ZLPA0521p Pathology I - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
2/0/0. 0 credit(s). Type of Completion: -.
Teacher(s)
doc. MUDr. Jiří Wotke, CSc. (lecturer)
prof. MUDr. Markéta Hermanová, Ph.D. (lecturer)
MUDr. Víta Žampachová (lecturer)
MUDr. Karel Veselý, Ph.D. (lecturer)
MUDr. Pavla Rotterová, Ph.D. (lecturer)
Eva Benešová (assistant)
Guaranteed by
doc. MUDr. Josef Feit, CSc.
First Department of Pathology - Institutions shared with St. Anne's Faculty Hospital - Faculty of Medicine
Contact Person: doc. MUDr. Jiří Wotke, CSc.
Timetable
Wed 13:30–15:10 N01008
Prerequisites (in Czech)
ZLFY0422p Physiology II - lecture && ZLBC041p Biochemistry II -l && ZLAN0333p Anatomy III - lect. && ZLHE0322p Hist.and Embryol.II-lect. && ( ZLLT0222s Bas.Med.Terminology II-sem. || ZLLT0222p Bas. Med. Terminology -l ) && ZLET021p Ethics in Dent.-lect.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main stress in the pathology course is given on macroscopic and microscopic correlation of diseases. After finishing the course the student should be able to: understand the basic pathologic processes (regressive changes, inflammaton, oncology, immune disorders); understand and be able to apply the basic classification of oncologic processes; understand the basic classification of etiologically defined processes (esp. infectious diseases); learn the most important methods used in diagnostic process and research (tissue processing, special stainings, histochemistry, immunohistochemistry, electron microscopy, molecular pathology); understand various disorders with respect to individual organs and organ systems; get familiar with the process of autopsy (the process of the autopsy and its evaluation); get familiar with laboratory processing of the tissue samples (description, tissue sampling);
Syllabus
  • General Pathology
  • Pathology and its role in medicine.
  • Methodology: autopsy, clinico-pathological correlation, surgical pathology (biopsy), ways of tissue examination and fixation
  • Cytology.
  • The disease, its definition and course. External and internal causes of a disease. Prevention.
  • Death (clinical and biological). Signs of death.
  • Regressive changes, necrosis (classification, causes). Atrophy: numeric and simple. Dystrophy: metabolic disorders of proteins, glycids, fat, water, minerals and pigments.
  • Inflammation: definition, local and general sings, microscopic and macroscopic. Inflammation: classification, nomenclature. Immunity disorders, transplantation pathology.
  • Progressive changes. Regeneration, reparation, wound healing. Hypertrophy, hyperplasia, metaplasia, dysplasia. Pseudotumors: cysts, pseudocysts, inflammatory pseudotumor. Disorders of embryonal development.
  • Tumors: definition, general properties, etiology, precanceroses. Biology of tumors: benign, malignant and uncertain tumors. Systematic classification of tumors: epithelial, mesenchymal, neuroectodermal and germinal tumors, choriocarcinoma, mesothelioma. Organ pathology
  • Disorders of the heart, circulation of the blood and lymph: Congenital and acquired heart diseases, changes in size and shape of the heart. Pathological contents of the pericardium. Inflammation, ischemic heart disease, myocardial infarction. Circulatory failure. Hypertension. Disorders of arteries and veins: atherosclerosis, aneurysm, inflammation, anemia, polycytemia. Local circulatory disorders: thrombosis, embolism. Bleeding. Lymfadenitis. Tumors.
  • Respiratory disorders: Pathology of upper respiratory pathways: rhinitis, laryngitis, bronchitis. Tumors and pseudotumors. Changes in pulmonary ventilation and circulation (venostasis, edema, induration, infarction, embolism). Silicosis and other external pigmentations. Superficial, interstitial and chronic inflammations of the lung. Pulmonary tumors. Pathology of the pleura.
  • Disorders of the gastrointestinal tract: Pathology of the oral cavity, pharynx, tonsillae and esophagus. Gastiris, peptic ulcers, gastric tumors. Pathology of the gut: disorders of circulation, inflammation. Appendicitis, malabsorption syndrome. Ileus, herniation. Intestinal tumors. Inflammation of the peritoneum, pathological contents of peritoneal cavity.
Literature
  • MAČÁK, Jiří. Obecná patologie. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2002. 189 s. ISBN 8024404362. info
  • MAČÁK, Jirka and Jana MAČÁKOVÁ. Patologie (Pathology). první. Praha: GRADA, 2004. 347 pp. ISBN 80-247-0785-3. info
  • BUČEK, Jan. Praktikum z patologie :pitevní cvičení. 4. přepr. vyd. Brno: Masarykova univerzita, 1993. 88 s. ISBN 80-210-0721-4. info
  • FEIT, Josef, P. MIŘEJOVSKÝ and I. STEINER. Kontrolní otázky z patologie (Test question in pathology). 1st ed. Praha: Triton, 1998. ISBN 80-85875-89-6. info
Assessment methods
Lectures: 3 hours/week
Practicals: microscopic and autoptic lessons, compulsory; knowledge of the students will be periodically tested
Lectures and practicals are complementary. General information and new updates on classifications as well as images are presented at the lectures. Practicals add further information, histopathologicaly and autoptical experience. Further information is provided in our web-based teaching materials.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Teacher's information
http://www.muni.cz/atlases
The course is also listed under the following terms Autumn 2006, Autumn 2007, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021.
  • Enrolment Statistics (Autumn 2008, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2008/ZLPA0521p