces TRF2 Release from Telomeric DNA. In EMBO Conference Telomeres, Telomerase and disease. 2014.

JANOUŠKOVÁ, Eliška a Ctirad HOFR. How does protein Rap1 affect interactions of its binding partner TRF2? In CSHL: Telomeres & Telomerase. 2013.

NEČASOVÁ, Ivona, Michal ZIMMERMANN a Ctirad HOFR. Impact of N-terminal basic domain of protein TRF2 on its DNA binding affinity. In CSHL: Telomeres & Telomerase. 2013.

BUCHLOVIČ, Marian, Zdeněk KŘÍŽ, Ctirad HOFR a Milan POTÁČEK. New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA. Bioorganic & Medicinal Chemistry. Elsevier, 2013, roč. 21, č. 5, s. 1078-1081. ISSN 0968-0896. Dostupné z: https://dx.doi.org/10.1016/j.bmc.2013.01.004.

POTÁČEK, Milan, Marian BUCHLOVIČ, Zdeněk KŘÍŽ a Ctirad HOFR. Synthesis, activity and interaction of nitrone functionalized PAH derivatives. 2013.

NEČASOVÁ, Ivona, Michal ZIMMERMANN a Ctirad HOFR. N-terminal basic domain of genome guarding telomeric protein TRF2 affects its DNA binding affinity. In EMBO Conference Telomeres and the DNA damage response. 2012.

KUBÍČEK, Karel, Hana ČERNÁ, Peter HOLUB, Josef PASULKA, Dominika HROŠŠOVÁ, Frank LOEHR, Ctirad HOFR, Štěpánka VAŇÁČOVÁ a Richard ŠTEFL. Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. Genes & Development. New York: Cold Spring Harbor Laboratory Press, 2012, roč. 26, č. 17, s. 1891-1896. ISSN 0890-9369. Dostupné z: https://dx.doi.org/10.1101/gad.192781.112.

NEČASOVÁ, Ivona, Michal ZIMMERMANN a Ctirad HOFR. Stanovení vlivu bazické domény lidského telomerového proteinu TRF2 na vazbu k DNA. In XII mezioborové setkání mladých biologů, biochemiků a chemiků z Čech a Slovenska. 2012. ISSN 0009-2770.

VISACKA, Katarina, Ctirad HOFR, Smaranda WILLCOX, Ivona NEČASOVÁ, Jana PAVLOUŠKOVÁ, Regina SEPSIOVA, Michaela WIMMEROVÁ, Lucia SIMONICOVA, Jozef NOSEK, Jiří FAJKUS, Jack D. GRIFFITH a Lubomir TOMASKA. Synergism of the Two Myb Domains of Tay1 Protein Results in High Affinity Binding to Telomeres*. The Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2012, roč. 287, č. 38, s. 32206-32215. ISSN 0021-9258. Dostupné z: https://dx.doi.org/10.1074/jbc.M112.385591.

HÓBOR, Fruzsina, Roberto PERGOLI, Karel KUBÍČEK, Dominika HROŠŠOVÁ, Veronika BAČÍKOVÁ, Michal ZIMMERMANN, Josef PASULKA, Ctirad HOFR, Štěpánka VAŇÁČOVÁ a Richard ŠTEFL. Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (Nab)3 protein. The Journal of Biological Chemistry. Am. Soc. for Biochem. and Mol. Biol., 2011, roč. 286, č. 5, s. 3645-3657. ISSN 0021-9258. Dostupné z: https://dx.doi.org/10.1074/jbc.M110.158774.

ŠTEFL, Richard, Florian OBERSTRASS, Jeniffer HOOD, Muriel JOURDAN, Michal ZIMMERMANN, Lenka SKŘÍŠOVSKÁ, Christophe MARIS, Li PENG, Ctirad HOFR, Ronald EMESON a Frederic ALLAIN. The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove. CELL. UNITED STATES: CELL PRESS, 2010, roč. 143, č. 2, s. 225-237. ISSN 0092-8674.

ZIMMERMANN, Michal, Ctirad HOFR, Pavla ŠULTESOVÁ, Iva MOZGOVÁ, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ a Jiří FAJKUS. Application of fluorescence anisotropy to monitor protein binding to telomeric DNA. In FluoroFest Prague 2009. 2009.

ZIMMERMANN, Michal, Ctirad HOFR, Pavla ŠULTESOVÁ, Iva MOZGOVÁ, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ a Jiří FAJKUS. Mechanismus vazby SMH proteinů na telomerickou DNA. In Chemické listy. Praha: Neuveden, 2009, 2 s. ISSN 0009-2770.

HOFR, Ctirad, Pavla ŠULTESOVÁ, Michal ZIMMERMANN, Iva MOZGOVÁ, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ, Michaela WIMMEROVÁ a Jiří FAJKUS. Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specifity and kinetics. BIOCHEMICAL JOURNAL. ENGLAND: PORTLAND PRESS LTD, 2009, roč. 419, Neuveden, s. 221-228. ISSN 0264-6021.

MOZGOVÁ, Iva, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ, Ctirad HOFR a Jiří FAJKUS. Functional characterization of domains in AtTRB1, a putative telomere-binding protein in Arabidopsis thaliana. Phytochemistry. England: Pergamon-Elsevier Science Ltd, 2008, roč. 69, č. 9, s. 1814-1819. ISSN 0031-9422.

HOFR, Ctirad, Pavla ŠULTESOVÁ, Iva MOZGOVÁ, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ a Jiří FAJKUS. Telomere repeat binding protein variants show distinct kinetics and energetic nature of DNA-protein interaction. In 4th European workshop on: Role of Telomeres and Telomerase in Cancer and Aging. 2008.

ŠANTRŮČKOVÁ, Iva, Ctirad HOFR, Petra SCHRUMPFOVÁ a Jiří FAJKUS. Characterisation of AtTRB1 binding properties. In Plant DNA Repair & Recombination. 2007.

MOZGOVÁ, Iva, Ctirad HOFR, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ a Jiří FAJKUS. Charakterizace vazebných vlastností ATTRB1. In Bulletin České společnosti experimentální biologie rostlin a Fyziologické sekce Slovenské botanické společnosti. OIomouc: Česká společnost experimentální biologie rostlin, 2007, s. 66. ISSN 1213-6670.

KUCHAŘ, Milan, Petra SCHRUMPFOVÁ, Iva ŠANTRŮČKOVÁ, Jan PALEČEK, Ctirad HOFR a Jiří FAJKUS. Mapping of interaction domains of putative plant telomere preteins. In Plant DNA Repair & Recombination. 2007.

HOFR, Ctirad. Mikrokalorimetrie bilogicky významných molekul. Československý časopis pro fyziku. Česká republika: Fyzikální ústav AVČR, 2006, roč. 56, č. 5, s. 288-292. ISSN 0009-0700.

MITCHELL, Edward, Charles SABIN, Lenka ŠNAJDROVÁ, Martina POKORNÁ, Stephanie PERRET, Catherine GAUTIER, Ctirad HOFR, Nechama GILBOA-GARBER, Jaroslav KOČA, Michaela WIMMEROVÁ a Anne IMBERTY. High affinity fucose binding of Pseudomonas aeruginosa lectin PA-IIL: 1.0 A resolution crystal structure of the complex combined with thermodynamics and computational chemistry approaches. Proteins: Structure, Function, and Bioinformatics. Wiley, 2005, roč. 58, č. 3, s. 735-746. ISSN 0887-3585.

BRABEC, Viktor a Ctirad HOFR. Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II). BIOPOLYMERS. 111 RIVER ST, HOBOKEN, NJ 07030 USA: JOHN WILEY & SONS INC, 2005, roč. 77, č. 4, s. 222-229, 9 s. ISSN 0006-3525.

HOFR, Ctirad a Viktor BRABEC. Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2001, roč. 276, č. 276, s. 9655-9661. ISSN 0021-9258.

HOFR, Ctirad, Nicholas FARRELL a Viktor BRABEC. Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex. Nucleic Acids Research. Oxford, UK: Oxford Press, 2001, roč. 29, č. 10, s. 2034-2040. ISSN 0305-1048.

MALINA, Jaroslav, Ctirad HOFR, Lucciana MARESCA, Giovanni NATILE a Viktor BRABEC. DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands. Biophysical Journal. New York, USA: Rockefeller University, 2000, roč. 2000, č. 78, s. 2008-2021. ISSN 0006-3465.

NOVÁKOVÁ, Olga, Ctirad HOFR a Viktor BRABEC. Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl2(Me2SO4)4Ru] in cell-free media. Biochemical Pharmacology. Oxford, UK: Elsevier, 2000, roč. 60, č. 12, s. 1761-1771. ISSN 0006-2952.