aZLBC0422s Biochemistry II - seminar

Faculty of Medicine
spring 2026
Extent and Intensity
0/2.8/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
RNDr. Hana Paulová, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Iva Audy (assistant)
doc. RNDr. Jiří Dostál, CSc. (assistant)
Mgr. Jana Gregorová, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (assistant)
doc. Mgr. Ondřej Peš, Ph.D. (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
Mgr. Jindra Smutná, Ph.D. (assistant)
prof. RNDr. Eva Táborská, CSc. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: MUDr. Michaela Králíková, Ph.D.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Prerequisites (in Czech)
aZLLC011p Med Chem, Dental Mat - lect && aZLBF011p Med.Physics and Informat.-lect && aZLBI0222p Biology II-lect. && ( aZLBC0221s Biochemistry I - seminar || aZLBC0321s Biochemistry I - seminar )
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to the Biochemistry lecture. The knowledge of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of the organism (well-fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome)are thoroughly practised during Biochemistry seminars.
Learning outcomes
The student will be able to:
- explain the interrelationship between the metabolism of nutrients under different states of the organism.
- describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
- understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
- discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
- explain the principles of metabolism regulation at all levels.
Syllabus
  • Factors influencing laboratory tests, interpretation of results. Diagnostic accuracy.
  • Enzymes in diagnostics.
  • Blood glucose homeostasis, metabolic disorders in diabetes mellitus.
  • Protein quality. Protein and amino acid transformations in different states.
  • Blood plasma lipids. Lipoprotein transformations. Cholesterol transport.
  • Nutrient transformations in different states. Energy balance, obesity, metabolic syndrome.
  • Role of the liver in metabolism of nutrients, hormones and vitamins. Catabolism of heme.
  • Metabolism of iron and copper.
  • Biotransformation of xenobiotics. Alcohol metabolism.
  • Water homeostasis, Na+ and K+. Regulation of osmolality and volemia. Disorders of water homeostasis.
  • Acid-base balance and disorders. Transport of O2 and CO2.
  • Kidney functions.
  • Receptors and signal transduction.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle activity.
  • Metabolism of calcium, magnesium, phosphorus, fluorine and iodine.
  • Metabolism of hard tissues.
  • Biochemistry of oral cavity.
Literature
    required literature
  • Interactive Syllabus of the course in IS MU.
  • FERRIER, Denise R. Biochemistry. Seventh edition. Philadelphia: Wolters Kluwer, 2017, viii, 567. ISBN 9781496363541. info
    recommended literature
  • VASUDEVAN, D. M.; S. SREEKUMARI and Kannan VAIDYANATHAN. Textbook of biochemistry for dental students. 3rd edition. New Delhi: Jaypee, 2017, xiii, 289. ISBN 9789352701148. info
Teaching methods
Seminary course. Class discussions on assigned topics.
Assessment methods
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Language of instruction
English
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught every week.
General note: Successful completion of the course is a condition for access to the exam in the course aZLBC0422p.
Listed among pre-requisites of other courses

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Teacher's information
Detailed information on the teaching and completion of the course is given in the Study Materials in IS MU.
Consultations are possible after a personal arrangement with the teacher.
The course is also listed under the following terms spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (spring 2026, recent)
  • Permalink: https://is.muni.cz/course/med/spring2026/aZLBC0422s