Course Information

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

Ing. Vojtěch Hudzieczek, Ph.D. (lecturer)
prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Ing. Václav Bačovský, Ph.D. (lecturer)

Guaranteed by

Ing. Vojtěch Hudzieczek, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Ing. Vojtěch Hudzieczek, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Prerequisites

SOUHLAS || Bi4010 Essential molecular biology || Bi4020 Molecular biology
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Ing. Vojtěch Hudzieczek, Ph.D. (lecturer)
Ing. Václav Bačovský, Ph.D. (lecturer)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 15:00–16:50 E25/209

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6401 Bc Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Ing. Vojtěch Hudzieczek, Ph.D. (lecturer)
Ing. Václav Bačovský, Ph.D. (lecturer)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6401 Bc Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Ing. Vojtěch Hudzieczek, Ph.D. (assistant)
Ing. Václav Bačovský, Ph.D. (assistant)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6401 Bachelor Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught partially online.

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal Genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 16 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

required literature
• VYSKOT, Boris. Epigenetika. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2010, 150 s. ISBN 9788024425344. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

recommended literature
• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 17. 9. to Fri 14. 12. Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 18. 9. to Fri 15. 12. Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
Mgr. Ivana Kupčíková, DiS. (assistant)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 19. 9. to Sun 18. 12. Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4020 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Learning outcomes

At the end of this course students will be able to understand the specific laws of ontogenesis of plants, animals and humans and molecular mechanisms of development processes including genomic imprinting.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphallaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostelium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, positional cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophyte and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers which are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 12 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor sate exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Developmental genetics is presented as a global survey of principles of developmental processes. It is also presented as comparative science in order to demonstrate common features of developmental processes in phylogenetically distant groups of organisms. We will focus on genetic and epigenetic fundamentals of developmental processes on molecular level. The topic is divided into ten chapters and students receive their adequate e-presentations.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis) (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Assessment methods

oral exam

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 BFU

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 B1,01004

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Timetable

Mon 14:00–15:50 B1,01004

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Boris Vyskot, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

The information about the term Autumn 2011 - acreditation is not made public

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Basic genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

At the end of this course, students should be able to understand common features of developmental processes in phylogenetically distant groups of organisms, genetic and epigenetic fundamentals of developmental processes on molecular level.

Syllabus

• (1) General principles of developmental genetics, history, embryonic induction (Spemann), models of flags (Wolpert), reaction-diffuse model of development (Turing), regulative and mosaic development, homeosis (Bateson, Goethe), programmed cell death, preformism and epigenesis (Aristotle), germ-line (Weismann), genes with maternal effects, morphalaxis and epimorphosis
• (2) Developmental and epigenetic processes in bacteria (Bacillus subtilis), fungi (yeast, Dictyostellium) and primitive animal models (Paramecium, Hydra, Caenorhabditis)
• (3) Flatworms – rediscovered model of developmental biology: regeneration, neurobiology, allometry, RNA-interference
• (4) Drosophila melanogaster – the queen of developmental genetics: genetic control cascade of embryogenesis, maternal and zygotic genes, homeotic genes, colinearity, imaginal discs, homeotic transdetermination
• (5) Deuterostomia as important models for developmental studies: sea urchin, fish, amphibians, birds, mammals
• (6) Medical aspects of developmental biology: therapy of infertility, malformations, teratogenesis, candidate genes, position cloning, stem cells, DNA therapy, epigenetic diseases
• (7) Alternative models of plant developmental genetics: Anabaena, Acetabularia, Chlamydomonas, Volvox, Fucus, Marchantia, Physcomitrella, Ceratopteris, Populus, Antirrhinum, Linaria, Linum, Craterostigma, Zinnia, Silene, Zea, Oryza, Brachypodium, Gagea, Eleocharis, orchids
• (8) Arabidopsis thaliana model: gametophye and sporophyte, imprinting in endosperm, control of embryogenesis, regulative development, control of flowering, MADS-box genes, homeobox genes, Polycomb proteins (Medea), paramutations, epimutations
• (9) Sex and its determination, genetically, hormone and epigenetically controlled sexuality, structure and evolution of sex chromosomes, gynandromorphy, dioecy, X- and Y-linked inheritance, molecular mechanisms of sex determination
• (10) Principles of epigenetic inheritance, mechanisms of epigenetic processes, evolutionary and developmental processes (or evo/devo): heterotopic changes, heterochronic changes, environmental adaptation

Literature

• Principles of developmental genetics. Edited by Sally A. Moody. Boston: Elsevier Academic Press, 2007, xiv, 1055. ISBN 9780123695482. info
• VYSKOT, Boris. Přehled vývojové biologie a genetiky. Praha: Ústav molekulární genetiky AV ČR, 1999, 241 s. ISBN 80-902588-1-6. info

Teaching methods

Lectures are based on power-point pictures, tables and texts elaborated according to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries.

Assessment methods

Oral examination follows the written test in which students should answer 50 questions covering main topics of the lecture. During the oral examinations the students have to prove their knowledge on particular examples. To pass the exam they should answer 70% of the answers.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

Bi0580 Developmetal genetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Boris Vyskot, DrSc. (lecturer), prof. RNDr. Jiřina Relichová, CSc. (deputy)

Guaranteed by

prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Boris Vyskot, DrSc.

Prerequisites

( SOUHLAS || Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Ex_3065 Molekulární biologie || Imp_9115 Molekulární biologie || B3120 Molecular and cell biology || B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology )
Foreign students are welcome (a relevant literature in English is available).

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Cílem semestrálního kurzu je seznámit studenty s obecnými i specifickými zákonitostmi ontogeneze rostlin, živočichů i člověka. Zvláštní důraz je kladen na molekulární mechanizmy vývojových procesů včetně genomového imprintingu.

Syllabus

• DEVELOPMENTAL GENETICS: 1 Basic processes in development of eukaryotic organisms 1.1 History of developmental biology 1.2 Basic terms in developmental biology and genetics 2 Reproduction processes in animals and plants 2.1 Asexual reproduction 2.2 Sexual reproduction 2.2.1 Gametes and fertilization 3 Early development in animals 3.1 Cleavage and gastrulation 3.2 Differentiation and pattern formation 3.3 Theories and models of development 4 Biology and genetics of development on model organisms 4.1 Animals 4.1.1 Dictyostelium discoideum 4.1.2 Hydra 4.1.3 Caenorhabditis elegans 4.1.4 Drosophila melanogaster 4.1.5 Vertebrates 4.2 Plants 4.2.1 Acetabularia 4.2.2 Fucus 4.2.2 Angiosperm plants 4.3 Comparison of animal and plant development 5 Molecular control of developmental processes 5.1 Control of transcription and posttranscriptional processes 5.2 Maternal genes 5.3 Homeotic genes, structure and function 5.4 Role of proteins with chromodomains 5.5 Specific features of differentiation in animals and plants 6 Control of sex differentiation 6.1 Principles of sex determination in animals and plants 6.1.1 Genetic control of sex determination 6.1.2 Sex chromosomes, structure and function 6.1.3 Environmental sex determination 6.2 Germ line and control of sexual phenotype 7 Epigenetic processes in development 7.1 Chromatin structure and modification 7.1.1 DNA methylation 7.1.2 Acetylation of nucleosomal histones 7.2 Genomic imprinting and parental conflict 7.2.1 Role of genomic imprinting in mammals 7.2.2 Imprinting in plant endosperm 7.3 Gene silencing, principles and practice 7.3.1 Constitutive and facultative heterochromatin 7.3.2 Mechanisms of gene dosage compensation 7.3.3 Paramutation, position-variegation effect and transvection

Literature

• B. Vyskot: Přehled vývojové biologie a genetiky. Skriptum, ÚMG AV Praha, 1999 (ISBN 80-902588-1-6)

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

http://www.ibp.cz/labs/PDG/

• Enrolment Statistics (Autumn 2024, recent)