aVLBC0422s Biochemie II - seminář

Lékařská fakulta
jaro 2025
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
doc. RNDr. Jiří Dostál, CSc. (cvičící)
prof. RNDr. Eva Táborská, CSc. (cvičící)
doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
Mgr. Jana Gregorová, Ph.D. (pomocník)
MUDr. Michaela Králíková, Ph.D. (pomocník)
RNDr. Hana Paulová, CSc. (pomocník)
doc. Mgr. Ondřej Peš, Ph.D. (pomocník)
Mgr. Jiří Slanina, Ph.D. (pomocník)
Mgr. Marie Tomandlová, Ph.D. (pomocník)
Garance
doc. RNDr. Josef Tomandl, Ph.D.
Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: MUDr. Michaela Králíková, Ph.D.
Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Předpoklady
aVLBC0321s Biochemistry I - seminar && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Seminars are complementary to the course Biochemistry II - lecture. The aim of the course is to practise (i) the basic principles of intermediary metabolism and its regulation in various states of the organism at all levels, (ii) the characteristic features of metabolism of individual organs and tissues, (iii) the principles of maintaining homeostasis of the organism, including acid-base balance.
Výstupy z učení
The student will be able:
- to explain the interrelationship between the metabolism of nutrients under different states of the organism.
- to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
- to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modelling situations
- to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
- to explain the principles of metabolism regulation at all levels.
Osnova
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry. Analysers, POCT.
  • Blood glucose. Protein metabolism. Proteins in nutrition. Transport forms of ammonia.
  • Lipoproteins and their metabolism. Cholesterol transport and balance.
  • Relationships between major metabolic pathways of essential nutrients in various states. Malnutrition. Obesity. Metabolic syndrome. Metabolism during stress.
  • Liver functions, role in nutrient metabolism. Heme catabolism, hyperbilirubinemia. Role of liver in metabolism of hormones and vitamins. Metabolism of Fe.
  • Biotransformation of xenobiotics. Metabolism of ethanol.
  • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volemia.
  • Acid-base balance, parameters, regulation, disorders. Buffer bases. Transport of O2 a CO2.
  • Major functions of kidneys. Glomerular filtration. Tubular resorption and secretion.
  • Neurotransmitters and hormone receptors. The most common signal pathways.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle work. Effect of NO. Energetics of muscle work.
  • Metabolism of Ca, Mg, P, F, I.
  • Extracellular matrix. Metabolism of connective tissue and skin, bone biomarkers.
Literatura
    povinná literatura
  • Study materials for the course in IS MU.
  • RODWELL, Victor W., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY a P. Anthony WEIL. Harper's illustrated biochemistry. Thirty-first edition. New York: McGraw-Hill, 2018, x, 789. ISBN 9781260288421. info
    doporučená literatura
  • LIEBERMAN, Michael, Allan D. MARKS a Alisa PEET. Marks' basic medical biochemistry : a clinical approach. Illustrated by Matthew Chansky. 4th ed. Baltimore: Lippincott, Williams & Wilkins, 2013, ix, 1014. ISBN 9781451100037. info
  • Recommended literature from medical physiology in the course aVLFY0422p.
Výukové metody
Seminary course. Class discussions on assigned topics.
Metody hodnocení
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Failure to meet the requirements of in-term tests requires a resit test, which may be repeated only once.
Detailed conditions are published in Study materials posted under the course/Interactive Syllabus.
Vyučovací jazyk
Angličtina
Informace učitele
Information about seminars, the conditions for giving the course-unit credit, and the syllabus are available in the IS MU in the course-related instructions.
Consultations are possible after a personal arrangement with the teacher.
Další komentáře
Předmět je vyučován každoročně.
Výuka probíhá každý týden.
Successful completion of the course is a condition for access to the exam in the course aVLBC0422p.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024.

aVLBC0422s Biochemie II - seminář

Lékařská fakulta
jaro 2024
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučující
doc. RNDr. Jiří Dostál, CSc. (cvičící)
prof. RNDr. Eva Táborská, CSc. (cvičící)
doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
Mgr. Jana Gregorová, Ph.D. (pomocník)
MUDr. Michaela Králíková, Ph.D. (pomocník)
RNDr. Hana Paulová, CSc. (pomocník)
doc. Mgr. Ondřej Peš, Ph.D. (pomocník)
Mgr. Jiří Slanina, Ph.D. (pomocník)
Mgr. Marie Tomandlová, Ph.D. (pomocník)
Garance
doc. RNDr. Josef Tomandl, Ph.D.
Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: MUDr. Michaela Králíková, Ph.D.
Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLBC0422s/30: St 11:00–13:50 A16/215, J. Tomandl
aVLBC0422s/31: Čt 22. 2. až Čt 9. 5. Čt 14:00–16:50 A16/213, Čt 23. 5. až Čt 30. 5. Čt 14:00–16:50 A16/213, J. Tomandl
aVLBC0422s/32: Čt 22. 2. až Čt 9. 5. Čt 11:00–13:50 A16/213, Čt 23. 5. až Čt 30. 5. Čt 11:00–13:50 A16/213, J. Tomandl
aVLBC0422s/33: Čt 22. 2. až Čt 9. 5. Čt 11:00–13:50 A16/213, Čt 23. 5. až Čt 30. 5. Čt 11:00–13:50 A16/213, J. Tomandl
aVLBC0422s/34: Út 14:00–16:50 A16/215, J. Dostál
aVLBC0422s/35: Po 8:00–10:50 A16/213, E. Táborská
aVLBC0422s/36: Po 8:00–10:50 A16/213, E. Táborská
aVLBC0422s/37: St 11:00–13:50 A16/215, J. Tomandl
aVLBC0422s/38: Út 14:00–16:50 A16/215, J. Dostál
aVLBC0422s/39: Čt 22. 2. až Čt 9. 5. Čt 14:00–16:50 A16/213, Čt 23. 5. až Čt 30. 5. Čt 14:00–16:50 A16/213, J. Tomandl
Předpoklady
aVLBC0321s Biochemistry I - seminar && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Seminars are complementary to the course Biochemistry II - lecture. The aim of the course is to practise (i) the basic principles of intermediary metabolism and its regulation in various states of the organism at all levels, (ii) the characteristic features of metabolism of individual organs and tissues, (iii) the principles of maintaining homeostasis of the organism, including acid-base balance.
Výstupy z učení
The student will be able:
- to explain the interrelationship between the metabolism of nutrients under different states of the organism.
- to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
- to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modelling situations
- to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
- to explain the principles of metabolism regulation at all levels.
Osnova
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry. Analysers, POCT.
  • Blood glucose. Protein metabolism. Proteins in nutrition. Transport forms of ammonia.
  • Lipoproteins and their metabolism. Cholesterol transport and balance.
  • Relationships between major metabolic pathways of essential nutrients in various states. Malnutrition. Obesity. Metabolic syndrome. Metabolism during stress.
  • Liver functions, role in nutrient metabolism. Heme catabolism, hyperbilirubinemia. Role of liver in metabolism of hormones and vitamins. Metabolism of Fe.
  • Biotransformation of xenobiotics. Metabolism of ethanol.
  • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volemia.
  • Acid-base balance, parameters, regulation, disorders. Buffer bases. Transport of O2 a CO2.
  • Major functions of kidneys. Glomerular filtration. Tubular resorption and secretion.
  • Neurotransmitters and hormone receptors. The most common signal pathways.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle work. Effect of NO. Energetics of muscle work.
  • Metabolism of Ca, Mg, P, F, I.
  • Extracellular matrix. Metabolism of connective tissue and skin, bone biomarkers.
Literatura
    povinná literatura
  • Study materials for the course Biochemistry II in IS MUNI.
  • RODWELL, Victor W., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY a P. Anthony WEIL. Harper's illustrated biochemistry. Thirty-first edition. New York: McGraw-Hill, 2018, x, 789. ISBN 9781260288421. info
    doporučená literatura
  • LIEBERMAN, Michael, Allan D. MARKS a Alisa PEET. Marks' basic medical biochemistry : a clinical approach. Illustrated by Matthew Chansky. 4th ed. Baltimore: Lippincott, Williams & Wilkins, 2013, ix, 1014. ISBN 9781451100037. info
  • Recommended literature from medical physiology in the course aVLFY0422p.
Výukové metody
Seminary course. Class discussions on assigned topics.
Metody hodnocení
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Failure to meet the requirements of in-term tests requires a resit test, which may be repeated only once. All absences must be made up before a resit test.
Detailed conditions are published in Study materials posted under the course/Interactive Syllabus.
Vyučovací jazyk
Angličtina
Informace učitele
https://is.muni.cz/auth/el/1411/jaro2024/aVLBC0422s/
Information about seminars, the conditions for giving the course-unit credit, and the syllabus are available in the IS MUNI in the course-related instructions.
Consultations are possible after a personal arrangement with the teacher.
Další komentáře
Předmět je vyučován každoročně.
Successful completion of the course is a condition for access to the exam in the course aVLBC0422p.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2025.

aVLBC0422s Biochemie II - seminář

Lékařská fakulta
jaro 2023
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučující
doc. RNDr. Jiří Dostál, CSc. (cvičící)
RNDr. Hana Paulová, CSc. (cvičící)
prof. RNDr. Eva Táborská, CSc. (cvičící)
doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
Mgr. Jana Gregorová, Ph.D. (pomocník)
MUDr. Michaela Králíková, Ph.D. (pomocník)
doc. Mgr. Ondřej Peš, Ph.D. (pomocník)
Mgr. Jiří Slanina, Ph.D. (pomocník)
Mgr. Jindra Smutná, Ph.D. (pomocník)
Bc. Ivana Ševčíková (pomocník)
Mgr. Marie Tomandlová, Ph.D. (pomocník)
Garance
doc. RNDr. Josef Tomandl, Ph.D.
Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: RNDr. Hana Paulová, CSc.
Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLBC0422s/30: Po 13. 2. až Čt 4. 5. Čt 12:00–14:30 A16/215; a Čt 18. 5. 12:00–14:30 A16/215, Čt 25. 5. 12:00–14:30 A16/215, J. Tomandl
aVLBC0422s/31: St 11:00–13:30 A16/215, J. Dostál
aVLBC0422s/32: St 11:00–13:30 A16/213, E. Táborská
aVLBC0422s/33: St 11:00–13:30 A16/213, E. Táborská
aVLBC0422s/34: Po 8:00–10:30 A16/213, E. Táborská
aVLBC0422s/35: Po 13. 2. až Čt 4. 5. Čt 12:00–14:30 A16/215; a Čt 18. 5. 12:00–14:30 A16/215, Čt 25. 5. 12:00–14:30 A16/215, J. Tomandl
aVLBC0422s/36: St 11:00–13:30 A16/215, J. Dostál
aVLBC0422s/37: Po 13. 2. až Čt 4. 5. Čt 15:00–17:30 A16/215; a Čt 18. 5. 15:00–17:30 A16/215, Čt 25. 5. 15:00–17:30 A16/215, J. Tomandl
aVLBC0422s/38: Po 8:00–10:30 A16/213, E. Táborská
aVLBC0422s/39: Po 13. 2. až Čt 4. 5. Čt 15:00–17:30 A16/215; a Čt 18. 5. 15:00–17:30 A16/215, Čt 25. 5. 15:00–17:30 A16/215, J. Tomandl
Předpoklady
aVLBC0321s Biochemie I - seminář && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Seminars are complementary to the course Biochemistry II - lecture. The aim of the course is to practise (i) the basic principles of intermediary metabolism and its regulation in various states of the organism at all levels, (ii) the characteristic features of metabolism of individual organs and tissues, (iii) the principles of maintaining homeostasis of the organism, including acid-base balance.
Výstupy z učení
The student will be able:
- to explain the interrelationship between the metabolism of nutrients under different states of the organism.
- to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
- to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modelling situations
- to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
- to explain the principles of metabolism regulation at all levels.
Osnova
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry. Analysers, POCT.
  • Blood glucose. Protein metabolism. Proteins in nutrition. Transport forms of ammonia.
  • Lipoproteins and their metabolism. Cholesterol transport and balance.
  • Relationships between major metabolic pathways of essential nutrients in various states. Malnutrition. Obesity. Metabolic syndrome. Metabolism during stress.
  • Liver functions, role in nutrient metabolism. Heme catabolism, hyperbilirubinemia. Role of liver in metabolism of hormones and vitamins. Metabolism of Fe.
  • Biotransformation of xenobiotics. Metabolism of ethanol.
  • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volemia.
  • Acid-base balance, parameters, regulation, disorders. Buffer bases. Transport of O2 a CO2.
  • Major functions of kidneys. Glomerular filtration. Tubular resorption and secretion.
  • Neurotransmitters and hormone receptors. The most common signal pathways.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle work. Effect of NO. Energetics of muscle work.
  • Metabolism of Ca, Mg, P, F, I.
  • Extracellular matrix. Metabolism of connective tissue and skin, bone biomarkers.
Literatura
    povinná literatura
  • Study materials for the course Biochemistry II in IS MUNI.
  • RODWELL, Victor W., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY a P. Anthony WEIL. Harper's illustrated biochemistry. Thirty-first edition. New York: McGraw-Hill, 2018, x, 789. ISBN 9781260288421. info
    doporučená literatura
  • LIEBERMAN, Michael, Allan D. MARKS a Alisa PEET. Marks' basic medical biochemistry : a clinical approach. Illustrated by Matthew Chansky. 4th ed. Baltimore: Lippincott, Williams & Wilkins, 2013, ix, 1014. ISBN 9781451100037. info
  • Recommended literature from medical physiology in the course aVLFY0422p.
Výukové metody
Seminary course. Class discussions on assigned topics.
Metody hodnocení
Course-unit credit.
Conditions for giving the course-unit credit (all conditions should be met):
  • completion of all lessons, missed lessons must be made up,
  • minimal success rate of 70 % from the sum of all revision tests or minimal success rate of 50 % from the credit test. The resit credit test can be taken only once.
    The detailed conditions are posted in IS MUNI (Study materials – Course-related instructions).
    • Vyučovací jazyk
    Angličtina
    Informace učitele
    Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MUNI in the Course-related instructions. The syllabus is also posted on the notice board of the Department of Biochemistry.
    Consultations are possible after a personal arrangement with the teacher.
    Další komentáře
    Předmět je vyučován každoročně.
    Successful completion of the course is a condition for access to the exam in the course aVLBC0422p.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2020, jaro 2021, jaro 2022, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2022
    Rozsah
    0/3/0. 45. 3 kr. Ukončení: z.
    Vyučující
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    MUDr. Michaela Králíková, Ph.D. (pomocník)
    RNDr. Hana Paulová, CSc. (pomocník)
    Mgr. Jiří Slanina, Ph.D. (pomocník)
    Bc. Ivana Ševčíková (pomocník)
    Mgr. Marie Tomandlová, Ph.D. (pomocník)
    Garance
    doc. RNDr. Josef Tomandl, Ph.D.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Kontaktní osoba: prof. RNDr. Eva Táborská, CSc.
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/28: St 11:00–13:30 A16/215, J. Tomandl
    aVLBC0422s/29: St 11:00–13:30 A16/215, J. Tomandl
    aVLBC0422s/30: St 11:00–13:30 A16/213, E. Táborská
    aVLBC0422s/31: St 11:00–13:30 A16/213, E. Táborská
    aVLBC0422s/32: Čt 12:00–14:30 A16/215, J. Tomandl
    aVLBC0422s/33: Čt 12:00–14:30 A16/215, J. Tomandl
    aVLBC0422s/34: Po 11:00–13:30 A16/213, J. Dostál
    aVLBC0422s/35: Po 11:00–13:30 A16/213, J. Dostál
    aVLBC0422s/36: St 16:00–18:30 A16/213, E. Táborská
    aVLBC0422s/37: St 16:00–18:30 A16/213, E. Táborská
    aVLBC0422s/38: Út 14:00–16:30 A16/213, J. Tomandl
    aVLBC0422s/39: Út 14:00–16:30 A16/213, J. Tomandl
    Předpoklady
    aVLBC0321s Biochemistry I - seminar && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course, students understand the principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well-fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modelling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus. Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders.
    • Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration. Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO. Energetics of muscle work.
    • Steroidal, thyroidal hormones – synthesis, secretion, effects
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    Literatura
      povinná literatura
    • Seminar texts available in IS MUNI.
    • RODWELL, Victor W., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY a P. Anthony WEIL. Harper's illustrated biochemistry. Thirty-first edition. New York: McGraw-Hill, 2018, x, 789. ISBN 9781260288421. info
      doporučená literatura
    • LIEBERMAN, Michael, Allan D. MARKS a Alisa PEET. Marks' basic medical biochemistry : a clinical approach. Illustrated by Matthew Chansky. 4th ed. Baltimore: Lippincott, Williams & Wilkins, 2013, ix, 1014. ISBN 9781451100037. info
    Výukové metody
    Seminary course. Class discussions on assigned topics.
    Metody hodnocení
    Course-unit credit.
    Conditions for giving the course-unit credit (all conditions should be met):
  • completion of all lessons,
  • minimal success rate of 70 % from all revision tests or minimal success rate of 50 % from the credit test. The resit credit test can be taken only once.
    The detailed conditions are posted in IS MUNI (Study materials – Course-related instructions).
    • Vyučovací jazyk
    Angličtina
    Informace učitele
    https://is.muni.cz/auth/el/1411/jaro2022/aVLBC0422s/
    Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MUNI in the Course-related instructions. The syllabus is also posted on the notice board of the Department of Biochemistry.
    Consultations are possible after a personal arrangement with the teacher.
    Další komentáře
    Předmět je vyučován každoročně.
    Successful completion of the course is a condition for access to the exam in the course aVLBC0422p.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2020, jaro 2021, jaro 2023, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2021
    Rozsah
    0/3/0. 45. 2 kr. Ukončení: z.
    Vyučující
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    MUDr. Michaela Králíková, Ph.D. (cvičící)
    RNDr. Hana Paulová, CSc. (cvičící)
    Mgr. Jiří Slanina, Ph.D. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    Mgr. Marie Tomandlová, Ph.D. (cvičící)
    MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
    Garance
    prof. RNDr. Eva Táborská, CSc.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/30: Čt 15:00–17:30 A16/215, J. Tomandl
    aVLBC0422s/31: Čt 15:00–17:30 A16/215, J. Tomandl
    aVLBC0422s/32: Čt 12:00–14:30 A16/213, E. Táborská, J. Tomandl
    aVLBC0422s/33: Čt 12:00–14:30 A16/213, E. Táborská, J. Tomandl
    aVLBC0422s/34: Po 8:00–10:30 A16/215, E. Táborská, J. Tomandl
    aVLBC0422s/35: Po 8:00–10:30 A16/215, E. Táborská, J. Tomandl
    aVLBC0422s/36: Út 11:00–13:30 A16/215, E. Táborská, J. Tomandl
    aVLBC0422s/37: Út 11:00–13:30 A16/215, E. Táborská, J. Tomandl
    aVLBC0422s/38: Čt 12:00–14:30 A16/215, J. Dostál
    aVLBC0422s/39: Čt 12:00–14:30 A16/215, J. Dostál
    Předpoklady
    aVLBI0222p Lékařská biologie II - př && aVLBF011p Biophysics - lecture && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (aVLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literatura
      povinná literatura
    • Seminar texts available in Information system
    Výukové metody
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Metody hodnocení
    Conditions of giving the credits • Submission of all completed protocols with answers to the Homework Vaults in relevant dates. • Required attendance in seminars. • All absences must be made up according to teacher instructions. • Obtaining 52 points or more from continuous revision tests or • Obtaining 14 points from the credit test
    Vyučovací jazyk
    Angličtina
    Informace učitele
    Teaching in seminars will be realized in a contactless form, as online meetings in MS Teams environment, similarly as in the Autumn semester. The seminars will take place on the dates and times specified in the schedule. Online seminars will be teacher-moderated discussions to the given topic according to the syllabus of the course. The control questions of the given seminar topic intended for self-study and preparation for the discussion will be saved in the Study materials of the course. Attendance at online classes is mandatory, absences must be excused in IS MUNI. Maximally one unexcused absence per semester is tolerated. Like in previous semester, the up-load of a completed protocol to IS Homework Vault before the seminar date will be required. The deadline for submission is always the Sunday 24:00 for the seminar in the following week. Protocols must be provided for all seminar topics, even in case of absence from the seminar. In the 4th, 9th and 12th week, on Fridays, continuous revision online tests will be opened in the IS MUNI application at the same time for all students. These tests must be taken by all students. If students obtain at least 52/75 points from three continuous tests, they are awarded a credit without the obligation to write a credit test. (Excused absence from continuous tests can be made up in the credit week). The other students must take a credit test in the 15th week. The credit test covers the topics of all seminars and has 30 questions. The condition for giving the credit is to obtain 14 points. The credit test can be written after all absences are made up. Students who do not meet the conditions of the credit test in the credit week have the opportunity to repeat it once.
    Další komentáře
    Předmět je vyučován každoročně.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2020, jaro 2022, jaro 2023, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2020
    Rozsah
    0/3/0. 45. 2 kr. Ukončení: z.
    Vyučující
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    MUDr. Michaela Králíková, Ph.D. (cvičící)
    RNDr. Hana Paulová, CSc. (cvičící)
    Mgr. Jiří Slanina, Ph.D. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    Mgr. Marie Tomandlová, Ph.D. (cvičící)
    MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
    PharmDr. Katarína Kostolanská (pomocník)
    Garance
    prof. RNDr. Eva Táborská, CSc.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Kontaktní osoba: Monika Šudáková
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/30: Po 8:00–10:30 A16/215, J. Tomandl
    aVLBC0422s/31: Po 8:00–10:30 A16/215, J. Tomandl
    aVLBC0422s/32: Po 16:00–18:30 A16/215, J. Dostál
    aVLBC0422s/33: Po 16:00–18:30 A16/215, J. Dostál
    aVLBC0422s/34: Po 16:00–18:30 A16/213, E. Táborská
    aVLBC0422s/35: Po 16:00–18:30 A16/213, E. Táborská
    aVLBC0422s/36: St 13:00–15:30 A16/213, J. Tomandl
    aVLBC0422s/37: St 13:00–15:30 A16/213, J. Tomandl
    aVLBC0422s/38: Út 11:00–13:30 A16/213, E. Táborská
    aVLBC0422s/39: Út 11:00–13:30 A16/213, E. Táborská
    Předpoklady
    aVLBI0222p Biologie II - přednáška && aVLBF011p Biophysics - lecture && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (aVLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literatura
      povinná literatura
    • Seminar texts available in Information system
    Výukové metody
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Metody hodnocení
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry II.
    Vyučovací jazyk
    Angličtina
    Další komentáře
    Předmět je vyučován každoročně.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2019, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2019
    Rozsah
    0/3/0. 45. 2 kr. Ukončení: z.
    Vyučující
    Ing. Martina Čarnecká, Ph.D. (cvičící)
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    MUDr. Michaela Králíková, Ph.D. (cvičící)
    RNDr. Hana Paulová, CSc. (cvičící)
    Mgr. Jiří Slanina, Ph.D. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    Mgr. Marie Tomandlová, Ph.D. (cvičící)
    MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
    PharmDr. Katarína Kostolanská (pomocník)
    Lenka Nerudová (pomocník)
    Garance
    prof. RNDr. Eva Táborská, CSc.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/30: St 16:00–18:30 A16/213, J. Tomandl
    aVLBC0422s/31: Po 16:00–18:30 A16/213, J. Dostál
    aVLBC0422s/32: Po 10:00–12:30 A16/215, J. Tomandl
    aVLBC0422s/33: Po 10:00–12:30 A16/215, J. Tomandl
    aVLBC0422s/34: Po 16:00–18:30 A16/215, E. Táborská
    aVLBC0422s/35: Po 16:00–18:30 A16/213, J. Dostál
    aVLBC0422s/36: Út 11:00–13:30 A16/215, E. Táborská
    aVLBC0422s/37: Po 16:00–18:30 A16/215, E. Táborská
    aVLBC0422s/38: St 16:00–18:30 A16/213, J. Tomandl
    Předpoklady
    aVLBI0222p Biologie II - přednáška && aVLBF011p Biophysics - lecture && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (aVLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literatura
      povinná literatura
    • Seminar texts available in Information system
    Výukové metody
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Metody hodnocení
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry II.
    Vyučovací jazyk
    Angličtina
    Další komentáře
    Předmět je vyučován každoročně.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2018
    Rozsah
    0/3/0. 2 kr. Ukončení: z.
    Vyučující
    Ing. Martina Čarnecká, Ph.D. (cvičící)
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    MUDr. Michaela Králíková, Ph.D. (cvičící)
    RNDr. Hana Paulová, CSc. (cvičící)
    Mgr. Jiří Slanina, Ph.D. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    Mgr. Marie Tomandlová, Ph.D. (cvičící)
    Mgr. Jana Gregorová, Ph.D. (pomocník)
    MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
    PharmDr. Katarína Kostolanská (pomocník)
    Lenka Nerudová (pomocník)
    doc. Mgr. Ondřej Peš, Ph.D. (pomocník)
    Garance
    prof. RNDr. Eva Táborská, CSc.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/30: Út 10:20–12:50 A16/213, J. Dostál
    aVLBC0422s/31: Po 16:00–18:30 A16/213, J. Dostál
    aVLBC0422s/32: Út 10:20–12:50 A16/213, J. Dostál
    aVLBC0422s/33: St 12:45–15:15 A16/215, J. Tomandl
    aVLBC0422s/34: St 12:45–15:15 A16/215, J. Tomandl
    aVLBC0422s/35: Út 10:30–13:00 A16/215, E. Táborská
    aVLBC0422s/36: Út 10:30–13:00 A16/215, E. Táborská
    aVLBC0422s/37: Po 16:00–18:30 A16/213, J. Dostál
    Předpoklady
    aVLBI0222p Biologie II - přednáška && aVLBF011p Biophysics - lecture && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literatura
      povinná literatura
    • Seminar texts available in Information system
    Výukové metody
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Metody hodnocení
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry II.
    Vyučovací jazyk
    Angličtina
    Další komentáře
    Předmět je vyučován každoročně.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2017, jaro 2019, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.

    aVLBC0422s Biochemie II - seminář

    Lékařská fakulta
    jaro 2017
    Rozsah
    0/3/0. 2 kr. Ukončení: z.
    Vyučující
    Ing. Martina Čarnecká, Ph.D. (cvičící)
    doc. RNDr. Jiří Dostál, CSc. (cvičící)
    PharmDr. Katarína Kostolanská (cvičící)
    MUDr. Michaela Králíková, Ph.D. (cvičící)
    RNDr. Hana Paulová, CSc. (cvičící)
    Mgr. Jiří Slanina, Ph.D. (cvičící)
    prof. RNDr. Eva Táborská, CSc. (cvičící)
    doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
    Mgr. Marie Tomandlová, Ph.D. (cvičící)
    Mgr. Jana Gregorová, Ph.D. (pomocník)
    MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
    Lenka Nerudová (pomocník)
    doc. Mgr. Ondřej Peš, Ph.D. (pomocník)
    Garance
    prof. RNDr. Eva Táborská, CSc.
    Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
    Rozvrh seminárních/paralelních skupin
    aVLBC0422s/30: Út 10:20–12:50 A16/213, J. Dostál
    aVLBC0422s/31: Po 16:00–18:30 A16/213, J. Dostál
    aVLBC0422s/32: Út 10:20–12:50 A16/213, J. Dostál
    aVLBC0422s/33: St 12:45–15:15 A16/215
    aVLBC0422s/34: St 12:45–15:15 A16/215
    aVLBC0422s/35: Út 10:30–13:00 A16/215
    aVLBC0422s/36: Út 10:30–13:00 A16/215
    aVLBC0422s/37: Po 16:00–18:30 A16/213, J. Dostál
    Předpoklady
    aVLBI0222p Biologie II - přednáška && aVLBF011p Biofyzika - přednáška && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
    Omezení zápisu do předmětu
    Předmět je určen pouze studentům mateřských oborů.
    Mateřské obory/plány
    Cíle předmětu
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Výstupy z učení
    The student is able:
    - to explain the interrelationship between the metabolism of nutrients under different states of the organism.
    - to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
    - to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
    - to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
    - to explain the principles of metabolism regulation at all levels.
    Osnova
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literatura
      povinná literatura
    • Seminar texts available in Information system
    Výukové metody
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Metody hodnocení
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry II.
    Vyučovací jazyk
    Angličtina
    Další komentáře
    Předmět je vyučován každoročně.
    Nachází se v prerekvizitách jiných předmětů
    Předmět je zařazen také v obdobích jaro 2018, jaro 2019, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.