VLBI0222p Medical Biology II - lecture

Faculty of Medicine
spring 2021
Extent and Intensity
2/0/0. 3 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: RZk (examination).
Taught online.
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
doc. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
VLBI0121c Biology I -pract.
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering and evolutionary biology
Learning outcomes
After completing the course the student will be able to:
- explain and apply basic principles of human genetics
- explain the role of medical biology in the development of modern therapies (e.g. molecular therapies of cancer)
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome composition
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics, bioinformatics)
  • Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance, Chromosome Abnormalities
  • Introduction to Genetics II – Multifactorial Inheritance, Genetic Linkage, Population Genetics
  • Human Genome and Genomics
  • Epigenetics – Interaction of Genes and Environment
  • Immunogenetics
  • Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
  • Cancer Biology II – Application of Cancer Biology into Cancer Diagnostics and Therapy
  • Bacterial and Viral Genomics
  • Discovering the Structure and Function of Genes
  • Gene Therapy
  • Human Microbiome
  • Stem Cells and Tissue Engineering
  • Evolutionary Biology
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004. xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007. 182 stran. ISBN 9788072624492. info
Teaching methods
lecture every week
Assessment methods
Final exam - oral exam The exam for both Medical Biology I and Medical Biology II - it contains questions based on the topics discussed in the lectures and practices of both semesters.
Language of instruction
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

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Teacher's information
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020.
  • Enrolment Statistics (spring 2021, recent)
  • Permalink: https://is.muni.cz/course/med/spring2021/VLBI0222p