Medical Biology II

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Lékařská biologie II - cvičení

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular backgrounds in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practising selected molecular methods used for the examination of some cancers or hereditary and infectious diseases with regard to the selection of appropriate therapy

Rozvrh seminárních/paralelních skupin:
aVLBI0222c/30 Po 16. 2. až Čt 14. 5. Čt 11:00–11:30 B07/214, Čt 11:30–13:00 B07/214, Čt 11:30–13:00 B07/217, Čt 13:00–13:30 B07/214
aVLBI0222c/31 Po 16. 2. až Po 11. 5. Po 11:30–12:00 B07/214, Po 12:00–13:30 B07/217, Po 12:00–13:30 B07/214, Po 13:30–14:00 B07/214
aVLBI0222c/32 Po 16. 2. až Čt 14. 5. Čt 8:00–8:30 B07/214, Čt 8:30–10:00 B07/214, Čt 8:30–10:00 B07/217, Čt 10:00–10:30 B07/214
aVLBI0222c/33 Po 16. 2. až St 13. 5. St 8:00–8:30 B07/214, St 8:30–10:00 B07/217, St 8:30–10:00 B07/214, St 10:00–10:30 B07/214, kromě St 13. 5., kromě, kromě, kromě
aVLBI0222c/34 Po 16. 2. až Út 12. 5. Út 10:30–11:00 B07/214, Út 11:00–12:30 B07/214, Út 11:00–12:30 B07/217, Út 12:30–13:00 B07/214
aVLBI0222c/35 Po 16. 2. až Pá 15. 5. Pá 9:00–9:30 B07/214, Pá 9:30–11:00 B07/214, Pá 9:30–11:00 B07/217, Pá 11:00–11:30 B07/214
aVLBI0222c/36 Po 16. 2. až Út 12. 5. Út 13:30–14:00 B07/214, Út 14:00–15:30 B07/217, Út 14:00–15:30 B07/214, Út 15:30–16:00 B07/214
aVLBI0222c/37 Po 16. 2. až Út 12. 5. Út 7:30–8:00 B07/214, Út 8:00–9:30 B07/217, Út 8:00–9:30 B07/214, Út 9:30–10:00 B07/214
aVLBI0222c/38 Po 16. 2. až St 13. 5. St 11:00–11:30 B07/214, St 11:30–13:00 B07/217, St 11:30–13:00 B07/214, St 13:00–13:30 B07/214, kromě St 13. 5., kromě, kromě, kromě
aVLBI0222c/39 Po 16. 2. až St 13. 5. St 14:00–14:30 B07/214, St 14:30–16:00 B07/217, St 14:30–16:00 B07/214, St 16:00–16:30 B07/214, kromě St 13. 5., kromě, kromě, kromě
Lékařská fakulta

Vyučující

prof. RNDr. Ondřej Slabý, Ph.D.
(přednášející)
• profesní životopis

Neeraj Bhavani Aniyan Bhavana
(cvičící)

Mgr. Andrej Bešše, Dr. sc. nat.
(cvičící)

Mgr. Lenka Bešše, Ph.D.
(cvičící)

Mgr. Kateřina Cetkovská, Ph.D.
(cvičící)

Ing. Lívia Eiselleová, Ph.D.
(cvičící)

Mgr. Kateřina Francová, Ph.D.
(cvičící)

Martin Hanák
(cvičící)

Mgr. Nikola Kaštánková
(cvičící)

Mgr. Viktor Kostohryz
(cvičící)

Mgr. Kateřina Kučerová, Ph.D.
(cvičící)

Mgr. Anna Lešková
(cvičící)

Mgr. Petra Pospíšilová, Ph.D.
(cvičící)

Mgr. František Siegl
(cvičící)

Ing. Natália Vadovičová
(cvičící)

Mgr. Kateřina Vopěnková, Ph.D.
(cvičící)

Osnova

Week 1: Genetic disorders - autosomal and gonosomal inheritance
Week 2: Extensions to basic genetics
Week 3: Genetic prognosis and genetic counselling
Week 4: Human population genetics
Week 5: Basic methods of molecular biology II
Week 6: Control test 3 (knowledge from week 1 to week 5 of the spring semester - lectures, practices)
Week 7: Molecular diagnostics of human pathogenic bacteria
Week 8: Molecular diagnostics of human pathogenic bacteria
Week 9: Molecular diagnostics of cancer
Week 10: Molecular diagnostics of cancer
Week 11: Gene engineering – production of human proteins in bacterial cells
Week 12: Gene engineering – production of human proteins in bacterial cells
Week 13: Control test 4 (knowledge from week 7 to week 12 of the spring semester - lectures, practices)
Week 14: no practices, Re-sit test
Week 15: no practices, credit awarding

Informace učitele

https://is.muni.cz/auth/el/med/jaro2026/aVLBI0222c/index.qwarp
Interactive syllabus of the course: https://is.muni.cz/auth/el/med/jaro2026/aVLBI0222c/index.qwarp

What to bring to each practice: printed protocol for the respective practice, your writing materials. Download the protocol for each practice from the Study materials or Interactive syllabus in the IS, and study it in advance. Lab shoes are required, and lab coats and disposable gloves are not required, but lab coats are recommended for tasks with staining.
Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum), students can arrange a substitution with another group. To arrange a substitution, write an e-mail to the course contact person at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead (see Interactive syllabus - Instructions for the course - Timetable). Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.
Complete Biology instructions to be found at the following link:
https://is.muni.cz/auth/el/med/jaro2026/aVLBI0222c/op/Biology_practices_instructions.pdf?predmet=1482172

Lékařská biologie II - přednáška

The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering and evolutionary biology

Rozvrh: jaro 2026
Po 16. 2. až Čt 14. 5. Čt 16:00–17:40 B11/334
Lékařská fakulta

Vyučující

prof. RNDr. Ondřej Slabý, Ph.D.
(přednášející)
• profesní životopis

prof. MUDr. David Šmajs, Ph.D.
(přednášející)
• profesní životopis

prof. MUDr. Iva Slaninová, Ph.D.
(přednášející)
• profesní životopis

Mgr. Bc. Stjepan Uldrijan, CSc.
(přednášející)

Mgr. Vladimír Rotrekl, Ph.D.
(přednášející)

Mgr. Kateřina Cetkovská, Ph.D.
(přednášející)

Ing. Lívia Eiselleová, Ph.D.
(přednášející)

Mgr. Kateřina Francová, Ph.D.
(přednášející)

Mgr. Kateřina Kučerová, Ph.D.
(přednášející)

doc. Mgr. Jiří Šána, Ph.D.
(přednášející)

Mgr. Kateřina Vopěnková, Ph.D.
(přednášející)

Osnova

Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance, Chromosome Abnormalities
Introduction to Genetics II – Multifactorial Inheritance, Genetic Linkage, Population Genetics
Human Genome
Epigenetics – Interaction of Genes and Environment
Immunogenetics
Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
Cancer Biology II – Application of Cancer Biology into Cancer Diagnostics and Therapy
Bacterial and Viral Genomics
Gene Therapy
Human Microbiome
Stem Cells and Tissue Engineering
Introduction to Human Ontogeny (Pre- and Postnatal Development)
Evolutionary Biology

Informace učitele

https://is.muni.cz/auth/el/med/jaro2026/aVLBI0222p/index.qwarp
Lectures take place every week. We recommend following the Interactive syllabus of the course, where students can find all relevant information (schedule, substitutions, public holidays etc.), and also lectures presentations and study literature, links to animations and videos relevant to the topic https://is.muni.cz/auth/el/med/jaro2026/aVLBI0222p/index.qwarp

Celková cena: 30 000 Kč vč. DPH

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