aZLFA0621c Farmakologie I - cvičení

Lékařská fakulta
jaro 2027
Rozsah
0/2/0. 30. 2 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
doc. MUDr. Regina Demlová, Ph.D. (cvičící)
doc. PharmDr. Jan Juřica, Ph.D. (cvičící)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (cvičící)
Carlos Daniel Ferreira Fonseca, MSc. (cvičící)
Garance
doc. MUDr. Regina Demlová, Ph.D.
Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Dodavatelské pracoviště: Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Předpoklady
aZLPA0521c Patologie I - cvičení && aZLPF0521c Patol. fyziologie I - cv. && aZLCP051c Chirurgická propedeutika -cv.

The student has completed courses aZLPA0521c, aZLPF0521c, aZLCP051c.

Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Anotace
This course is designed to deepen and provide practical application of the knowledge gained in the course aZLFA0621p.
Výstupy z učení
After finishing the course the student will be able:
- to use formally correct terminology belonging to the valid Pharmacopoea. - to prescribe ready-made drug dosage forms.
- to understand basic principles of pharmacokinetics, pharmacodynamics, routes of admninistration and adverse effects - tu understand pharmacology of drugs affecting autonomic nervous system and GIT, pharmacology of glucocorticods, antihistamines, drugs used for treatment of diseases with bronchial obstruction, cough, diabetes, obesity and dyslipidemia.
Klíčová témata
    • Pharmacology - practical courses

    • Dentistry

    • Spring semester 

    • /1/
    • INTRODUCTION TO THE STUDY OF PHARMACOLOGY, ROUTES OF DRUG APPLICATION, DOSAGE FORMS, SOURCES OF INFORMATION ON DRUGS
    • Contents of the study of Pharmacology, contents and organization of theoretical and practical courses and lectures, required and recommended textbooks. The conditions for granting the credit. Pharmacology - drug nomenclature. Classification of application methods with examples of drugs. Classification and overview of dosage forms for mass production and individual preparation, advantages and disadvantages of each type of dosage form in clinical use, typical excipients. Controlled release dosage forms. Sources of information on pharmaceuticals. Working with the SÚKL, EMA and AISLP databases, ATC classification. Pharmacopoeia.

    • /2/
    • DRUG PRESCRIPTION
    • Examples of prescription in different countries. Essential terminology for prescription. Rules for prescription of ready-made preparations.

    • /3/
    • /PHARMACODYNAMICS AND PHARMACOKINETICS
    • Examples of mechanisms of action and their practical applications. Pharmacokinetic case reports.

    • /4/
    • INTRODUCTION TO PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM + PHARMACOLOGY OF PARASYMPATHETIC SYSTEM
    • TEST I
    • Receptors of cholinergic (parasympathetic) system, pharmacology of drugs activating and blocking cholinergic (parasympathetic) system.

    • /5/
    • PHARMACOLOGY OF SYMPATHETIC SYSTEM
    • Receptors of noradrenergic (sympathetic) system, pharmacology of drugs activating and blocking noradrenergic (sympathetic) system.

    • /6/
    • GLUCOCORTICOIDS AND DRUGS AFFECTING BONE METABOLISM
    • A basic pharmacological characterization of glucocorticoids; agents used in the treatment of osteoporosis.

    • /7/
    • H1-ANTIHISTAMINES, DRUGS FOR TREATMENT OF DISEASE WITH BRONCHIAL OBSTRUCTION, DRUGS USED FOR COUGH THERAPY
    • TEST II
    • Effects of histamine and possibilities of their antagonization. Basic pharmacological overview of drugs used to treat chronic bronchial obstruction. Drugs used for cough therapy.
    • /8/
    • DRUGS USED IN GASTROINTESTINAL TRACT
    • PRESCRIPTION TEST
    • Antiemetics, antiulcer agents, hepatoprotective agents, prokinetics, laxatives, antidiarrheals. Basic pharmacological characteristics of neurotropic and musculotropic antispsamodics.
    • /9/ 
    • DRUGS FOR TREATMENT OF DIABETES MELLITUS, OBESITY AND DYSLIPIDEMIA
    • Review of drugs of antidiabetic drugs - bassic pharmacological charachteristics. Combinations of insulin regimens. Drugs used in dyslipidemias, antiobesics.

    • /10/
    • CASE REPORTS, DRUG INTERACTIONS 
    • TEST III
    • A summary review of the material covered using selected case studies. Classification and review of significant drug interactions, including interactions with dietary supplements or food.
    • CREDITS

Studijní zdroje a literatura
    povinná literatura
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN a H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
  • For English speaking students: Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • Selected chapters from general pharmacology for students of general medicine and dentistry at FM MU, https://portal.med.muni.cz/discipline-13-pharmacology
    doporučená literatura
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
Přístupy, postupy a metody používané ve výuce
In the practicals, the topics discussed are practiced as group and individual activities supplemented by the teacher's explanations and discussions. An essential part of the teaching is the students' home preparation for individual lessons and self-study.
Způsob ověření výstupů z učení a požadavky na ukončení
Participation in practical exercises is compulsory. One unexcused absence is allowed. There are four tests in total in the practical exercises:

Prescription test (8th exercise)
- contains 2 Ready-made products
- the active substance is indicated in the entry for the IPP and the pharmacotherapeutic group or indication for the RMP
- for both preparations, the pharmaceutical form and the quantity of the preparation
- rating: pass/fail
- the time limit is 30 minutes
- can be repeated a maximum of twice

Multiple-choice tests (Exercises 4, 7 and 10)
- on knowledge of the material covered
- the test consists of  10 questions with  3 to 5 multiple choice questions
- the number of correct answers is given at the end of the question
- points are awarded for questions answered completely correctly (2 points)
- the limit for passing the test is 10 points
- only one of the tests can be repeated and only once

TEST
In order to pass:
90% attendance at practice
Successful completion of the Prescription Test
Successful completion of three Multiple-choice tests with minimal score of 36 points.

Multiple-choice test results count towards the final grade for Pharmacology II (aZLFA0721p)
Náhradní absolvování
The course cannot be completed in an alternative form. In the event of long-term illness or an internship abroad, please contact the course coordinator.
Vyučovací jazyk
Angličtina
Navazující předměty
Odkaz a informace vyučujících
https://is.muni.cz/auth/el/1411/jaro2027/aZLFA0621c/
Information for students:
Classes are held in classrooms according to the timetable listed in the IS.
Due to public holidays, some classes will be taught with other topics. The respective seminar groups will be informed of this fact by e-mail well in advance.

The teaching of pharmacology to students of dental medicine is conducted on a two-semester basis.
In the spring semester, the course is completed with credit. See above for credit requirements.
Completion in the autumn semester = rigorous examination, which consists of a pre-test and an oral part.
The oral exam consists of three randomly selected questions from the headings:
1) general pharmacology
2) special pharmacology
3) selected chapters of special pharmacology relevant to ZL students

The results of the multiple-choice test from practicals and pre-exam tests are included in the final grade, see the aZL Continuous Assessment System document in the Study materials.
Studijní opora
https://is.muni.cz/auth/el/1411/jaro2027/aZLFA0621c/
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