STIM051p Immunology-lecture

Faculty of Medicine
Autumn 2006
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Jindřich Lokaj, CSc. (lecturer)
Miroslava Bučková (assistant)
Guaranteed by
prof. MUDr. Jindřich Lokaj, CSc.
Department of Clinical Immunology and Allergology - Institutions shared with St. Anne's Faculty Hospital - Faculty of Medicine
Contact Person: prof. MUDr. Jindřich Lokaj, CSc.
Prerequisites (in Czech)
VSBC0221p Biochemistry I -lect. && VSLC011p Med.Chem.- lecture && VSBI0222p Biology II - lecture && ( VSBF011p Biophysics || STBF011p Biophysics ) && VSFY0422s Physiology II - seminar && VSFY0422p Physiology II - lecture && VSBC041s Biochemistry II -s && VSBC041c Biochemistry II -pract. && VSLT0221s Bas. Med. Terminol. II -s && VSET021 Medical ethics
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Syllabus
  • Immunology in medicine.
  • Anatomy and cellular elements of the immune system.
  • Immune mechanisms. Innate and acquired immunity.
  • Innate or natural immunity: phagocytosis, NK cells, cytotoxicity, interferon system, complement system, acute phase reaction, inflammation.
  • B lymphocytes and immunoglobulins.
  • Genetic basis of immunoglobulin heterogeneity.
  • Biological properties of antibodies.
  • Monoclonal antibodies as diagnostic and therapeutic tools.
  • T-lymphocytes, their development and effector functions.
  • Polarisation of T-lymphocytes (T1, T2). Cytotoxicity. Cytokines.
  • Major histocompatibility complex: structure, function.
  • Activation of T and B cells by antigen.
  • Interactions between antigen-presenting cells and T- and B-lymphocytes.
  • Regulation of the immune reaction.
  • Mucosal immunity.
  • Immunity against infection agents. Microbial antigens.
  • Active and passive immunisation.
  • Primary and secondary immunodeficiency disorders.
  • HIV disease.
  • Immunoglobulin therapy. Immunostimulation.
  • Autoimmunity and disease. Immunological tolerance.
  • Autoantibodies and their laboratory detection.
  • Hypersensitivity reactions - anaphylactic, cytotoxic, immune complex, T-cell-mediated.
  • Clinical allergology. Allergic skin and exposition tests.
  • Ontogenesis of the immune system. Immunity in pregnancy. Reproduction immunology.
  • Immunologic disorders in infants and children. Immunity in elderly.
  • Tumor immunology. Tumor antigens. Immune response to tumors. Immunodiagnosis of tumors. Immune-related malignancies.
  • Transfusion immunology. ABO system. Rh system. Transfusion reactions.
  • Immunology of organ and bone marrow transplantation. Graft vs. host reaction.
Literature
  • HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. Vyd. 1. V Praze: Triton, 1998. 219 s. ISBN 80-85875-73-X. info
  • BUC, Milan. Imunológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2001. 463 s. ISBN 8022406678. info
  • FUČÍKOVÁ, Terezie. Základy klinické imunologie :imunodeficity - autoimunita - alergie. [1. vyd.]. Praha: RDI PRESS, 1994. 148 s. ISBN 80-900674-3-3. info
  • Imunológia :základné termíny a definície. Edited by Miroslav Ferenčík - Jozef Rovenský - Štefan Nyulassy. 2. preprac. a dopl. vyd. Bratislava: Slovac Academic Press, 2001. 348 s. ISBN 80-88908-77-9. info
  • Immunology :a short course. Edited by Eli Benjamini - Sidney Leskowitz. 2nd ed. New York: Wiley-Liss, 1991. xxvi, 459. ISBN 0-471-56751-5. info
  • Položky 3 a 4 jsou doplňkovou literaturou
Assessment methods (in Czech)
Závěrečná rigorózní ústní zkouška
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005.
  • Enrolment Statistics (recent)
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