Masaryk University

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    2024

    1. New cyclometalated Ru(ii) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes
      ČERVINKA, Jakub, Alba HERNÁNDEZ-GARCÍA, Delia BAUTISTA, Lenka MARKOVÁ, Hana KOSTRHUNOVÁ, Jaroslav MALINA, Jana KAŠPÁRKOVÁ, M Dolores SANTANA, Viktor BRABEC and José RUIZ. New cyclometalated Ru(ii) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes. INORGANIC CHEMISTRY FRONTIERS. ENGLAND: ROYAL SOC CHEMISTRY, 2024, -, -, p. 1-22. ISSN 2052-1553. Available from: https://dx.doi.org/10.1039/D4QI00732H.
      URL
      RIV: Article in a journal. English. United Kingdom of Great Britain and Northern Ireland.
      Červinka, Jakub (203 Czech Republic, belonging to the institution) -- Hernández-García, Alba (724 Spain) -- Bautista, Delia (724 Spain) -- Marková, Lenka (203 Czech Republic, belonging to the institution) -- Kostrhunová, Hana (203 Czech Republic, belonging to the institution) -- Malina, Jaroslav (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic, belonging to the institution) -- Santana, M Dolores (724 Spain) -- Brabec, Viktor (203 Czech Republic, belonging to the institution) -- Ruiz, José (756 Switzerland)
      Keywords in English: metallodrugs; oncosis; anticancer therapy
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. Jakub Červinka, učo 460361. Changed: 27/5/2024 16:03.
      More: https://is.muni.cz/publication/2405124/en
    2. NEW PHOTOACTIVABLE RUTHENIUM COMPOUND TRIGGERS ONCOSIS IN CANCER CELLS BY DISRUPTING CELLULAR MEMBRANES
      ČERVINKA, Jakub, Lenka MARKOVÁ, Jaroslav MALINA, Jana KAŠPÁRKOVÁ and Viktor BRABEC. NEW PHOTOACTIVABLE RUTHENIUM COMPOUND TRIGGERS ONCOSIS IN CANCER CELLS BY DISRUPTING CELLULAR MEMBRANES. In XXIII. Interdisciplinary meeting of young life scientists. 2024.
      Changed by: Mgr. Jakub Červinka, učo 460361. Changed: 3/6/2024 10:51.
      More: https://is.muni.cz/publication/2407357/en

    2023

    1. N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity
      BRESCIANI, Giulio, Jakub ČERVINKA, Hana KOSTRHUNOVÁ, Lorenzo BIANCALANA, Marco BORTOLUZZI, Guido PAMPALONI, Vojtěch NOVOHRADSKÝ, Viktor BRABEC, Fabio MARCHETTI and Jana KAŠPÁRKOVÁ. N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity. Chemico-Biological Interactions. Elsevier B.V, 2023, vol. 385, November, p. 1-15. ISSN 0009-2797. Available from: https://dx.doi.org/10.1016/j.cbi.2023.110742.
      URL
      RIV/00216224:14310/23:00132046 Article in a journal. English. Ireland.
      Bresciani, Giulio (380 Italy) -- Červinka, Jakub (203 Czech Republic, belonging to the institution) -- Kostrhunová, Hana (203 Czech Republic) -- Biancalana, Lorenzo (380 Italy) -- Bortoluzzi, Marco (380 Italy) -- Pampaloni, Guido (380 Italy) -- Novohradský, Vojtěch (203 Czech Republic) -- Brabec, Viktor (203 Czech Republic) -- Marchetti, Fabio (380 Italy) -- Kašpárková, Jana (203 Czech Republic)
      Keywords in English: Diiron complexes; Indole; Anticancer; Mitochondria; ROS; Antioxidant
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 5/12/2023 11:30.
      More: https://is.muni.cz/publication/2330527/en
    2. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis
      ČERVINKA, Jakub, Alberto GOBBO, Lorenzo BIANCALANA, Lenka MARKOVÁ, Vojtěch NOVOHRADSKÝ, Massimo GUELFI, Stefano ZACCHINI, Jana KAŠPÁRKOVÁ, Viktor BRABEC and Fabio MARCHETTI. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis. In XXII. Interdisciplinary meeting of young life scientists. 2023.
      Changed by: Mgr. Jakub Červinka, učo 460361. Changed: 28/6/2023 10:24.
      More: https://is.muni.cz/publication/2294769/en

    2022

    1. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis
      ČERVINKA, Jakub, Alberto GOBBO, Lorenzo BIANCALANA, Lenka MARKOVÁ, Vojtěch NOVOHRADSKÝ, Massimo GUELFI, Stefano ZACCHINI, Jana KAŠPÁRKOVÁ, Viktor BRABEC and Fabio MARCHETTI. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis. Journal of Medicinal Chemistry. Washington: American Chemical Society, 2022, vol. 65, No 15, p. 10567-10587. ISSN 0022-2623. Available from: https://dx.doi.org/10.1021/acs.jmedchem.2c00722.
      URL
      RIV/00216224:14310/22:00127146 Article in a journal. English. United States of America.
      Červinka, Jakub (203 Czech Republic, belonging to the institution) -- Gobbo, Alberto (380 Italy) -- Biancalana, Lorenzo (380 Italy) -- Marková, Lenka (203 Czech Republic) -- Novohradský, Vojtěch (203 Czech Republic) -- Guelfi, Massimo (380 Italy) -- Zacchini, Stefano (380 Italy) -- Kašpárková, Jana (203 Czech Republic) -- Brabec, Viktor (203 Czech Republic, guarantor) -- Marchetti, Fabio (380 Italy)
      Keywords in English: Metallodrugs; Ruthenium; Anticancer activity; Cell death; Calcium homeostasis
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 8/2/2023 13:38.
      More: https://is.muni.cz/publication/2231719/en

    2012

    1. Platinum-DNA interstrand crosslinks: Molecular determinants of bending and unwinding of the double helix.
      SUCHÁNKOVÁ, Tereza, Karel KUBÍČEK, Jana KAŠPÁRKOVÁ, Viktor BRABEC and Jiří KOZELKA. Platinum-DNA interstrand crosslinks: Molecular determinants of bending and unwinding of the double helix. Journal of Inorganic Biochemistry. New York, USA: Elsevier Science Inc, 2012, vol. 108, No 1, p. 69-79. ISSN 0162-0134. Available from: https://dx.doi.org/10.1016/j.jinorgbio.2011.09.025.
      RIV/00216224:14310/12:00057206 Article in a journal. Biophysics. English. United States of America.
      Suchánková, Tereza (203 Czech Republic) -- Kubíček, Karel (203 Czech Republic, belonging to the institution) -- Kašpárková, Jana (203 Czech Republic) -- Brabec, Viktor (203 Czech Republic, belonging to the institution) -- Kozelka, Jiří (250 France, guarantor, belonging to the institution)
      Keywords in English: Anticancer drugs; Cisplatin; DNA binding; Interstrand crosslinks; Lone pair-pi interactions; Molecular dynamics simulations
      International impact: yes
      Reviewed: yes
      Changed by: Ing. Andrea Mikešková, učo 137293. Changed: 11/4/2013 14:16.
      More: https://is.muni.cz/publication/955330/en

    2009

    1. Energetics, conformation and recognition of DNA duplexes modified by methylated analougues of [PtCl(dien)]+
      NOVÁKOVÁ, Olga, Jaroslav MALINA, Jana KAŠPÁRKOVÁ, Anna HALÁMIKOVÁ, Vladan BERNARD, Francesco INTINI, Giovanni NATILE and Viktor BRABEC. Energetics, conformation and recognition of DNA duplexes modified by methylated analougues of [PtCl(dien)]+. Chemistry – A European Journal. Germany: Wiley, 2009, vol. 2009, No 15, p. 6211-6221. ISSN 0947-6539.
      Biophysics. English. Germany.
      Keywords in English: DNA, DNA recognition, DNA structures, platinum, polymerization
      International impact: yes
      Reviewed: yes
      Changed by: doc. Mgr. Vladan Bernard, Ph.D., učo 60122. Changed: 13/1/2011 11:39.
      More: https://is.muni.cz/publication/842978/en

    2008

    1. Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes
      CASTELLANO-CASTILLO, Maria, Hana KOSTRHUNOVA, María Victoria MARINI PALOMEQUE, Jana KAŠPÁRKOVÁ, Peter J. SADLER, Jean-Marc MALINGE and Viktor BRABEC. Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes. Journal of Biological Inorganic Chemistry. Germany: Springer Berlin / Heidelberg, 2008, vol. 13, No 6, p. 993-999. ISSN 0949-8257.
      Name in Czech: Vazba MutS na nezparovane DNA adukty interkalujicich rutheniovych komplexu
      RIV/00216224:14310/08:00035834 Article in a journal. Biophysics. English. Germany.
      Castellano-Castillo, Maria (724 Spain) -- Kostrhunova, Hana (203 Czech Republic) -- Marini Palomeque, María Victoria (858 Uruguay) -- Kašpárková, Jana (203 Czech Republic) -- Sadler, Peter J. (826 United Kingdom of Great Britain and Northern Ireland) -- Malinge, Jean-Marc (250 France) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: DNA ; Mismatch repair ; MutS ; Ruthenium arene ; Intercalation
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 25/6/2009 12:30.
      More: https://is.muni.cz/publication/837281/en
    2. Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin
      KAŠPÁRKOVÁ, Jana, María Victoria MARINI PALOMEQUE, Vendula BURSOVÁ and Viktor BRABEC. Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin. Biophysical Journal. USA: Biophysical Society, 2008, vol. 95, No 9, p. 4361-4371. ISSN 0006-3495.
      Name in Czech: Biofyzikální analýza stability vnitrořetězcových můstků transplatiny na DNA
      RIV/00216224:14310/08:00035832 Article in a journal. Biophysics. English. United States of America.
      Kašpárková, Jana (203 Czech Republic, guarantor, belonging to the institution) -- Marini Palomeque, María Victoria (858 Uruguay, belonging to the institution) -- Bursová, Vendula (203 Czech Republic, belonging to the institution) -- Brabec, Viktor (203 Czech Republic, belonging to the institution)
      Keywords in English: transplatin; DNA; antitumor
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 17/3/2011 20:46.
      More: https://is.muni.cz/publication/837278/en

    2005

    1. Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)]
      MARINI PALOMEQUE, María Victoria, Petros CHRISTOFIS, Olga NOVÁKOVÁ, Jana KAŠPÁRKOVÁ, Nicholas FARRELL and Viktor BRABEC. Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)]. Nucleic Acids Research. UK: Oxford University Press, 2005, vol. 33, No 18, p. 5819–5828. ISSN 0305-1048.
      Name in Czech: Konformace, rozpoznani proteiny a oprava DNA retezcovych mustku protinadoroveho trans-[PtCl2(NH3)(thiazol)]
      RIV/00216224:14310/05:00028508 Article in a journal. Biophysics. English. United Kingdom of Great Britain and Northern Ireland.
      Marini Palomeque, María Victoria (858 Uruguay) -- Christofis, Petros (300 Greece) -- Nováková, Olga (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Farrell, Nicholas (840 United States of America) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: platinum complexes; DNA; antitumor
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 25/3/2010 13:39.
      More: https://is.muni.cz/publication/837295/en
    2. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.
      NAJAJREH, Yousef, Jana KAŠPÁRKOVÁ, María Victoria MARINI PALOMEQUE, Dan GIBSON and Viktor BRABEC. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand. Journal of Biological Inorganic Chemistry. Germany: Springer Berlin / Heidelberg, 2005, vol. 10, No 7, p. 722-731. ISSN 0949-8257.
      Name in Czech: Strukturni charakterizace a interakce s DNA novych cytotoxickych transplatinovych analogu
      RIV/00216224:14310/05:00035838 Article in a journal. Biophysics. English. Germany.
      Najajreh, Yousef (275 Palestine, State of) -- Kašpárková, Jana (203 Czech Republic) -- Marini Palomeque, María Victoria (858 Uruguay) -- Gibson, Dan (376 Israel) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: Platinum ; DNA ; Cross-links ; Cytotoxicity ; X-ray crystallography
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 25/6/2009 12:38.
      More: https://is.muni.cz/publication/837298/en

    2004

    1. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
      PROKOP, Radim, Jana KAŠPÁRKOVÁ, Olga NOVAKOVA, María Victoria MARINI PALOMEQUE, Ana M. PIZARRO, Carmen NAVARRO-RANNINGER and Viktor BRABEC. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand. Biochemical Pharmacology. Oxford, UK: Elsevier, 2004, vol. 67, No 6, p. 1097-109, 13 pp. ISSN 0006-2952.
      Name in Czech: Interakce novych protinadorovych platinovych komplexu s DNA
      RIV/00216224:14310/04:00029123 Article in a journal. Biophysics. English. United Kingdom of Great Britain and Northern Ireland.
      Prokop, Radim (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Novakova, Olga (203 Czech Republic) -- Marini Palomeque, María Victoria (858 Uruguay) -- Pizarro, Ana M. (724 Spain) -- Navarro-Ranninger, Carmen (724 Spain) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: cisplatin; platinum complexes; DNA; antitumor
      International impact: yes
      Reviewed: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 19/1/2009 14:32.
      More: https://is.muni.cz/publication/792965/en
    2. Vliv ultrazvuku na DNA a na tvorbu komplexu DNA s doxorubicinem
      BEČVÁŘOVÁ, Pavlína, Jiřina ŠKORPÍKOVÁ, Jana KAŠPÁRKOVÁ and Pavel GREC. Vliv ultrazvuku na DNA a na tvorbu komplexu DNA s doxorubicinem. In Sborník XXVII.Dny lékařské biofyziky 2004. Ústav lékařsaké biofyziky LF v Hradci Králové, 2004, p. 2.
      Changed by: doc. RNDr. Jiřina Škorpíková, CSc., učo 413. Changed: 15/10/2004 17:33.
      More: https://is.muni.cz/publication/559122/en

    2003

    1. Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action
      KAŠPÁRKOVÁ, Jana, Olga NOVAKOVÁ, María Victoria MARINI PALOMEQUE, Yousef NAJAJREH, Dan GIBSON, Jose-Manuel PEREZ and Viktor BRABEC. Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2003, vol. 278, No 48, p. 47516-47525. ISSN 0021-9258.
      Name in Czech: Aktivace trans geometrie bifunkcnich mononuklearnich platinovych komplexu piperidinovym ligandem.
      RIV/00216224:14310/03:00029122 Article in a journal. Biophysics. English. United States of America.
      Kašpárková, Jana (203 Czech Republic) -- Novaková, Olga (203 Czech Republic) -- Marini Palomeque, María Victoria (858 Uruguay) -- Najajreh, Yousef (275 Palestine, State of) -- Gibson, Dan (376 Israel) -- Perez, Jose-Manuel (724 Spain) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: cisplatin; platinum complexes; DNA; antitumor
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 15/11/2008 17:39.
      More: https://is.muni.cz/publication/792859/en
    2. DNA Binding Mode of the Cis and Trans Geometries of New Antitumor Nonclassical Platinum Complexes Containing Piperidine, Piperazine, or 4-Picoline Ligand in Cell-Free Media. Relations to Their Activity in Cancer Cell Lines
      KAŠPÁRKOVÁ, Jana, María Victoria MARINI PALOMEQUE, Yousef NAJAJREH, Dan GIBSON and Viktor BRABEC. DNA Binding Mode of the Cis and Trans Geometries of New Antitumor Nonclassical Platinum Complexes Containing Piperidine, Piperazine, or 4-Picoline Ligand in Cell-Free Media. Relations to Their Activity in Cancer Cell Lines. Biochemistry. Washington, USA: American Chemical Society, 2003, vol. 42, No 20, p. 6321 -6332. ISSN 0006-2960.
      Name in Czech: DNA vazba Cis a Trans geometrii novych neklasickych protinadorovych platinovych komplexu obsahujicich piperidin, piperazin nebo 4-pikolin
      RIV/00216224:14310/03:00029121 Article in a journal. Biophysics. English. United States of America.
      Kašpárková, Jana (203 Czech Republic) -- Marini Palomeque, María Victoria (858 Uruguay) -- Najajreh, Yousef (275 Palestine, State of) -- Gibson, Dan (376 Israel) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: platinum complexes; DNA; anticancer
      International impact: yes
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 14/11/2008 18:31.
      More: https://is.muni.cz/publication/792858/en

    2002

    1. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
      MCGREGOR, Tracey D., Alexander HEGMANS, Jana KAŠPÁRKOVÁ, Kamila NEPLECHOVÁ, Olga NOVÁKOVÁ, Hana PEŇÁZOVÁ, Oldřich VRÁNA, Viktor BRABEC and Nicholas FARRELL. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464. Journal of Biological Inorganic Chemistry. Heidelberg: Springer Verlag, 2002, vol. 2002, No 7, p. 397-404, 7 pp. ISSN 0949-8257.
      URL
      Name (in English): A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
      RIV/00216224:14310/02:00007654 Article in a journal. Biophysics. English. Germany.
      McGregor, Tracey D. (840 United States of America) -- Hegmans, Alexander (276 Germany) -- Kašpárková, Jana (203 Czech Republic) -- Neplechová, Kamila (203 Czech Republic) -- Nováková, Olga (203 Czech Republic) -- Peňázová, Hana (203 Czech Republic) -- Vrána, Oldřich (203 Czech Republic) -- Brabec, Viktor (203 Czech Republic, guarantor) -- Farrell, Nicholas (840 United States of America)
      Keywords in English: unwinding; dinuclear platinum; hydrogen bonding; cross-links
      Changed by: doc. Mgr. Hana Cídlová, Dr., učo 761. Changed: 30/11/2006 12:01.
      More: https://is.muni.cz/publication/485468/en
    2. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium
      MARINI, Victoria, Jana KAŠPÁRKOVÁ, Olga NOVAKOVA, Luigi MONSU SCOLARO, Raffaello ROMEO and Viktor BRABEC. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium. Journal of Biological Inorganic Chemistry. 2002, vol. 7, No 7, p. 725-734. ISSN 0949-8257.
      URL
      Name in Czech: Biofyzikální analýza dvouřetězcová DNA modifikována dinukleární platinovou organometalovou sloučeninou
      RIV/00216224:14310/02:00028886 Article in a journal. Biophysics. English. Germany.
      Marini, Victoria (858 Uruguay) -- Kašpárková, Jana (203 Czech Republic) -- Novakova, Olga (203 Czech Republic) -- Monsu Scolaro, Luigi (380 Italy) -- Romeo, Raffaello (380 Italy) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: DNA;Organoplatinum(II);Adducts;Cross-link;Conformation
      Changed by: Mgr. María Victoria Marini Palomeque, Ph.D., učo 22912. Changed: 20/6/2009 16:08.
      More: https://is.muni.cz/publication/406361/en

    2001

    1. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464
      ZEHNULOVÁ, Jana, Jana KAŠPÁRKOVÁ, Nicholas FARRELL and Viktor BRABEC. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol., 2001, vol. 276, No 25, p. 22191-22199. ISSN 0021-9258.
      RIV/00216224:14310/01:00004290 Article in a journal. Biophysics. English. Czech Republic.
      Keywords in English: DNA; anticancer drug; platinum; conformation; recognition
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 2/7/2001 12:08.
      More: https://is.muni.cz/publication/365796/en
    2. Different recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53
      KAŠPÁRKOVÁ, Jana, Šárka POSPÍŠILOVÁ and Viktor BRABEC. Different recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol., 2001, vol. 276, No 19, p. 16064-16069. ISSN 0021-9258.
      RIV/00216224:14310/01:00004213 Article in a journal. Biophysics. English. Czech Republic.
      Keywords in English: DNA; p53; protinádorová aktivita; interakce; cisplatina
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 25/5/2001 15:16.
      More: https://is.muni.cz/publication/362474/en
    3. Differential recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53
      KAŠPÁRKOVÁ, Jana, Šárka POSPÍŠILOVÁ and Viktor BRABEC. Differential recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53. In Journal of Biological Chemistry. 2001, p. 16064-16069.

      Keywords in English: DNA; p53; cisplatina; cytostatika; mechanismus
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 25/5/2001 14:39.
      More: https://is.muni.cz/publication/362473/en

    2000

    1. A comparison of DNA binding profiles of bis platinum compounds with polyamine linkers and a trinuclear platinum phase I clinical agent
      MCGREGOR, Tracey Dawn, Jana KASPARKOVA, Olga NOVAKOVA and Hana PENAZOVA. A comparison of DNA binding profiles of bis platinum compounds with polyamine linkers and a trinuclear platinum phase I clinical agent. In VRANA, Oldrich, Viktor BRABEC and Nicholas FARRELL. Proceedings of the American Association for Cancer Research. San Francicso, CA, USA: American Association for Cancer Research, 2000, p. 264.
      Name (in English): A comparison of DNA binding profiles of bis platinum compounds with polyamine linkers and a trinuclear platinum phase I clinical agent
      RIV/00216224:14410/00:00003374 Proceedings paper. Biophysics. English. United States of America.
      Changed by: doc. Mgr. Hana Cídlová, Dr., učo 761. Changed: 25/1/2001 07:05.
      More: https://is.muni.cz/publication/341191/en
    2. Antitumor efficient platinum complexes with trans-geometry and their reactions with DNA
      NEPLECHOVÁ, Kamila, Jana KAŠPÁRKOVÁ, Radim PROKOP, Nicholas FARRELL and Viktor BRABEC. Antitumor efficient platinum complexes with trans-geometry and their reactions with DNA. In Program and Abstracts. Brno: BFÚ Brno, 2000, p. 111.
      RIV/00216224:14310/00:00007660 Proceedings paper. Biophysics. English. Czech Republic.
      Neplechová, Kamila (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Prokop, Radim (203 Czech Republic) -- Farrell, Nicholas (840 United States of America) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: DNA binding; platinum complexes
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 21/5/2003 17:18.
      More: https://is.muni.cz/publication/485622/en
    3. Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes
      KAŠPÁRKOVÁ, Jana, Nicholas FARRELL and Viktor BRABEC. Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2000, vol. 275, No 21, p. 15789-15799. ISSN 0021-9258.
      RIV/00216224:14310/00:00003308 Article in a journal. Biophysics. English. Czech Republic.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 27/2/2001 09:57.
      More: https://is.muni.cz/publication/328491/en
    4. Steric control of DNA interstrand cross-link sites of antitumor trans-platinum complexes
      NEPLECHOVÁ, Kamila, Jana KAŠPÁRKOVÁ, Nicholas FARRELL and Viktor BRABEC. Steric control of DNA interstrand cross-link sites of antitumor trans-platinum complexes. In 34th ICCC, Abstracts, Oral Presentations. Edinburgh, GB: Royal Chemical Society, 2000, p. 1173.
      RIV/00216224:14310/00:00007659 Proceedings paper. Biophysics. English. United Kingdom of Great Britain and Northern Ireland.
      Neplechová, Kamila (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Farrell, Nicholas (840 United States of America) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: DNA; platinum; cross-link
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 21/5/2003 17:30.
      More: https://is.muni.cz/publication/485621/en
    5. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups
      BRABEC, Viktor, Kamila NEPLECHOVÁ, Jana KAŠPÁRKOVÁ and Nicholas FARRELL. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups. Journal of Biological Inorganic Chemistry. Germany: Springer-Verlag, 2000, vol. 2000, No 5, p. 364-368. ISSN 0949-8257.
      RIV/00216224:14310/00:00003310 Article in a journal. Biophysics. English. Czech Republic.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 27/2/2001 10:02.
      More: https://is.muni.cz/publication/328911/en
    6. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonlelaving groups
      BRABEC, Viktor, Kamila NEPLECHOVÁ, Jana KAŠPÁRKOVÁ and Nicholas FARRELL. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonlelaving groups. Journal of Biological Inorganic Chemistry. Heidelberg: Springer Verlag, 2000, vol. 2000, 5/3, p. 364-368. ISSN 0949-8257.
      URL
      RIV/00216224:14310/00:00007652 Article in a journal. Biophysics. English. Germany.
      Brabec, Viktor (203 Czech Republic, guarantor) -- Neplechová, Kamila (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Farrell, Nicholas (840 United States of America)
      Keywords in English: DNA;cisplatin; transplatin; cross-link; dimethyl sulfate
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 21/5/2003 16:57.
      More: https://is.muni.cz/publication/485464/en

    1999

    1. DNA Interactions of New Antitumor Aminophosphine Platinum (II) Complexes
      NEPLECHOVÁ, Kamila, Jana KAŠPÁRKOVÁ, Oldřich VRÁNA, Olga NOVÁKOVÁ, Abraha HABTEMARIAM, Beth WATCHMAN, Peter J. SADLER and Viktor BRABEC. DNA Interactions of New Antitumor Aminophosphine Platinum (II) Complexes. Molecular Pharmacology. USA: ASPET, 1999, vol. 1999, No 56, p. 20-30. ISSN 1521-01.
      URL
      Name (in English): DNA Interactions of New Antitumor Aminophosphine Platinum (II) Complexes
      RIV/00216224:14310/99:00007653 Article in a journal. Biophysics. English. United States of America.
      Neplechová, Kamila (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Vrána, Oldřich (203 Czech Republic) -- Nováková, Olga (203 Czech Republic) -- Habtemariam, Abraha (826 United Kingdom of Great Britain and Northern Ireland) -- Watchman, Beth (826 United Kingdom of Great Britain and Northern Ireland) -- Sadler, Peter J. (826 United Kingdom of Great Britain and Northern Ireland) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: DNA; platinum complexes; modification; biophysical analysis
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 21/5/2003 16:51.
      More: https://is.muni.cz/publication/485465/en
    2. DNA interactions of new antitumor aminophosphine platinum(II) complexes
      NEPLECHOVÁ, Kamila, Jana KAŠPÁRKOVÁ, Oldřich VRÁNA, Olga NOVÁKOVÁ, Abraha HABTEMARIAM, Beth WATCHMAN, Peter SADLER and Viktor BRABEC. DNA interactions of new antitumor aminophosphine platinum(II) complexes. Molecular Pharmacology. Baltimore, USA: Williams and Wilkins, 1999, No 56, p. 20-30. ISSN 0026-895X.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 6/9/2000 07:38.
      More: https://is.muni.cz/publication/329055/en
    3. DNA modifications by a novel bifunctional trinuclear platinum Phase I anticancer agent
      BRABEC, Viktor, Jana KAŠPÁRKOVÁ, Oldřich VRÁNA, Olga NOVÁKOVÁ, John W. COX, Yun QU and Nicholas FARRELL. DNA modifications by a novel bifunctional trinuclear platinum Phase I anticancer agent. Biochemistry. Washington, USA: American Chemical Society, 1999, No 38, p. 6781-6790. ISSN 0006-2960.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 6/9/2000 07:39.
      More: https://is.muni.cz/publication/329052/en
    4. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking
      KAŠPÁRKOVÁ, Jana, Olga NOVÁKOVÁ, Oldřich VRÁNA, Nicholas FARRELL and Viktor BRABEC. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking. Biochemistry. Washington, USA: American Chemical Society, 1999, No 38, p. 10997-11010. ISSN 0006-2960.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 6/9/2000 07:39.
      More: https://is.muni.cz/publication/329054/en

    1998

    1. DNA Interactions of a Novel Drug, cis[PtCl(NH3)2(N7 - Acyklovir)]+
      BALCAROVÁ, Zdeňka, Jana KAŠPÁRKOVÁ, Alena ŽÁKOVSKÁ, Olga NOVÁKOVÁ, maria SIVO, Giovanni NATILE and Viktor BRABEC. DNA Interactions of a Novel Drug, cis[PtCl(NH3)2(N7 - Acyklovir)]+. Molecular Pharmacology. American Society for Pharmacology, 1998, vol. 53, No 1998, p. 446-456. ISSN 0026-895X.
      Name (in English): DNA Interactions of a Novel Drug, cis[PtCl(NH3)2(N7 - Acyklovir)]+
      Oncology and haematology. English. United States of America.
      Keywords in English: ACV; acyclovir
      Changed by: doc. RNDr. Alena Žákovská, Ph.D., učo 417. Changed: 27/5/2003 08:44.
      More: https://is.muni.cz/publication/220512/en
    2. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)(2)(N7-acyclovir)]
      BALCAROVÁ, Zdeňka, Jana KAŠPÁRKOVÁ, Alena ŽÁKOVSKÁ, Olga NOVÁKOVÁ, Maria F. SIVO, Giovanni NATILE and Viktor BRABEC. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)(2)(N7-acyclovir)]. MOLECULAR PHARMACOLOGY. 1998, vol. 53, No 5, 10 pp. ISSN 0026-895X.
      RIV: Article in a journal. Pharmacology and apothecary chemistry. English. United States of America.
      Balcarová, Zdeňka (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Žákovská, Alena (203 Czech Republic) -- Nováková, Olga (203 Czech Republic) -- Sivo, Maria F. (380 Italy) -- Natile, Giovanni (380 Italy) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: INTERSTRAND CROSS-LINKS; ANTITUMOR AGENTS; CELL-DEATH; COMPLEXES; CIS-DIAMMINEDICHLOROPLATINUM(II); ADDUCTS; FLUORESCENCE; CISPLATIN; TRANS-DIAMMINEDICHLOROPLATINUM(II); APOPTOSIS
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 5/8/2010 14:00.
      More: https://is.muni.cz/publication/893200/en
    3. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)2(N7-acyclovir)]+
      BALCAROVÁ, Zdeňka, Jana KAŠPÁRKOVÁ, Alena ŽÁKOVSKÁ, Olga NOVÁKOVÁ, Maria F. SIVO, Giovanni NATILE and Viktor BRABEC. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)2(N7-acyclovir)]+. Molecular Pharmacology. Baltimore, USA: Williams and Wilkins, 1998, No 53, p. 846-855. ISSN 0026-895X.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 7/9/2000 08:10.
      More: https://is.muni.cz/publication/329731/en

    1997

    1. DNA binding of properties of trinuclear platinum complex
      QU, Yun, Nicholas FARRELL, Jana KAŠPÁRKOVÁ and Viktor BRABEC. DNA binding of properties of trinuclear platinum complex. Journal of Inorganic Biochemistry. New York: Elsevier, 1997, No 67, p. 174. ISSN 0162-0134.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 7/9/2000 08:24.
      More: https://is.muni.cz/publication/329792/en
    2. DNA interaction of bifunctional dinuclear platinum (II) antitumor agents.
      ŽALUDOVÁ, Renata, Alena ŽÁKOVSKÁ, J. KAŠPÁRKOVÁ, Z. BALCAROVÁ and O. VRÁNA. DNA interaction of bifunctional dinuclear platinum (II) antitumor agents. European Journal of Biochemistry. Oxford: Blackwell Science, 1997, vol. 647, No 1, p. 1-10. ISSN 0014-2956.
      Name (in English): DNA interaction of bifunctional dinuclear platinum (II) antitumor agents.
      Physiology. English. Czech Republic.
      Keywords in English: DNA; platinum componds
      Changed by: doc. RNDr. Alena Žákovská, Ph.D., učo 417. Changed: 28/5/2003 14:00.
      More: https://is.muni.cz/publication/198099/en
    3. DNA interactions of bifunctional dinuclear platinum(II) antitumor agents
      ŽALUDOVÁ, Renata, Alena ŽÁKOVSKÁ, Jana KAŠPÁRKOVÁ, Zdeňka BALCAROVÁ, Vladimír KLEINWÄCHTER, Oldřich VRÁNA, Nicholas FARRELL and Viktor BRABEC. DNA interactions of bifunctional dinuclear platinum(II) antitumor agents. EUROPEAN JOURNAL OF BIOCHEMISTRY. 1997, vol. 246, No 2, 10 pp. ISSN 0014-2956.
      RIV: Article in a journal. Biochemistry. English. United States of America.
      Žaludová, Renata (203 Czech Republic) -- Žákovská, Alena (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Balcarová, Zdeňka (203 Czech Republic) -- Kleinwächter, Vladimír (203 Czech Republic) -- Vrána, Oldřich (203 Czech Republic) -- Farrell, Nicholas (840 United States of America, guarantor) -- Brabec, Viktor (203 Czech Republic)
      Keywords in English: DNA; platinum drug; dinuclear complex; cross-link; anticancer effect
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 5/8/2010 14:29.
      More: https://is.muni.cz/publication/893205/en
    4. DNA interactions of bifunctional dinuclear platinum(II) antitumor agents
      ŽALUDOVÁ, Renata, Alena ŽÁKOVSKÁ, Jana KAŠPÁRKOVÁ, Zdeňka BALCAROVÁ, Vladimír KLEINWÄCHTER, Oldřich VRÁNA, Nicholas FARRELL and Viktor BRABEC. DNA interactions of bifunctional dinuclear platinum(II) antitumor agents. European Journal of Biochemistry. New York, USA: Springer, 1997, No 246, p. 508-517. ISSN 0014-2956.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 7/9/2000 08:39.
      More: https://is.muni.cz/publication/329832/en
    5. DNA modifications by antitumor trans-[PtCl2(E-iminoether)(2)]
      ŽALUDOVÁ, Renata, Alena ŽÁKOVSKÁ, Jana KAŠPÁRKOVÁ, Zdeňka BALCAROVÁ, Oldřich VRÁNA, Mauro COLUCCIA, Giovanni NATILE and Viktor BRABEC. DNA modifications by antitumor trans-[PtCl2(E-iminoether)(2)]. MOLECULAR PHARMACOLOGY. 1997, vol. 52, No 3, 8 pp. ISSN 0026-895X.
      RIV: Article in a journal. Pharmacology and apothecary chemistry. English. United States of America.
      Žaludová, Renata (203 Czech Republic) -- Žákovská, Alena (203 Czech Republic) -- Kašpárková, Jana (203 Czech Republic) -- Balcarová, Zdeňka (203 Czech Republic) -- Vrána, Oldřich (203 Czech Republic) -- Coluccia, Mauro (380 Italy) -- Natile, Giovanni (380 Italy) -- Brabec, Viktor (203 Czech Republic, guarantor)
      Keywords in English: INTERSTRAND CROSS-LINKS; ANTI-TUMOR ACTIVITY; PLATINUM COMPLEXES; IN-VITRO; CISPLATIN; BINDING; CIS-DIAMMINEDICHLOROPLATINUM(II); ADDUCTS; CYTOTOXICITY; ANTIBODIES
      Changed by: RNDr. Kamila Neplechová, Ph.D., učo 70207. Changed: 5/8/2010 14:14.
      More: https://is.muni.cz/publication/893203/en
    6. DNA modifications by antitumor trans-[PtCl2(E-iminoether)2]
      ŽALUDOVÁ, Renata, Alena ŽÁKOVSKÁ, Jana KAŠPÁRKOVÁ, Zdeňka BALCAROVÁ, Oldřich VRÁNA, Mauro COLUCCIA, Giovanni NATILE and Viktor BRABEC. DNA modifications by antitumor trans-[PtCl2(E-iminoether)2]. Molecular Pharmacology. Baltimore, USA: Williams and Wilkins, 1997, No 52, p. 354-361. ISSN 0026-895X.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 7/9/2000 08:43.
      More: https://is.muni.cz/publication/329853/en
    7. DNA modifications by tumor trans - [PtCl2 (E-iminoether)2].
      ŽALUDOVÁ, R., Alena ŽÁKOVSKÁ, J. KAŠPÁRKOVÁ, Z. BALCAROVÁ and O. VRÁNA. DNA modifications by tumor trans - [PtCl2 (E-iminoether)2]. Molecular Pharmacology. American Society for Pharmacology, 1997, vol. 52, No 1, p. 354-361. ISSN 0026-895X.
      Name (in English): DNA modifications by tumor trans - [PtCl2 (E-iminoether)2].
      Physiology. English. Czech Republic.
      Keywords in English: platinum; phamacology
      Changed by: doc. RNDr. Alena Žákovská, Ph.D., učo 417. Changed: 28/5/2003 14:03.
      More: https://is.muni.cz/publication/198100/en

    1996

    1. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies
      KAŠPÁRKOVÁ, Jana, K.J. MELISH, Yun QU, Viktor BRABEC and Nicholas FARRELL. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies. Biochemistry. Washington, DC, USA: American Chemical Society, 1996, No 35, p. 16705-16713. ISSN 0006-2960.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 8/9/2000 08:54.
      More: https://is.muni.cz/publication/330251/en

    1995

    1. Correlation between cytotoxicity and DNA binding of polypyridyl ruthenium complexes
      NOVÁKOVÁ, Olga, Jana KAŠPÁRKOVÁ, Oldřich VRÁNA, Paul M. VANVLIET, Jan REEDIJK and Viktor BRABEC. Correlation between cytotoxicity and DNA binding of polypyridyl ruthenium complexes. Biochemistry. Washington, DC, USA: American Chemical Society, 1995, No 34, p. 12369-12378. ISSN 0006-2960.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 10/9/2000 14:00.
      More: https://is.muni.cz/publication/330452/en
    2. Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA- binding proteins
      KAŠPÁRKOVÁ, Jana and Viktor BRABEC. Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA- binding proteins. Biochemistry. Washington, DC, USA: American Chemical Society, 1995, No 34, p. 12379-12387. ISSN 0006-2960.
      Changed by: prof. RNDr. Viktor Brabec, DrSc., učo 46787. Changed: 10/9/2000 13:57.
      More: https://is.muni.cz/publication/330451/en
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