VLFA0722c Pharmacology II - practice

Faculty of Medicine
Autumn 2015
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (alternate examiner)
doc. PharmDr. Jana Rudá, Ph.D. (seminar tutor)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
PharmDr. Miroslav Turjap, Ph.D. (seminar tutor)
MVDr. Zuzana Babinská, Ph.D. (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
MVDr. Eva Dražanová, Ph.D. (seminar tutor)
Taher Kebab (seminar tutor)
Mgr. Hana Kostková (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
Dr. Vincenzo Micale, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
Mgr. Gabriela Přibyl Dovrtělová, Ph.D. (seminar tutor)
MUDr. Petra Řiháčková, MBA (seminar tutor)
PharmDr. Irena Sehnalová, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
MUDr. Mgr. Karel Šlais, Ph.D. (seminar tutor)
Mgr. Tibor Štark (seminar tutor)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: Renata Bláblová
Supplier department: Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Timetable of Seminar Groups
VLFA0722c/01: Mon 5. 10. to Fri 16. 10. each working day 7:30–12:20 A19/231, except Wed 7. 10., except Thu 15. 10.
VLFA0722c/02: Mon 21. 9. to Fri 2. 10. each working day 7:30–12:20 A19/231, except Wed 23. 9., except Thu 1. 10.
VLFA0722c/04: Mon 14. 12. to Fri 18. 12. each working day 7:30–12:20 A19/231, Mon 4. 1. to Fri 8. 1. each working day 7:30–12:20 A19/231, except Wed 16. 12., except Thu 7. 1.
VLFA0722c/05: Mon 30. 11. to Fri 11. 12. each working day 7:30–12:20 A19/231, except Wed 2. 12., except Thu 10. 12.
VLFA0722c/06: Mon 16. 11. to Fri 27. 11. each working day 7:30–12:20 A19/231, except Wed 18. 11., except Thu 26. 11.
VLFA0722c/07: Mon 11. 1. to Fri 22. 1. each working day 7:30–12:20 A19/231, except Wed 13. 1., except Thu 21. 1.
VLFA0722c/08: Mon 19. 10. to Fri 30. 10. each working day 7:30–12:20 A19/231, except Wed 21. 10., except Thu 29. 10.
VLFA0722c/09: Mon 16. 11. to Fri 27. 11. each working day 7:30–12:20 A19/231, except Wed 18. 11., except Thu 26. 11.
VLFA0722c/10: Mon 2. 11. to Fri 13. 11. each working day 7:30–12:20 A19/231, except Wed 4. 11., except Thu 12. 11.
VLFA0722c/11: Mon 19. 10. to Fri 30. 10. each working day 7:30–12:20 A19/231, except Wed 21. 10., except Thu 29. 10.
VLFA0722c/12: Mon 5. 10. to Fri 16. 10. each working day 7:30–12:20 A19/231, except Wed 7. 10., except Thu 15. 10.
VLFA0722c/15: Mon 14. 12. to Fri 18. 12. each working day 7:30–12:20 A19/231, Mon 4. 1. to Fri 8. 1. each working day 7:30–12:20 A19/231, except Wed 16. 12., except Thu 7. 1.
VLFA0722c/16: Mon 30. 11. to Fri 11. 12. each working day 7:30–12:20 A19/231, except Wed 2. 12., except Thu 10. 12.
VLFA0722c/30: No timetable has been entered into IS.
VLFA0722c/31: No timetable has been entered into IS.
VLFA0722c/32: No timetable has been entered into IS.
VLFA0722c/33: No timetable has been entered into IS.
VLFA0722c/34: No timetable has been entered into IS.
Prerequisites (in Czech)
VLFA0621c Pharmacology I - p && ( VSAJ0222 English 1 II -p || VSCJ0686 Czech for Foreigners VI -p || VSNJ0222 German 1 II -p || VSSJ0222 Spanish 1 II -p )
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course student should be able to prescribe representatives of individual drug classes in the form of individually prepared pharmaceutical preparation and bulk drugs. The student should be familiar with pharmacological profiles of therapeutic and adverse effects of particular drugs with an attention paid to common drug-drug interactions.
Syllabus
  • VLFA0722c Pharmacology II- practicals

    Autumn semester 2015

  • Day 1 (Monday)
  • Introduction, instructions. Distribution of co-talks.
  • 1/ANALGESICS.
  • Opioid analgesics. Pharmacotherapy of pain. Opioid addiction therapy. Prescription and practical use of analgesic preparations.
  • 2/NON-STEROIDAL ANTIINFLAMMATORY DRUGS, DRUGS USED IN GOUT, ANTIPYRETICS.
  • Mechanisms of action and classification of anti-inflammatory and anti- rheumatic drugs (NSAIDs and the 2nd-line agents). Drugs used in therapy of gout.
  • Getting ready for the next lesson: Central neurotransmitters and sites of drug effects in CNS. Basic psychical functions.
  • Day 2 (Tuesday)
  • 3/PSYCHOTROPIC DRUGS – INTRODUCTION. ANXIOLYTICS, HYPNOSEDATIVES.
  • Classification and terminology of psychotropics. Review of their mechanisms of action. Pharmacology of anxiolytics and hypnosedatives. Mechanism of action of benzodiazepines. Prescription of hypnosedatives and psychostimulants.
  • Co-talks.
  • 4/ANTIDEPRESSANTS.
  • Classification and terminology of antidepressants. Review of their mechanisms of action, adverse effects, interactions.
  • Co-talks.
  • Getting ready for the next lesson: Allergic reactions – causes and mechamisms. Revision of PNS pharmacology - β2 mimetics, parasympatholytics. Glucocorticoids.
  • Day 3 (Wednesday)

    No classes.

  • Day 4 (Thursday)
  • REVISING TEST I (Revision test with subsequent discussion) Lesson 1 – 4.
  • 5/CASE REPORTS I.
  • Selected case reports on drugs from previous lessons. (including Pharmacology I lessons).
  • 6/ H1 ANTIHISTAMINES, ANTIASTHMATICS.
  • Classification and clinical use of H1 antihistamines. Pathophysiology of bronchial asthma, sites and mechanisms of action of antiasthma drugs. Prescription of antitussives, expectorants, antiasthmatics.
  • Co-talks.
  • Getting ready for the next lesson: Structure of bacterial cell, basis of antimicrobial therapy.
  • Day 5 (Friday)
  • 7/ANTIMICROBIAL AGENTS I.
  • Classification, mechanisms of action, combinations of antibiotics and chemotherapeutics.
  • Co-talks.
  • 8/ANTIMICROBIAL AGENTS II., CHEMOTHERAPEUTICS, THERAPY OF INFECTIOUS DIARRHEAS AND UROINFECTIONS.
  • Drugs acting in intestinal and urinary infections.
  • Co-talks.
  • Getting ready for the next lesson: Physiology of blood pressure regulation. Revision of PNS pharmacology-α1 sympatotholytics, α2 sympathomimetics, β sympatholytics.
  • Day 6 (Monday)
  • REVISING TEST II (Overhead-test with subsequent discussion). Lessons 5 - 8.
  • 9/HYPOLIPIDEMICS, THERAPY OF OBESITY.
  • Therapy of hyperlipoproteinaemia and hypercholesterolaemia, review of drugs and their mechanism of action.
  • Co-talks.
  • 10/ANTIHYPERTENSIVE AGENTS.
  • Introduction, classification, diuretics, beta blockers, ACE inhibitors, Ca 2+ blockers, and other hypertensives.
  • Co-talks.
  • Getting ready for the next lesson: : Revision of blood coagulation; patophysiology of cancer disease.
  • Day 7 (Tuesday)
  • 11/ANTICOAGULANTS AND THROMBOLYTICS.
  • Fibrinolytics, haemostatics, therapy of haemopoietic disorders.
  • Co-talks.
  • 12/PHARMACOLOGY OF ANTICANCER DRUGS.
  • Classification, mechanisms of action, side effects.
  • Co-talks.
  • Getting ready for the next lesson: : Drug dosage forms and external routes of drug administration, revision of drug prescription. Autonomic nervous system – catecholamines, atropine. Myorelaxants. Revision of prescription of drug dosage forms for external use.
  • Day 8 (Wednesday)
  • FINAL PRESCRIPTION TEST (includes dermatology).
  • 13/REVIEW OF DRUGS USED IN DERMATOLOGY.
  • Adstringents, epitelizants, antihidrotics, antiinfectives. Therapy of acne, psoriasis and seborrhea. Classification, mechanisms of action, side effects.
  • 14/GENERAL AND LOCAL ANAESTHETICS
  • Combined and balanced anaesthesia. Signs and stages of general anaesthesia. Inhaled and injected anaesthetics - classification and characteristics. Review of drugs used in premedication.
  • Co-talks.
  • Getting ready for the next lesson: Revision of lessons 9-14.
  • Day 9 (Thursday)

    No classes.

  • Day 10 (Friday)
  • REVISING TEST III (Overhead-test with subsequent discussion). Lessons 9 - 14.
  • 15/CASE REPORTS II.
  • Selected case reports on drugs from previous lessons. (including Pharmacology I lessons).
  • CREDITS.
Literature
    required literature
  • LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007. xxiv, 672. ISBN 9788072623730. info
    recommended literature
  • HADAŠOVÁ, Eva, Jana NOVÁKOVÁ, Jana PISTOVČÁKOVÁ, Jana VINKLEROVÁ, Alexandra ŠULCOVÁ and Olga STAROBOVÁ. Praktická cvičení z farmakologie (Practical lessons on pharmacology). 2. opravené a doplněné vyd. Brno: Vydavatelství MU Brno-Kraví Hora, 2003. 110 pp. Skripta. ISBN 80-210-2694-4. info
  • RANG, H. P. Rang & Dale's pharmacology. 8th ed. [Edinburgh]: Churchill Livingstone, 2016. xv, 760. ISBN 9780702053627. info
    not specified
  • http://portal.med.muni.cz/disciplina-13-farmakologie
  • http://portal.med.muni.cz/clanek-461-farmakovigilance-a-propagace-leciv.html
  • https://is.muni.cz/auth/el/1411/podzim2008/VLFA0722p/um/Zasady_antibioticke_ lecby.pdf?fakulta=1411;obdobi=4343;kod=VLFA0722p
  • http://portal.med.muni.cz/clanek-367-vyzkum-novych-leciv-od-zrodu-k-registraci.html
  • Practicals in Pharmacology http://portal.med.muni.cz/discipline-13-pharmacology
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
  • Lippincott's Illustrated Reviews : Pharmacology, 4th Ed., Harvey, Richard A. - Champe, Pamela C. - Finkel, Richard - Cubeddu, Luigi - Clarke, Michelle A. 2008. 560 s. ISBN-10: 0-7817-7155-2, ISBN-13: 978-0-7817-7155-9
  • Pharmaceutical Practice. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone. , 3rd Ed. 2004. ISBN 0443 07206 X
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
  • http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 2., zcela přeprac. a doplň. Praha: Grada, 2014. ISBN 9788024713564. info
  • RANG, H. P. Rang and Dale's pharmacology. 6th ed. [S.l.]: Churchill Livingstone, 2007. xiii, 829. ISBN 9780443069116. info
  • DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006. 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
Teaching methods
Drug classes specifics from the Syllabus are read firstly by the teacher and presented in video-programmes if available followed by discussion and training of drug prescription with the use of drug compendia and the computer database of the preparations registered in the Czech Republic (AISLP). Each student is asked to get ready as a homework to report on a specific pharmacological topic.
Assessment methods
The participation in practicals is obligatory and registered. To get credits a student has to pass 4 written tests: a) 2 on special drug presriptions (assessed individually by the teacher), b) 2 multiple-choice tests on knowledge of topics taught (more than half correctly answered questions required).
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019.
  • Enrolment Statistics (Autumn 2015, recent)
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