LF:VLBC0422s Biochemistry II sem - Course Information
VLBC0422s Biochemistry I - seminarFaculty of Medicine
- Extent and Intensity
- 0/3/0. 2 credit(s). Type of Completion: z (credit).
- Ing. Martina Čarnecká, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
MUDr. Lenka Gescheidtová, Ph.D. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (seminar tutor)
MUDr. Miroslava Hlaváčová, Ph.D. (seminar tutor)
PharmDr. Katarína Kostolanská (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
Mgr. Lucie Novotná (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Mgr. Anna Pleskačová, Ph.D. (seminar tutor)
MUDr. RNDr. Michal Řiháček, Ph.D. (seminar tutor)
Mgr. Roman Sándor, Ph.D. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Lenka Nerudová (assistant)
- Guaranteed by
- prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Supplier department: Department of Biochemistry - Theoretical Departments - Faculty of Medicine
- Timetable of Seminar Groups
- VLBC0422s/01: Thu 13:30–16:00 A16/213, M. Králíková
VLBC0422s/02: Thu 13:30–16:00 A16/213, M. Králíková
VLBC0422s/03: Thu 13:30–16:00 A16/213, E. Táborská
VLBC0422s/04: Thu 13:30–16:00 A16/213, E. Táborská
VLBC0422s/05: Thu 16:10–18:40 A16/213, J. Slanina
VLBC0422s/06: Thu 16:10–18:40 A16/213, J. Slanina
VLBC0422s/07: Thu 16:10–18:40 A16/213, J. Dostál
VLBC0422s/08: Mon 7:30–10:00 A16/213, H. Paulová
VLBC0422s/09: Mon 10:30–13:00 A16/213, M. Králíková
VLBC0422s/10: Mon 10:30–13:00 A16/213, M. Králíková
VLBC0422s/11: Mon 11:20–13:50 A16/213, J. Tomandl
VLBC0422s/12: Mon 11:20–13:50 A16/213, J. Tomandl
VLBC0422s/13: Mon 7:30–10:00 A16/213, H. Paulová
VLBC0422s/14: Tue 15:00–17:30 A16/213, M. Tomandlová
VLBC0422s/15: Tue 15:00–17:30 A16/213, M. Tomandlová
VLBC0422s/16: Thu 16:10–18:40 A16/213, J. Dostál
VLBC0422s/17: Fri 13:30–16:00 A16/213, E. Táborská
VLBC0422s/18: Fri 13:30–16:00 A16/213, E. Táborská
- Prerequisites (in Czech)
- ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- General Medicine (programme LF, M-VL) (2)
- Course objectives
- Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
- Learning outcomes
- The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
- Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
- Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
- Blood glucose (sources, consumption, regulation). Diabetes mellitus.
- Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
- Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
- The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
- The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
- Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
- Major functions of the kidney. Glomerular filtration.
- Tubular resorption and secretion.
- Neurotransmitters and hormone receptors. The most common signal pathways.
- Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
- Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
- Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
- required literature
- Podklady pro semináře jsou ve studijních materiálech předmětu VSBC041s. The seminar files are available in IS, Study materials VSBC041s.
- Teaching methods
- Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
- Assessment methods
- course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
- Language of instruction
- Further Comments
- The course is taught annually.
- Listed among pre-requisites of other courses
- aVLMO051 Molecular and Cellular Pathophysiology
(aVLFY0422c || aZLFY0422c || VLFY0422c || ZLFY0422c) && (aVLFY0422s || aZLFY0422s || VLFY0422s || ZLFY0422s) && (aVLBC0422c || aZLBC0422c || VLBC0422c || ZLBC0422c) && (aVLBC0422s || aZLBC0422s || VLBC0422s || ZLBC0422s)
- VLLM0522c Medical Microbiology II - practice
VLLM0421c && (VLBC0422c || VSBC041c) && (VLBC0422s || VSBC041s)
- aVLMO051 Molecular and Cellular Pathophysiology
- Teacher's information