aZLFA0722p Pharmacology II - lecture

Faculty of Medicine
autumn 2026
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
MUDr. Alena Máchalová, Ph.D. (lecturer)
Carlos Daniel Ferreira Fonseca, MSc. (assistant)
Mgr. Barbora Říhová, Ph.D. (lecturer)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Prerequisites
aZLFA0621c Pharmacology I - pract. && aZLPA0622c Pathology II - practice && aZLPF0622c Pathophysiol. II - practice && aZLOR0641c Orthodontics I -pract. && aZLPD0631c Periodontology I - practice
The student has completed courses aZLFA0722c, aZLFA0621c, aZLFA0621p, aZLPA0622c, aZLPF0622c, aZLOR0641c, and aZLPD0631c
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
Upon completion of the course, the student will understand the principles of "pharmacological thinking" in drug selection, dosage, pharmacokinetic parameter calculations, choice and technique of administration methods and should be able to master the basic pharmacological profile of selected drug groups.
Learning outcomes
Upon completion of the course, the student will:
- be familiar with medicinal product databases and be able to search for specific medicinal products
- distinguish between different routes of administration and dosage forms of a drug and their advantages and disadvantages
- be able to prescribe Ready-made products
- know the basic pharmacokinetic processes and parameters and can determine the type of mechanism of action of specific drugs
- know the basic pharmacological profile of the drug groups discussed - can recognize drug-drug interactions and can evaluate its severity
Key topics
  • 1. ANALGESICS, PHARMACOTHERAPY OF MIGRAINE AND GOUT. Classification of analgesics. Basic pharmacological characteristics and examples of the use of opioid analgesics, non-steroidal anti-inflammatory drugs and analgesic-antipyretics. Basic principles of pain therapy, co-analgesics. Drugs used in the treatment of migraine and gout.
  • 2. PSYCHOPHARMACOLOGY. Basic pharmacological characteristics of antipsychotics, antiparkinsonian drugs, antidepressants, psychostimulants, anxiolytics, hypnosedatives and anticonvulsants.
  • 3. GENERAL AND LOCAL ANAESTHETICS, MUSCLE RELAXANTS. Classification and basic pharmacological characteristics of general and local anaesthetics and muscle relaxants. Overview of drugs used in premedication and post-anaesthetic care.
  • 4. ANTI-INFECTIVES – ANTIBIOTICS, ANTIMYCOTICS AND ANTIVIROTICS. Principles of rational antimicrobial therapy, bacterial resistance, pharmacological overview of antibiotics, antimycotics and antivirotics.
  • 5. ORAL CAVITY MEDICINES. Summary of general principles. Overview of individual groups and representatives. Pharmacotherapy of selected oral cavity diseases. Phytotherapy in dentistry.
  • 6. DRUGS AFFECTING CARDIOVASCULAR SYSTEM I. Drug groups affecting RAAS (ACEi, sartans, kirens), diuretics, aldosterone antagonists and mineralocorticoid receptor antagonists. First- and second-line antihypertensive drugs, combinations of antihypertensive drugs, vasodilators (calcium channel blockers, nitrates and NO donors).
  • 7. DRUGS AFFECTING CARDIOVASCULAR SYSTEM II AND BLOOD. Positive inotropics and antiarrhythmics. Pharmacological profiles of drugs from the groups of anticoagulants, antiplatelet drugs, fibrinolytics, antifibrinolytics and haemostatics.
  • 8. PHARMACOTHERAPY OF CANCER. Introduction, principles of cytostatic therapy, overview of mechanisms of tumour resistance, importance of genotyping of polymorphisms and TDM in oncology, basic groups of cytostatics/classification according to their mechanism of action, basic pharmacological overview. Principles of targeted therapy in oncology – monoclonal antibodies, tyrosine kinase inhibitors, targeted immunotherapy.
Study resources and literature
    required literature
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
    not specified
  • Lippincott's Illustrated Reviews : Pharmacology, 4th Ed., Harvey, Richard A. - Champe, Pamela C. - Finkel, Richard - Cubeddu, Luigi - Clarke, Michelle A. 2008. 560 s. ISBN-10: 0-7817-7155-2, ISBN-13: 978-0-7817-7155-9
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmaceutical Practice. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone. , 3rd Ed. 2004. ISBN 0443 07206 X
Bookmarks
https://is.muni.cz/ln/tag/LF:aZLFA0722p!
Approaches, practices, and methods used in teaching
Lectures are provided to students in the form of recorded presentations accompanied by audio commentary by the lecturer.
Method of verifying learning outcomes and course completion requirements

The final exam consists of written and oral part.

The final evaluation of the course also contains results of the tests from practicals of both semesters and results of the colloquium test.

The final mark is calculated by the following method:
The relative weight of the mark from tests: 30 %
The relative weight of the mark from the oral exam: 70 %

Written part of the final exam is represented by the ROPOT test that consists of 30 questions (3 points each) undertaken on the day of the final exam. The minimum to pass the test is at least 54 points. If the student fails in the ROPOT, the final exam classification is F. The test can be repeated twice. If students fail in all three attempts in the ROPOT, they can ask the guarantee of the course for a commission oral examination, and the minimal score from the test is used to calculate the final mark.

The ROPOT test has not to be repeated once the student passes it, and in repeated oral examination, the exam starts with the oral part.

In the oral part, the student draws one question of each of three examination question sets and answers the additional questions of the examiner. 

The relative weights of each examination dataset are as follows: General pharmacology: 25 %; Special pharmacology: 25 %; Selected chapters from special pharmacology: 30 %; Additional questions given by examiner: 20 %. In case a student fails in one of the partial questions, the final mark will be F also.

The mark for the tests is given as follows:
A = 181-210 points
B = 161-180 points
C = 141-160 points
D = 126-140 points
E = 110-125 points
F = less than 110 points
Alternate completion
The course is available online. The credits will be given after final examination.
Language of instruction
English
Study support
https://is.muni.cz/auth/el/1411/podzim2026/aZLFA0722p/
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught every week.
Listed among pre-requisites of other courses

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Teacher's information
https://is.muni.cz/auth/el/1411/podzim2026/aZLFA0722p/
The lectures of the course aZLFA0722p are in the form of records inserted into the interactive syllabi of the course aZLFA0722c; questions, comments, and consultations can be given during the following seminars or by email directly to the author of the record. The list of exam questions can be found in the Study materials of this course and are also uploaded to the Interactive syllabi of course aZLFA0722c.
The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024, autumn 2025.
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